US4628052A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical compositions containing dehydroepiandrosterone and other anesthetic steroids in the treatment of arthritis and other joint disabilities
Assignee: Individual
•
Filing: 1985-05-28
•
Granted: 1986-12-09
•
Expires: 2005-05-28
Abstract
Abstract The present invention is concerned with compositions and methods of treating rheumatoid arthritis, osteoarthritis, and arthritis associated with psoriasis and with lupus and other auto-immune diseases, and also for treating non-specific joint pain associated with stress or incidental to another ailment, using dehydroepiandrosterone and/or other anesthetic steroids dissolved in an oily vehicle, and preferably administered topically or orally.
Inventors
- 👤 Raymond F. Peat
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 13:25
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/56; A61K31/565; A61K31/57
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
26 words
A method for treating arthritis and joint pain and disability, comprising administering to a patient in need of such treatment a pharmacologically effective dose of dehydroepiandrosterone.
Claim 2
Independent Claim
26 words
A method for treating arthritis and joint pain and disability, comprising administering to a patient in need of such treatment a pharmacologically effective dose of dehydroepiandrosterone.
Claim 3
Independent Claim
70 words
A method for treating arthritis, comprising administering to a patient in need of such treatment a pharmacologically effective dose of at least one compound selected from the group of the anesthetic class of naturally occurring steroids of the formula: ##STR2## wherein R 1 is O or OH and R 2 is O, OH, or COCH 3 ; and which may contain one double bond in ring A and/or ring B.
Claim 4
Independent Claim
70 words
A method for treating arthritis, comprising administering to a patient in need of such treatment a pharmacologically effective dose of at least one compound selected from the group of the anesthetic class of naturally occurring steroids of the formula: ##STR2## wherein R 1 is O or OH and R 2 is O, OH, or COCH 3 ; and which may contain one double bond in ring A and/or ring B.
Claim 5
Dependent Claim
22 words
The method of claim 2 in which said steroid is selected from the group consisting of: dehydroepiandrosterone, iso-androsterone, etiocholanolone, pregnenolone, and progesterone.
Claim 6
Dependent Claim
11 words
The method of claim 2 wherein the compound is administered orally.
Claim 7
Dependent Claim
11 words
The method of claim 2 wherein the compound is administered topically.
Claim 8
Dependent Claim
13 words
The method of claim 2, wherein the arthritis to be treated is osteo-arthritis.
Claim 9
Dependent Claim
14 words
The method of claim 2, wherein the arthritis to be treated is rheumatoid arthritis.
Claim 10
Dependent Claim
17 words
The method of claim 2, wherein the arthritis to be treated is arthritis associated with auto-immune disease.
Claim 11
Dependent Claim
21 words
The method of claim 2, wherein the condition to be treated comprises non-specific joint pain or joint disability resulting from stress.
Claim 12
Dependent Claim
61 words
A pharmaceutical composition useful for the treatment of arthritis comprising an effective amount of at least one compound selected from the group consisting of the formula: ##STR3## wherein R 1 is O or OH and R 2 is O, or OH; and which may contain one double bond in ring A and/or ring B and tocopherol, in a suitable pharmaceutical carrier.
Claim 13
Dependent Claim
61 words
A pharmaceutical composition useful for the treatment of arthritis comprising an effective amount of at least one compound selected from the group consisting of the formula: ##STR3## wherein R 1 is O or OH and R 2 is O, or OH; and which may contain one double bond in ring A and/or ring B and tocopherol, in a suitable pharmaceutical carrier.
Claim 14
Dependent Claim
25 words
The composition of claim 10 in which said steroid is selected from the group consisting of dehydroepiandrosterone, iso-androsterone, and etiochlolanolone, in a suitable pharmaceutical carrier.
Claim 15
Dependent Claim
13 words
The composition of claim 11 comprising an effective amount of dehydroepiandrosterone and tocopherol.
Claim 16
Dependent Claim
8 words
The composition of claim 11 also comprising progesterone.
Claim 17
Dependent Claim
8 words
The composition of claim 11 also comprising testosterone.
Claim 18
Dependent Claim
9 words
The composition of claim 11 also comprising olive oil.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-12-08 | 1990-06-09 | 1990-12-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-12-08 | 1994-06-09 | 1994-12-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-12-08 | 1998-06-09 | 1998-12-09 | $7700.00 | Window Closed / Lapsed |