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US3789119A Expired / Lapsed US ⏱️ 0.0 years remaining

Stabilized molded sublingual nitroglycerin tablets

Assignee: Parke Davis and Co LLC
•
Filing: 1971-06-01
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Granted: 1974-01-29
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Expires: 1991-06-01
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Abstract

Abstract Pharmaceutical compositions containing minor proportions of nitroglycerin and a non-volatile, water-soluble solvent in combination with a major proportion of a solid, water-soluble pharmaceutical carrier. Those compositions, in the form of tablets suitable for sublingual administration, can be produced by wetting a substantially dry mixture of the nitroglycerin and the solid, water-soluble pharmaceutical carrier with a solvent mixture containing a non-volatile, water-soluble solvent and a volatile solvent, forming the wetted mixture into tablets, and removing the volatile solvent.

Inventors

  • 👤 S Fusari
  • 👤 L Lueck

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 17:08
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/006; A61K31/00; A61K31/21; A61K9/20; A61K9/2004; A61K9/2013; A61K9/2018

Claims Analysis

Total Claims: 3
Claim 1
Independent Claim 25 words
A pharmaceutical composition according to claim 1 wherein the non-volatile, water-soluble solvent is a polyethylene glycol having an average molecular weight of 300 to 1,000.
Claim 2
Dependent Claim 21 words
A pharmaceutical composition according to claim 1 wherein the solid, water-soluble pharmaceutical carrier is substantially a mixture of lactose and sucrose.
Claim 3
Dependent Claim 21 words
A pharmaceutical composition according to claim 1 in the form of tablets containing 0.1 to 1.0 mg. of nitroglycerin per tablet.

References Cited (Backward Citations)

US1541744A Cited
US2540253A Cited
US2648698A Cited
US2698822A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1977-01-28 1977-07-30 1978-01-29 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1981-01-28 1981-07-30 1982-01-29 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1985-01-28 1985-07-30 1986-01-29 $7700.00 Window Closed / Lapsed

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