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US4576817A
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Enzymatic bandages and pads
Assignee: LACLEDE PROFESSIONAL PRODUCTS Inc A CORP OF NEW YORK
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Filing: 1984-06-07
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Granted: 1986-03-18
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Expires: 2004-06-07
Abstract
Abstract Enzymatic absorbent materials such as bandages and pads, for body contact applications, contain serum-activated oxidoreductase enzyme for producing hydrogen peroxide upon contact of the enzymatic materials with serum. An illustrative serum-activated oxidoreductase enzyme is glucose oxidase with the corresponding substrate in serum being glucose.
Inventors
- 👤 Robert E. Montgomery
- 👤 Michael A. Pellico
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:59
CPC Classifications
A; A61; A61L; A61L15/00; A61L15/16; A61L15/38; Y; Y10; Y10S; Y10S604/00; Y10S604/904
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
38 words
An enzymatic substantially organic absorbent material for body contact application containing, per gram of material, from about 1.0 to about 1,000 International Units of serum-activated oxidoreductase enzyme for producing hydrogen peroxide upon contact of said material with serum.
Claim 2
Dependent Claim
38 words
An enzymatic substantially organic absorbent material for body contact application containing, per gram of material, from about 1.0 to about 1,000 International Units of serum-activated oxidoreductase enzyme for producing hydrogen peroxide upon contact of said material with serum.
Claim 3
Dependent Claim
21 words
The enzymatic material of claim 1 wherein the concentration of oxidoreductase enzyme is from about 10 to about 500 International Units.
Claim 4
Dependent Claim
13 words
The enzymatic material of claim 1 wherein the oxidoreductase enzyme is glucose oxidase.
Claim 5
Dependent Claim
13 words
The enzymatic material of claim 1 wherein the oxidoreductase enzyme is oxalate oxidase.
Claim 6
Dependent Claim
24 words
The enzymatic material of claim 1 which also contains from about 0.1 to about 10,000 International Units of peroxidatic peroxidase per gram of material.
Claim 7
Dependent Claim
25 words
The enzymatic material of claim 5 wherein the concentration of peroxidatic peroxidase is from about 10 to about 500 International Units per gram of material.
Claim 8
Dependent Claim
12 words
The enzymatic material of claim 5 wherein the peroxidatic peroxidase is lactoperoxidase.
Claim 9
Dependent Claim
12 words
The enzymatic material of claim 5 wherein the peroxidatic peroxidase is myeloperoxidase.
Claim 10
Dependent Claim
40 words
The enzymatic material of claim 1 which also contains, per gram of material, from about 0.03 to about 1.2 millimoles of substrate specific to oxidoreductase enzyme in said material for producing hydrogen peroxide upon contact of said material with serum.
Claim 11
Dependent Claim
22 words
The enzymatic material of claim 9 wherein the concentration of substrate is from about 0.06 to 0.6 millimoles per gram of material.
Claim 12
Dependent Claim
18 words
The enzymatic material of claim 9 wherein the substrate is glucose and the oxidoreductase enzyme is glucose oxidase.
Claim 13
Dependent Claim
23 words
The enzymatic material of claim 11 which also contains from about 0.1 to about 10,000 International Units of lactoperoxidase per gram of material.
Claim 14
Dependent Claim
43 words
The enzymatic material of claim 5 which also contains, per gram of material, from about 0.0001to about 0.01 millimole of a metal salt of an oxygen accepting anion selected from the group consisting of thiocyanate, chloride and iodine or mixtures of such salts.
Claim 15
Dependent Claim
25 words
The enzymatic material of claim 13 wherein the concentration of the alkali metal salt is from about 0.001 to about 0.006 per gram of material.
Claim 16
Dependent Claim
14 words
The enzymatic material of claim 13 wherein the alkali metal salt is potassium thiocyanate.
Claim 17
Dependent Claim
37 words
The enzymatic material of claim 1 which also contains an aminoglucose selected from the group consisting of glucosamine, N-acetyl glucosamine and mixtures thereof in an amount from about 0.001 to about 0.002 millimole per gram of material.
Claim 18
Dependent Claim
25 words
The enzymatic material of claim 16 wherein the aminoglucose is present in an amount from about 0.0003 to about 0.001 millimole per gram of material.
Claim 19
Dependent Claim
19 words
The enzymatic material of claim 1 which also contains an effective amount of an enzymatic inhibitor specific to catalase.
Claim 20
Dependent Claim
28 words
The enzymatic material of claim 18 wherein the catalase inhibitor is an ascorbate salt in an amount from about 0.000001 to about 0.0001 millimole per gram of material.
Claim 21
Dependent Claim
41 words
An enzymatic substantially organic, absorbent fiber for conversion into enzymatic absorbent material for body contact application containing, per gram of fiber, from about 1.0 to about 1,000 International Units of serum-activated oxidoreductase enzyme for producing hydrogen peroxide upon contact with serum.
Claim 22
Dependent Claim
41 words
An enzymatic substantially organic, absorbent fiber for conversion into enzymatic absorbent material for body contact application containing, per gram of fiber, from about 1.0 to about 1,000 International Units of serum-activated oxidoreductase enzyme for producing hydrogen peroxide upon contact with serum.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-03-17 | 1989-09-16 | 1990-03-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-03-17 | 1993-09-16 | 1994-03-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-03-17 | 1997-09-16 | 1998-03-18 | $7700.00 | Window Closed / Lapsed |