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US4672056A
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Erythromycin A derivatives and method of use
Assignee: Abbott Laboratories
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Filing: 1985-11-12
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Granted: 1987-06-09
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Expires: 2005-11-12
Abstract
Abstract Erythromycin A derivatives with high antimicrobial activity are disclosed. 14-hydroxyerythromycin A and derivatives show superior in vitro antimicrobial activity compared to the parent compounds.
Inventors
- 👤 Prabhavathi Fernandes
- 👤 Leslie A. Freiberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 18:40
CPC Classifications
C; C07; C07H; C07H17/00; C07H17/04; C07H17/08; A; A61; A61P; A61P31/00; A61P31/04
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
37 words
A compound of the formula ##STR2## where R is selected from hydrogen, methyl and ethyl, and R' and R" are independently selected from hydroxyl or acyl of 2 to 20 carbon atoms, and pharmaceutically acceptable salts thereof.
Claim 2
Dependent Claim
37 words
A compound of the formula ##STR2## where R is selected from hydrogen, methyl and ethyl, and R' and R" are independently selected from hydroxyl or acyl of 2 to 20 carbon atoms, and pharmaceutically acceptable salts thereof.
Claim 3
Dependent Claim
10 words
A compound according to claim 1 wherein R is methyl.
Claim 4
Dependent Claim
31 words
A pharmaceutical composition in unit dosage form, comprising a compound according to claim 1 in an amount effective to treat or prevent a bacterial infection, in combination with a pharmaceutical carrier.
Claim 5
Dependent Claim
36 words
A method of treating and preventing bacterial infections in humans and lower animals in need of such treatment, comprising administering to the human or lower animal a therapeutically effective amount of the composition of claim 3.
References Cited (Backward Citations)
US4150220A
Cited
US4331803A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-06-08 | 1990-12-08 | 1991-06-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-06-08 | 1994-12-08 | 1995-06-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-06-08 | 1998-12-08 | 1999-06-09 | $7700.00 | Window Closed / Lapsed |