Chrysene derivatives

Claim 1

A pharmaceutical composition comprising a compound of formula (I) ArCH.sub.2 R.sup.1 (I) wherein Ar is a chrysene ring optionally substituted by one or two substituents, said substituents containing not more than four carbon atoms in total when taken together, being the same or different and are selected from halogen; cyano; C 1-4 alkyl or C 1-4 alkoxy, each optionally substituted by hydroxy or C 1-2 alkoxy; halogen substituted C 1-2 alkyl or C 1-2 alkoxy; a group S(O) n R 2 wherein n is an integer 0, 1 or 2 and r 2 is C 1-2 alkyl optionally substituted by hydroxy or C 1-2 alkoxy; or the chrysene ring is optionally substituted by a group NR 3 R 4 containing not more than 5 carbon atoms wherein R 3 and R 4 are the same or different and each is a C 1-3 alkyl group; R 1 contains not more than eight carbon atoms and is a group ##STR11## wherein m is 0 or 1; R 5 is hydrogen; R 6 and R 7 are the same or different and each is hydrogen or C 1-3 alkyl optionally substituted by hydroxy; R 8 and R 9 are the same or different and each is hydrogen or C 1-3 alkyl; ##STR12## is a five-or six-membered saturated carbocyclic ring; R 10 is hydrogen, methyl or hydroxymethyl; R 11 , R 12 and R 13 are the same or different and each is hydrogen or methyl; R 14 is hydrogen, methyl, hydroxy, hydroxymethyl, a C 1-6 alkylcarboxylic acid ester, or ether or a pharmaceutically acceptable salt thereof, together with a pharmaceutically acceptable carrier therefor, except that the composition does not include the compound 2-((6-chrysenylmethyl)amino-2-methyl-1,3-propanediol or a pharmaceutically acceptable salt thereof.