US4634587A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Sustained release quinidine dosage form
Assignee: Key Pharmaceuticals Inc
•
Filing: 1984-08-16
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Granted: 1987-01-06
•
Expires: 2004-08-16
Abstract
Abstract A sustained release quindine dosage form is made from a plurality of pellets. Each pellet includes a quinidine-containing coating over a nonpareil seed, with a further coating of about 5 to about 15% by weight of a mixture of about 1.5 to about 9 parts by weight ethylcellulose to about 1 part by weight hydroxypropylcellulose.
Inventors
- 👤 Charles H. Hsiao
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 00:58
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/50; A61K9/5073; A61K9/5078; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/47; A61K31/49
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
97 words
In a sustained release quinidine dosage form which comprises a compressed tablet or capsule, the improvement consisting essentially of plurality of pellets, the average pellet diameter greater than about 1 mm, each pellet consisting essentially of a coating of quinidine over a nonpareil seed, the thus quinidine-coated nonpareils are coated thereon with a coating consisting essentially of about 5% to about 15% by weight of a mixture of about 1.5 to about 9 parts by weight ethylcellulose to about 1 part by weight hydroxypropylcellulose, the sum of such pellets in forming a single dosage unit of quinidine.
Claim 2
Dependent Claim
97 words
In a sustained release quinidine dosage form which comprises a compressed tablet or capsule, the improvement consisting essentially of plurality of pellets, the average pellet diameter greater than about 1 mm, each pellet consisting essentially of a coating of quinidine over a nonpareil seed, the thus quinidine-coated nonpareils are coated thereon with a coating consisting essentially of about 5% to about 15% by weight of a mixture of about 1.5 to about 9 parts by weight ethylcellulose to about 1 part by weight hydroxypropylcellulose, the sum of such pellets in forming a single dosage unit of quinidine.
Claim 3
Dependent Claim
19 words
A sustained release quinidine dosage form of claim 1 wherein said quinidine is in the form of quinidine bisulfate.
Claim 4
Dependent Claim
24 words
A sustained release quinidine dosage form of claim 1 wherein the coating consisting essentially of 2.3 parts by weight ethylcellulose per part of hydroxypropylcellulose.
Claim 5
Dependent Claim
21 words
A sustained release quinidine dosage form of claim 1 wherein the weight of quinidine is approximately twice that of the nonpareil.
Claim 6
Dependent Claim
15 words
A sustained release quinidine dosage form of claim 1 wherein said container is a capsule.
Claim 7
Dependent Claim
20 words
A sustained release quinidine dosage form of claim 1 where in the plurality of pellets are compressed into a tablet.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-01-05 | 1990-07-07 | 1991-01-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-01-05 | 1994-07-07 | 1995-01-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-01-05 | 1998-07-07 | 1999-01-06 | $7700.00 | Window Closed / Lapsed |