US4530800A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Perylene derivatives
Assignee: SmithKline Beecham Corp
•
Filing: 1983-06-01
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Granted: 1985-07-23
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Expires: 2003-06-01
Abstract
Abstract The present invention relates to compounds of formula (I) <IMAGE> (I) wherein Ar is a perylene or substituted perylene ring system; R1 is a C1-3 alkylene moiety; R2 is hydrogen or a C1-6 alkyl group; R3 is hydroxyl C1-6 alkyl group; R4 and R5 are the same or different and are hydrogen, C1-6 alkyl or hydroxy C1-6 alkyl, esters thereof derived from condensation of carboxylic acids and hydroxyl groups of R3, R4, and R5; Acid addition salts thereof, which have been found useful for the treatment of tumors in mammals.
Inventors
- 👤 Kenneth W. Bair
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 03:12
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/045; C; C07; C07C; C07C215/00; C07C215/02; C07C215/04; C07C215/20; A61P; A61P31/00; A61P35/00; C07C205/00; C07C205/13; C07C205/14; C07C205/15; C07C215/06; C07C215/10; C07C215/22; C07C215/28; C07C215/42; C07C217/00; C07C217/02; C07C217/48; C07C217/54; C07C217/56; C07C217/58; C07C255/00; C07C255/49; C07C255/58; C07C317/00; C07C317/26; C07C317/32; C07C323/00; C07C323/23; C07C323/31; C07C323/32; C07D; C07D231/00; C07D231/02; C07D231/10; C07D231/12; C07D233/00; C07D233/54; C07D233/56; C07D249/00; C07D249/02; C07D249/08; C07D263/00; C07D263/52; C07D263/62; C07D263/64; C07D295/00; C07D295/04; C07D295/12; C07D295/135; C07D309/00; C07D309/02; C07D309/08; C07D309/10; C07D309/12; C07D319/00; C07D319/04; C07D319/06; C07J; C07J63/00; C07J63/008; C07C2601/00; C07C2601/12; C07C2601/14; C07C2603/00; C07C2603/02; C07C2603/04; C07C2603/22; C07C2603/24; C07C2603/26; C07C2603/40; C07C2603/42; C07C2603/48; C07C2603/50
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
1 words
2-methyl-2-((3-perylenylmethyl)amino)-1,3-propanediol.
Claim 2
Dependent Claim
1 words
2-methyl-2-((3-perylenylmethyl)amino)-1,3-propanediol.
Claim 3
Dependent Claim
20 words
A compound 2-methyl-2-((3-perylenylmethyl)amino)-1,3-propanediol or a C 1-6 alkylcarboxylic acid ester derived therefrom or a pharmaceutically acceptable acid addition salt thereof.
Claim 4
Dependent Claim
20 words
A compound 2-methyl-2-((3-perylenylmethyl)amino)-1,3-propanediol or a C 1-6 alkylcarboxylic acid ester derived therefrom or a pharmaceutically acceptable acid addition salt thereof.
Claim 5
Dependent Claim
10 words
The hydrochloric acid salt of the compound of claim 2.
Claim 6
Dependent Claim
10 words
The hydrochloric acid salt of a comound of claim 2.
Claim 7
Dependent Claim
10 words
The citric acid salt of a compound of claim 2.
Claim 8
Dependent Claim
10 words
The acetic acid salt of a compound of claim 2.
Claim 9
Dependent Claim
10 words
The methanesulfonic acid salt of a compound of claim 2.
Claim 10
Dependent Claim
6 words
A pharmaceutically acceptable salt of 2-methyl-2-((3-perylenylmethyl)amino-1,3-propanediol.
Claim 11
Dependent Claim
6 words
A pharmaceutically acceptable salt of 2-methyl-2-((3-perylenylmethyl)amino-1,3-propanediol.
References Cited (Backward Citations)
US4258181A
Cited
US4997249A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1988-07-22 | 1989-01-21 | 1989-07-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-07-22 | 1993-01-21 | 1993-07-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-07-22 | 1997-01-21 | 1997-07-23 | $7700.00 | Window Closed / Lapsed |