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Method and compounds for reducing dermal inflammations

Assignee: Individual
•
Filing: 1987-07-20
•
Granted: 1989-05-02
•
Expires: 2007-07-20
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Abstract

Abstract Dermal inflammations which are induced and propagated by leukotrienes are treated by topically applying to the inflamed dermis the following compound: ##STR1## wherein R 3 is H or a thiol; n is 1 to 12; p is 0 to 12; X is a substituted carbonyl, such as an ester or a carboxylic acid; and Y is an aliphatic or branched hydrocarbon, aromatic ring, carbonyl or substituted amide.

Inventors

  • 👤 Lee R. Morgan

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 14:58
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/185; A61K31/19; A61K31/195

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 40 words
A compound for treating dermal inflammations, comprising: ##STR24## wherein R 3 is H or thiol; n is 1-12; p is 0-12; X is a substituted carbonyl; wherein ##STR25## and wherein R 4 or R 5 is an electron donating group.
Claim 2
Dependent Claim 40 words
A compound for treating dermal inflammations, comprising: ##STR24## wherein R 3 is H or thiol; n is 1-12; p is 0-12; X is a substituted carbonyl; wherein ##STR25## and wherein R 4 or R 5 is an electron donating group.
Claim 3
Dependent Claim 14 words
The compound of claim 1 wherein R 4 is a substituted or unsubstituted amine.
Claim 4
Dependent Claim 11 words
The compound of claim 1 wherein R 5 is an alkenyl.
Claim 5
Dependent Claim 10 words
The compound of claim 1 wherein R 1 is ##STR26##
Claim 6
Dependent Claim 10 words
The compound of claim 1 wherein R 3 is ##STR27##
Claim 7
Dependent Claim 20 words
The compound of claim 1 wherein R 3 is H, n is 2, p is 0 and X is --COOH.
Claim 8
Dependent Claim 20 words
The compound of claim 1 wherein R 3 is H, n is 1, p is 0 and X is --COOH.
Claim 9
Dependent Claim 24 words
The compound of claim 1 wherein R 3 is H, n is 1, p is 0 and X is --COO--CH 2 --CH 3 .
Claim 10
Dependent Claim 10 words
The compound of claim 1 wherein the compound is ##STR28##
Claim 11
Dependent Claim 10 words
The compound of claim 1 wherein the compound is ##STR29##
Claim 12
Dependent Claim 10 words
The compound of claim 1 wherein the compound is ##STR30##
Claim 13
Dependent Claim 13 words
The compound of claim 1 wherein X is a carboxylic acid or ester.

References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-05-01 1992-10-31 1993-05-02 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-05-01 1996-10-31 1997-05-02 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-05-01 2000-10-31 2001-05-02 $7700.00 Window Closed / Lapsed

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