US4439432A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Treatment of progesterone deficiency and related conditions with a stable composition of progesterone and tocopherols
Assignee: Individual
•
Filing: 1982-03-22
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Granted: 1984-03-27
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Expires: 2002-03-22
Abstract
Abstract This invention relates to the composition of a biologically compatible high concentration solution of progesterone, which is stable and non-toxic, and which can be used transdermally, orally, and in suppository and pessary form for the correction of progesterone deficiency states and other diseases.
Inventors
- 👤 Raymond F. Peat
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 17:16
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/4841; A61K9/4858; A61K31/00; A61K31/56; A61K31/57; A61K47/00; A61K47/06; A61K47/22; A61K9/0012; A61K9/0014; A61K9/0034
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
9 words
A composition consisting essentially of progesterone solubilized in tocopherol.
Claim 2
Dependent Claim
9 words
A composition consisting essentially of progesterone solubilized in tocopherol.
Claim 3
Dependent Claim
23 words
A pharmaceutical composition suitable for administering progesterone to a patient in need thereof, comprising a pharmaceutically effective amount of progesterone solubilized in tocopherol.
Claim 4
Dependent Claim
23 words
A pharmaceutical composition suitable for administering progesterone to a patient in need thereof, comprising a pharmaceutically effective amount of progesterone solubilized in tocopherol.
Claim 5
Dependent Claim
21 words
The composition of claim 2 wherein progesterone is present at a concentration of from about 1% to about 25% by weight.
Claim 6
Dependent Claim
13 words
The composition of claim 2 also containing an emulsifier, water and a preservative.
Claim 7
Independent Claim
31 words
A method for administering progesterone to a patient in need thereof comprising administering to said patient by means other than intravenous injection, a pharmaceutically effective mixture of progesterone solubilized in tocopherol.
Claim 8
Independent Claim
31 words
A method for administering progesterone to a patient in need thereof comprising administering to said patient by means other than intravenous injection, a pharmaceutically effective mixture of progesterone solubilized in tocopherol.
Claim 9
Dependent Claim
13 words
The method of claim 5 which comprises the oral administration of said mixture.
Claim 10
Dependent Claim
13 words
The method of claim 5 which comprises the topical administration of said mixture.
Claim 11
Dependent Claim
19 words
The method of claim 5 which comprises placing said mixture in contact with the mucous membranes of the patient.
Claim 12
Independent Claim
57 words
The method of contraception in which a pharmaceutically effective amount of progesterone solubilized in tocopherol is applied to the vaginal membranes and the uterine cervix by means of a vaginal diaphragm, a pessary, or other means of vaginal application in which the composition is retained within the vagina for about four hours or more after each application.
Claim 13
Independent Claim
57 words
The method of contraception in which a pharmaceutically effective amount of progesterone solubilized in tocopherol is applied to the vaginal membranes and the uterine cervix by means of a vaginal diaphragm, a pessary, or other means of vaginal application in which the composition is retained within the vagina for about four hours or more after each application.
Claim 14
Independent Claim
24 words
A method for making a pharmaceutically effective composition for the administration of progesterone to a patient in need thereof comprising solubilizing progesterone in tocopherol.
Claim 15
Independent Claim
24 words
A method for making a pharmaceutically effective composition for the administration of progesterone to a patient in need thereof comprising solubilizing progesterone in tocopherol.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-03-27 | 1987-09-26 | 1988-03-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-03-27 | 1991-09-26 | 1992-03-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-03-27 | 1995-09-26 | 1996-03-27 | $7700.00 | Window Closed / Lapsed |