US4560782A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Anti-tumor diplatinum coordination compounds
Assignee: RESEARCH Corp A NY NOT FOR PROFIT CORP
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Filing: 1983-11-02
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Granted: 1985-12-24
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Expires: 2003-11-02
Abstract
Abstract Diplatinum complexes of the formulas ##STR1## wherein X and Y are ligands, such as Cl and/or NH 3 , having antineoplastic activity.
Inventors
- 👤 Vassilios P. Papageorgiou
- 👤 Maria Bakola-Christianopoulou
- 👤 Constantinos A. Tsipis
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 10:16
CPC Classifications
C; C07; C07F; C07F15/00; C07F15/0006; C07F15/0086; C07F15/0093
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
56 words
A diplatinum complex having the general formula: ##STR4## wherein X and Y are monodentate ligands independently selected from the group consisting of NH 3 , Cl, lower alkyl amines, aryl amines, aralkyl amines, hydroxy lower alkylamines, hydroxylamine, lower alkoxyamines, alkoxyalkylamines, aminoacids, OH, Br, I, NO 2 , NO 3 , CN, SCN, monocarboxylates and the like.
Claim 2
Dependent Claim
56 words
A diplatinum complex having the general formula: ##STR4## wherein X and Y are monodentate ligands independently selected from the group consisting of NH 3 , Cl, lower alkyl amines, aryl amines, aralkyl amines, hydroxy lower alkylamines, hydroxylamine, lower alkoxyamines, alkoxyalkylamines, aminoacids, OH, Br, I, NO 2 , NO 3 , CN, SCN, monocarboxylates and the like.
Claim 3
Dependent Claim
18 words
The diplatinum complex of claim 1 wherein each X is Cl and each Y is NH 3 .
Claim 4
Dependent Claim
56 words
A diplatinum complex having the general formula: ##STR5## wherein X and Y are monodentate ligands independently selected from the group consisting of Cl, NH 3 , lower alkyl amines, aryl amines, aralkyl amines, hydroxy lower alkylamines, hydroxylamine, lower alkoxyamines, alkoxyalkylamines, aminoacids, OH, Br, I, NO 2 , NO 3 , CN, SCN, monocarboxylates and the like.
Claim 5
Dependent Claim
56 words
A diplatinum complex having the general formula: ##STR5## wherein X and Y are monodentate ligands independently selected from the group consisting of Cl, NH 3 , lower alkyl amines, aryl amines, aralkyl amines, hydroxy lower alkylamines, hydroxylamine, lower alkoxyamines, alkoxyalkylamines, aminoacids, OH, Br, I, NO 2 , NO 3 , CN, SCN, monocarboxylates and the like.
Claim 6
Dependent Claim
18 words
The diplatinum complex of claim 3 wherein each X is Cl and each Y is NH 3 .
Claim 7
Dependent Claim
24 words
A pharmaceutically acceptable composition in dosage unit form comprising the diplatinum complex of claims 1 or 2 in association with a pharmaceutically acceptable carrier.
Claim 8
Dependent Claim
17 words
The pharmaceutical composition of claim 5 wherein said diplatinum complex is provided in an anti-tumor effective amount.
Claim 9
Dependent Claim
24 words
A pharmaceutically acceptable composition in dosage unit form comprising the diplatinum complex of claim 3 or 4 in association with a pharmaceutically acceptable carrier.
Claim 10
Dependent Claim
7 words
A diplatinum complex having the formula: ##STR6##
Claim 11
Dependent Claim
7 words
A diplatinum complex having the formula: ##STR6##
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-12-23 | 1989-06-24 | 1989-12-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-12-23 | 1993-06-24 | 1993-12-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-12-23 | 1997-06-24 | 1997-12-24 | $7700.00 | Window Closed / Lapsed |