US3904663A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Compositions containing platinum
Assignee: Johnson Matthey PLC
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Filing: 1973-04-09
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Granted: 1975-09-09
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Expires: 1993-04-09
Abstract
Abstract The invention describes a composition which is active against ADJ/PC6 tumour in mice comprising a co-ordination complex of platinum (II) having the structure in which R1 to R4 are the same or different and are selected from the group consisting of hydrogen, alkyl, aryl, aralkyl, alkaryl, halogen, pseudohalogen, nitro, amido, amino, hydroxy, formyl, carboxylic acid, carboxylic acid salt, sulphonic acid, sulphonic acid salt and lkyl, aryl, aralkyl and alkaryl groups having as a substituent a member of the said group defined above and in which X and Y are halogenoid groups which may be the same or different.
Inventors
- 👤 Martin Leslie Tobe
- 👤 Abdul Rauf Khokhar
- 👤 Peter David Michael Braddock
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 05:30
CPC Classifications
C; C07; C07F; C07F15/00; C07F15/0006; C07F15/0086; C07F15/0093; A; A61; A61P; A61P35/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
36 words
A CO-ORDINATION COMPLEX OF PLATINUM (11) HAVING THE STRUCTURE: 1,2-DI(H2N-),3-R1,4-R2,5-R3,6-R4-BENZENE . X-PT-Y IN WHICH R1 AND R4 ARE HYDROGEN, R2 AND R3 ARE EITHER BOTH HYDROGEN OR BOTH LOWER ALKYL AND X AND Y ARE HALOGEN.
Claim 2
Dependent Claim
36 words
A CO-ORDINATION COMPLEX OF PLATINUM (11) HAVING THE STRUCTURE: 1,2-DI(H2N-),3-R1,4-R2,5-R3,6-R4-BENZENE . X-PT-Y IN WHICH R1 AND R4 ARE HYDROGEN, R2 AND R3 ARE EITHER BOTH HYDROGEN OR BOTH LOWER ALKYL AND X AND Y ARE HALOGEN.
Claim 3
Dependent Claim
17 words
A co-ordination complex according to claim 1 wherein R1-R4 are hydrogen and X and Y are chlorine.
Claim 4
Dependent Claim
21 words
A co-ordination complex according to claim 1 wherein R2 and R3 are methyl or ethyl and X and Y are chlorine.
Claim 5
Dependent Claim
12 words
A complex according to claim 3 wherein R2 and R3 are methyl.
Claim 6
Independent Claim
56 words
A method of preparation of dichloro (o-phenylenediamine) platinum (II) which comprises adding to o-phenylenediamine dihydrochloride to a filtered solution of an alkali metal chlorplatinate in hydrochloric acid solution in a covered vessel so that light is excluded and maintaining the resulting mixture at an elevated temperature, in the region of 50*C, for at least 12 hours.
Claim 7
Independent Claim
56 words
A method of preparation of dichloro (o-phenylenediamine) platinum (II) which comprises adding to o-phenylenediamine dihydrochloride to a filtered solution of an alkali metal chlorplatinate in hydrochloric acid solution in a covered vessel so that light is excluded and maintaining the resulting mixture at an elevated temperature, in the region of 50*C, for at least 12 hours.
Claim 8
Independent Claim
60 words
A method of preparation of dichloro (4,5 dimethyl o-phenylenediamine) platinum (II) which comprises adding 4,5 dimethyl o-phenylene diamine dihydrochloride to a filtered solution of an alkali metal chlorplatinate in hydrochloric acid solution in a covered vessel so that light is excluded and maintaining the resulting mixture at an elevated temperature in the region of 50*C, for at least 12 hours.
Claim 9
Independent Claim
60 words
A method of preparation of dichloro (4,5 dimethyl o-phenylenediamine) platinum (II) which comprises adding 4,5 dimethyl o-phenylene diamine dihydrochloride to a filtered solution of an alkali metal chlorplatinate in hydrochloric acid solution in a covered vessel so that light is excluded and maintaining the resulting mixture at an elevated temperature in the region of 50*C, for at least 12 hours.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-09-08 | 1979-03-10 | 1979-09-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-09-08 | 1983-03-10 | 1983-09-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-09-08 | 1987-03-10 | 1987-09-09 | $7700.00 | Window Closed / Lapsed |