US4440788A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cysteine derivatives
Assignee: Mitsubishi Chemical Corp
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Filing: 1981-05-11
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Granted: 1984-04-03
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Expires: 2001-05-11
Abstract
Abstract This invention relates to S-alkylcysteines and processes for preparing same. The compounds according to this invention are expected to be applicable as therapeutic agents for hepatic failures.
Inventors
- 👤 Hiroshi Terayama
- 👤 Yoshiharu Morita
- 👤 Kohei Umezu
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 13:45
CPC Classifications
C; C07; C07D; C07D295/00; C07D295/16; C07D295/18; C07D295/182; C07D295/185; C07C; C07C323/00; C07C323/50; C07C323/51; C07C323/57; C07C323/58; C07C323/59
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
104 words
A method for accelerating regeneration of parenchymatous cells of the human or animal liver, when the number or function of said cells is reduced due to hepatic failure due to various hepatopathy inducing factors such as acute and chronic hepatitis or chemical poisoning, which comprises orally or parenterally administering to said human or animal a therapeutically effective amount of a cysteine derivative having the formula: ##STR43## wherein R 1 is methyl or ethyl, R 2 and R 3 are each hydrogen or a lower alkyl having about 1-6 carbon atoms, and R 4 is acetyl, or a non-toxic pharmaceutically acceptable acid addition salt thereof.
Claim 2
Independent Claim
104 words
A method for accelerating regeneration of parenchymatous cells of the human or animal liver, when the number or function of said cells is reduced due to hepatic failure due to various hepatopathy inducing factors such as acute and chronic hepatitis or chemical poisoning, which comprises orally or parenterally administering to said human or animal a therapeutically effective amount of a cysteine derivative having the formula: ##STR43## wherein R 1 is methyl or ethyl, R 2 and R 3 are each hydrogen or a lower alkyl having about 1-6 carbon atoms, and R 4 is acetyl, or a non-toxic pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
18 words
A method as claimed in claim 1, wherein said therapeutically effective amount is 0.1-500 mg/kg-body weight/day for animals.
Claim 4
Dependent Claim
18 words
A method as claimed in claim 1, wherein said therapeutically effective amount is 0.1-250 mg/kg-body weight/day for humans.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-04-03 | 1987-10-03 | 1988-04-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-04-03 | 1991-10-03 | 1992-04-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-04-03 | 1995-10-03 | 1996-04-03 | $7700.00 | Window Closed / Lapsed |