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US4767615A
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Dental therapy by vesicle delivery
Assignee: DDS TECHNOLOGY Ltd
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Filing: 1986-06-24
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Granted: 1988-08-30
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Expires: 2006-06-24
Abstract
Abstract A known procedure is used to prepare liposomes of bipolar lipid membrane which are permeable and hence "leak" their contents at a rate which is variable by choice. The liposome is supplied with medication or cosmetic material for the oral cavity, or specifically for the teeth and gums. The liposome is then attached to a molecule that has affinity for the hydroxyapatite. Thus, the liposome will bind to oral cavity hydroxyapatite and bathe the surrounding support surface with its contents for extended hours of service.
Inventors
- 👤 W. Blair Geho
- 👤 Joseph Jacob
- 👤 John R. Lau
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 18:40
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K47/00; A61K47/50; A61K47/51; A61K47/54; A61K47/548; A61K47/69; A61K47/6905; A61K47/6911; A61K8/00; A61K8/02; A61K8/14; A61K9/00; A61K9/10; A61K9/127; A61K9/1271
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
98 words
A composition of matter for prolonged oral administration to a warm blooded animal of dental therapy and oral cavity breath freshener chemicals, comprising: a first component which is a tooth structure protective and therapeutic chemical or cosmetic breath freshener, said first component being encapsulated in or associated with; a second component which comprises lipid membrane structures in the form of vesicles; and a third component which is a molecule having a fatty substituent attached to the vesicle wall and a target substituent selected from the class consisting of chemicals which are classed biologically as having affinity for hydroxyapatite.
Claim 2
Dependent Claim
98 words
A composition of matter for prolonged oral administration to a warm blooded animal of dental therapy and oral cavity breath freshener chemicals, comprising: a first component which is a tooth structure protective and therapeutic chemical or cosmetic breath freshener, said first component being encapsulated in or associated with; a second component which comprises lipid membrane structures in the form of vesicles; and a third component which is a molecule having a fatty substituent attached to the vesicle wall and a target substituent selected from the class consisting of chemicals which are classed biologically as having affinity for hydroxyapatite.
Claim 3
Dependent Claim
36 words
The composition of matter as claimed in claim 1 wherein the third component target substituents are chemicals which are classed biologically as hydroxyapatite attracted being selected from the class consisting of diphosphonates, polyphosphoinositides and carboxylic acids.
References Cited (Backward Citations)
US4483929A
Cited
US4603044A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-08-30 | 1992-02-29 | 1992-08-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-08-30 | 1996-02-29 | 1996-08-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-08-30 | 2000-02-29 | 2000-08-30 | $7700.00 | Window Closed / Lapsed |