Patent US4797401A successfully refreshed from Google Patents.
US4797401A
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4-Substituted-1-(4-alkylsulphonamidophenyl)piperazines as antiarrhythmic agents
Assignee: Pfizer Inc
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Filing: 1987-07-15
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Granted: 1989-01-10
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Expires: 2007-07-15
Abstract
Abstract Antiarrhythmic agents of the formula:- <CHEM> and their pharmaceutically acceptable salts, wherein R and R<1>, which are the same or different, are C1-C4 alkyl, C3-C7 cycloalkyl, -CH2CF3, -CH2Cl, -CF3 or -NH2; R<2> and R<3>, which are the same or different , are H, halo, CF3, C1-C4 alkyl or C1-C4 alkoxy; and X is -CH2-, - @- or -CH(OH)-. m
Inventors
- 👤 John E. G. Kemp
- 👤 Peter E. Cross
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 19:32
CPC Classifications
C; C07; C07D; C07D295/00; C07D295/04; C07D295/12; C07D295/135; A; A61; A61P; A61P9/00; A61P9/06
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
90 words
A process for the prevention or reduction of cardiac arrhythmias in a human being which comprises administering to said human being a cardiac arrhythmia preventing or reducing amount of a compound of the formula (I): ##STR40## or a pharmaceutically acceptable salt thereof, wherein R and R 1 , which are the same or different, are C 1 -C 4 alkyl; R 2 and R 3 , which are the same or different, are H, halo or C 1 -C 4 alkyl; and X is --CH 2 --, ##STR41## or --CH(OH)--.
Claim 2
Dependent Claim
90 words
A process for the prevention or reduction of cardiac arrhythmias in a human being which comprises administering to said human being a cardiac arrhythmia preventing or reducing amount of a compound of the formula (I): ##STR40## or a pharmaceutically acceptable salt thereof, wherein R and R 1 , which are the same or different, are C 1 -C 4 alkyl; R 2 and R 3 , which are the same or different, are H, halo or C 1 -C 4 alkyl; and X is --CH 2 --, ##STR41## or --CH(OH)--.
Claim 3
Dependent Claim
31 words
A process according to claim 1 wherein R and R 1 are each CH 3 ; R 2 is H; and R 3 is H, CH 3 , Cl or F.
Claim 4
Dependent Claim
12 words
A process according to claim 2 wherein X is --CH 2 --.
Claim 5
Dependent Claim
37 words
The process according to claim 3 wherein R and R 1 are each CH 3 ; each of R 2 and R 3 is hydrogen; and X is --CH 2 --, said compound having the formula: ##STR42##
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-01-10 | 1992-07-11 | 1993-01-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-01-10 | 1996-07-11 | 1997-01-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-01-10 | 2000-07-11 | 2001-01-10 | $7700.00 | Window Closed / Lapsed |