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US4719048A Expired / Lapsed US ⏱️ 0.0 years remaining

Crysene compound

Assignee: SmithKline Beecham Corp
•
Filing: 1984-10-18
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Granted: 1988-01-12
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Expires: 2004-10-18
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Abstract

Abstract The present invention relates to compounds of formula (I) ArCH2R1 (I) or a monomethyl or a monoethyl ether thereof (the compound of formula (I) including these ethers may contain no more than 30 carbon atoms in total); ethers, esters thereof; acid addition salts thereof; wherein Ar is a chrysene or substituted chrysene ring system; R1 contains not more than eight carbon atoms and is a group <IMAGE> wherein m is 0 or 1; R5 is hydrogen; R6 and R7 are the same or different and each is hydrogen or C1-3 alkyl optionally substituted by hydroxy; R8 and R9 are the ame or different and each is hydrogen or C1-3 alkyl; <IMAGE> is a five- or six-membered saturated carbocyclic ring; R10 is hydrogen, methyl or hydroxymethyl; R11, R12 and R13 are the same or different and each is hydrogen or methyl; R14 is hydrogen, methyl, hydroxy, or hydroxymethyl.

Inventors

  • 👤 Kenneth W. Bair

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 21:02
CPC Classifications
C; C07; C07J; C07J63/00; C07J63/008; C07C; C07C2603/00; C07C2603/02; C07C2603/40; C07C2603/42; C07C2603/48

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 18 words
2-((6-chrysenylmethyl)amino)2-methyl-1,3-propanediol or a C 1-6 alkylcarboxylic acid ester derived therefrom or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim 18 words
2-((6-chrysenylmethyl)amino)2-methyl-1,3-propanediol or a C 1-6 alkylcarboxylic acid ester derived therefrom or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim 10 words
The citric acid salt of a compound of claim 1.
Claim 4
Dependent Claim 10 words
The lactic acid salt of a compound of claim 1.
Claim 5
Dependent Claim 10 words
The 2-hydroxyethanesulfonic acid salt of a compound of claim 1.
Claim 6
Dependent Claim 10 words
The hydrochloric acid salt of a compound of claim 1.
Claim 7
Dependent Claim 2 words
2-((6-chrysenylmethyl)amino)-2-methyl-1,3-propanediol methanesulfonate.
Claim 8
Dependent Claim 2 words
2-((6-chrysenylmethyl)amino)-2-methyl-1,3-propanediol methanesulfonate.
Claim 9
Dependent Claim 1 words
2-((6-chrysenylmethyl)amino)-2-methyl-1,3-propanediol.
Claim 10
Dependent Claim 1 words
2-((6-chrysenylmethyl)amino)-2-methyl-1,3-propanediol.
Claim 11
Dependent Claim 8 words
A pharmaceutically acceptable acid addition salt of 2-((6-chreysenylmethyl)amino)-2-methyl-1,3-propanediol.
Claim 12
Dependent Claim 8 words
A pharmaceutically acceptable acid addition salt of 2-((6-chreysenylmethyl)amino)-2-methyl-1,3-propanediol.

References Cited (Backward Citations)

US2734920A Cited
US2865925A Cited
US3052722A Cited
US4034040A Cited
EP0125702A2 Cited
US4530800A Cited
US4532344A Cited
US4551282A Cited
US4511582A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-01-11 1991-07-13 1992-01-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-01-11 1995-07-13 1996-01-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-01-11 1999-07-13 2000-01-12 $7700.00 Window Closed / Lapsed

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