US4673567A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for preparing liposome composition
Assignee: Shionogi and Co Ltd
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Filing: 1985-08-08
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Granted: 1987-06-16
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Expires: 2005-08-08
Abstract
Abstract Novel process for liposome compositions capable to retain larger amount of drugs with a small amount of phospholipid and to provide, therefore, safer medications of various drugs, which comprises dispersing multilamella vesicles or small unilamella vesicles in an aqueous medium in the presence of one or more clinically active ingredients at or over a temperature of the gel/liquid crystal-phase transition wherein lyophilization may be made before or after the dispersion.
Inventors
- 👤 Hiroaki Jizomoto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 00:13
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/10; A61K9/127; A61K9/1277
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
40 words
A process for preparing liposome compositions which comprises dispersing lyophilized multilamella vesicles or small unilamella vesicles in an aqueous medium in the presence of one or more clinically active ingredients at or over a temperature of the gel-phase/liquid crystal-phase transition.
Claim 2
Dependent Claim
40 words
A process for preparing liposome compositions which comprises dispersing lyophilized multilamella vesicles or small unilamella vesicles in an aqueous medium in the presence of one or more clinically active ingredients at or over a temperature of the gel-phase/liquid crystal-phase transition.
Claim 3
Dependent Claim
26 words
A process claimed in claim 1, wherein said active ingredients are admixed with the vesicles before the lyophilization of said multilamella vesicles or small unilamella vesicles.
Claim 4
Dependent Claim
28 words
A process claimed in claim 1, wherein said active ingredients are admixed with said lyophilized multilamella vesicles or small unilamella vesicles and then dispersed in the aqueous medium.
Claim 5
Dependent Claim
18 words
A process claimed in claim 1, wherein the active ingredient is added in advance to the aqueous medium.
References Cited (Backward Citations)
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US4298594A
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US4483847A
Cited
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US4485054A
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US4532089A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-06-15 | 1990-12-15 | 1991-06-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-06-15 | 1994-12-15 | 1995-06-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-06-15 | 1998-12-15 | 1999-06-16 | $7700.00 | Window Closed / Lapsed |