Patent US4511352A successfully refreshed from Google Patents.
US4511352A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Parenteral delivery system with in-line container
Assignee: Alza Corp
•
Filing: 1984-05-14
•
Granted: 1985-04-16
•
Expires: 2004-05-14
Abstract
Abstract A parenteral delivery system is disclosed for delivering a beneficial agent to an agent recipient. The delivery system comprises a reservoir, a drip chamber and a flexible container that collapses as agent formulation leaves the system.
Inventors
- 👤 Felix Theeuwes
- 👤 John Urquhart
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 10:57
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/1407; A61M5/1409
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
182 words
A method for the administration of a beneficial drug to an animal, which method comprises: (a) admitting into the animal a delivery member in fluid communication with an intravenous delivery system, the system comprising: (1) a reservoir of a pharmaceutically acceptable fluid; (2) a drip chamber in fluid communication with the reservoir; (3) a container in fluid communication with the drip chamber and with the delivery member, the container comprising: (i) a wall that surrounds a lumen, said wall formed of a flexible material that moves from an expanded position to a collapsed position as drug formulation leaves the container; (ii) a passageway through the container, said passageway formed of a material that permits a fluid to enter the container and permits a fluid drug formulation to leave the container; (iii) a beneficial drug in the container that forms a fluid drug formulation with fluid that enters the container; and, (b) administering the drug to the animal by letting fluid enter the container to form the fluid drug formulation that, as the container collapses, leaves the container for administering to the animal.
Claim 2
Independent Claim
182 words
A method for the administration of a beneficial drug to an animal, which method comprises: (a) admitting into the animal a delivery member in fluid communication with an intravenous delivery system, the system comprising: (1) a reservoir of a pharmaceutically acceptable fluid; (2) a drip chamber in fluid communication with the reservoir; (3) a container in fluid communication with the drip chamber and with the delivery member, the container comprising: (i) a wall that surrounds a lumen, said wall formed of a flexible material that moves from an expanded position to a collapsed position as drug formulation leaves the container; (ii) a passageway through the container, said passageway formed of a material that permits a fluid to enter the container and permits a fluid drug formulation to leave the container; (iii) a beneficial drug in the container that forms a fluid drug formulation with fluid that enters the container; and, (b) administering the drug to the animal by letting fluid enter the container to form the fluid drug formulation that, as the container collapses, leaves the container for administering to the animal.
Claim 3
Dependent Claim
143 words
A parenteral delivery system for administering a beneficial drug to a recipient, the delivery system comprising; (a) a reservoir of a pharmaceutically acceptable fluid; (b) a drip chamber in fluid communication with the reservoir; and, (c) a container in fluid communication with the drip chamber, the container comprising: (1) a wall that surrounds a lumen, said wall formed of a flexible, fluid and agent impervious material capable of changing from a expanded to a collapsed position over time; (2) a passageway in the wall and extended through the lumen for letting fluid enter the lumen, and for letting a fluid drug formulation leave the lumen, the passageway formed of a material that permits the passage of fluid and fluid drug formulation over time; and, (3) a beneficial drug in the lumen that forms a fluid drug formulation with fluid that enters the container.
Claim 4
Dependent Claim
143 words
A parenteral delivery system for administering a beneficial drug to a recipient, the delivery system comprising; (a) a reservoir of a pharmaceutically acceptable fluid; (b) a drip chamber in fluid communication with the reservoir; and, (c) a container in fluid communication with the drip chamber, the container comprising: (1) a wall that surrounds a lumen, said wall formed of a flexible, fluid and agent impervious material capable of changing from a expanded to a collapsed position over time; (2) a passageway in the wall and extended through the lumen for letting fluid enter the lumen, and for letting a fluid drug formulation leave the lumen, the passageway formed of a material that permits the passage of fluid and fluid drug formulation over time; and, (3) a beneficial drug in the lumen that forms a fluid drug formulation with fluid that enters the container.
Claim 5
Dependent Claim
27 words
The parenteral delivery system for administering the beneficial drug according to claim 2, wherein the drug in the lumen is in a solid pharmaceutically acceptable dosage form.
Claim 6
Dependent Claim
34 words
The parenteral delivery system for administering the beneficial drug according to claim 2, wherein the drug in the lumen is in a delivery device that releases the drug to fluid that enters the lumen.
Claim 7
Dependent Claim
38 words
The parenteral delivery system for administering the beneficial drug according to claim 2, wherein an additional passageway extends through the lumen, said additional passageway formed of a material impervious to the passage of fluid and fluid drug formulation.
Claim 8
Dependent Claim
27 words
The parenteral delivery system for the administering the beneficial drug according to claim 2, wherein the delivery system comprises a fluid flow path that circumscribes the container.
Claim 9
Independent Claim
202 words
A method for administering a beneficial agent to an animal, which method comprises: (a) admitting into the animal a delivery member in fluid communication with an intravenous delivery system, the system comprising: (1) a reservoir of a pharmaceutically acceptable fluid; (2) a drip chamber in direct fluid communication with the reservoir and with the delivery member; and, (3) a fluid path that circumvents the direct path, said fluid path comprising: (i) a container in fluid communication with the reservoir and in fluid communication with the drip chamber, the container comprising: (a) a wall that surrounds an internal lumen, said wall formed of a flexible material that collapses as a drug formulation leaves the container; (b) a passageway through the lumen, said passageway form of a material that permits a fluid to enter the lumen and permits a fluid drug formulation to leave the lumen; (c) a beneficial drug in the lumen that forms a fluid drug formulation with fluid that enters the lumen; and, (b) administering the drug to the animal by letting fluid enter the container to form the fluid drug formulation, that as the container collapses, leaves the container and passes through the drip chamber for administering to the animal.
Claim 10
Independent Claim
202 words
A method for administering a beneficial agent to an animal, which method comprises: (a) admitting into the animal a delivery member in fluid communication with an intravenous delivery system, the system comprising: (1) a reservoir of a pharmaceutically acceptable fluid; (2) a drip chamber in direct fluid communication with the reservoir and with the delivery member; and, (3) a fluid path that circumvents the direct path, said fluid path comprising: (i) a container in fluid communication with the reservoir and in fluid communication with the drip chamber, the container comprising: (a) a wall that surrounds an internal lumen, said wall formed of a flexible material that collapses as a drug formulation leaves the container; (b) a passageway through the lumen, said passageway form of a material that permits a fluid to enter the lumen and permits a fluid drug formulation to leave the lumen; (c) a beneficial drug in the lumen that forms a fluid drug formulation with fluid that enters the lumen; and, (b) administering the drug to the animal by letting fluid enter the container to form the fluid drug formulation, that as the container collapses, leaves the container and passes through the drip chamber for administering to the animal.
Claim 11
Dependent Claim
160 words
A parenteral delivery system for administering a beneficial drug to a recipient, the delivery system comprising: (a) a reservoir of a pharmaceutically acceptable fluid; (b) a drip chamber in direct fluid communication with the reservoir; and, (c) a fluid path that circumvents the direct path, said circumventing fluid path comprising: (i) a container in fluid communication with the reservoir and in fluid communication with the drip chamber; said container comprising: (a) a wall that surrounds an internal lumen, said wall formed of a flexible material that collapses as a drug formulation leaves the container; (b) a passageway through the lumen for letting fluid enter the lumen and for letting fluid drug formulation leave the lumen, said passageway formed of a material that permits the passage of fluid into the lumen and permits the passage of drug formulation from the lumen; and, (c) a beneficial drug in the lumen that forms a fluid drug formulation with fluid that enter the lumen.
Claim 12
Dependent Claim
160 words
A parenteral delivery system for administering a beneficial drug to a recipient, the delivery system comprising: (a) a reservoir of a pharmaceutically acceptable fluid; (b) a drip chamber in direct fluid communication with the reservoir; and, (c) a fluid path that circumvents the direct path, said circumventing fluid path comprising: (i) a container in fluid communication with the reservoir and in fluid communication with the drip chamber; said container comprising: (a) a wall that surrounds an internal lumen, said wall formed of a flexible material that collapses as a drug formulation leaves the container; (b) a passageway through the lumen for letting fluid enter the lumen and for letting fluid drug formulation leave the lumen, said passageway formed of a material that permits the passage of fluid into the lumen and permits the passage of drug formulation from the lumen; and, (c) a beneficial drug in the lumen that forms a fluid drug formulation with fluid that enter the lumen.
Claim 13
Dependent Claim
26 words
The parenteral delivery system for administering the beneficial drug according to claim 8, wherein the drug in the lumen is in a solid pharmaceutically acceptable form.
Claim 14
Dependent Claim
34 words
The parenteral delivery system for administering the beneficial drug according to claim 8, wherein the drug in the lumen is in a delivery device that releases the drug to fluid that enters the lumen.
Claim 15
Dependent Claim
42 words
The parenteral delivery system for administering the beneficial drug according to claim 8, wherein an additional passageway extends through the lumen, said additional passageway formed of a material impermeable to the passage of fluid and impermeable to the passage of drug formulation.
Claim 16
Dependent Claim
22 words
The parenteral delivery system for administering the beneficial drug according to claim 8, wherein the delivery system comprises a flow regulator clamp.
References Cited (Backward Citations)
US2954028A
Cited
US3001525A
Cited
GB982107A
Cited
US3305446A
Cited
CH497181A
Cited
US3322114A
Cited
US4061141A
Cited
US3993073A
Cited
US3854480A
Cited
US3797494A
Cited
US3995631A
Cited
US3797485A
Cited
US3756237A
Cited
US3760984A
Cited
US3948254A
Cited
US3756390A
Cited
US3845770A
Cited
US3921636A
Cited
US4177256A
Cited
US3848603A
Cited
US3921635A
Cited
US3941126A
Cited
US3993072A
Cited
US3976068A
Cited
US4203439A
Cited
US4323457A
Cited
US4217894A
Cited
US4233973A
Cited
US4256104A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-04-15 | 1988-10-15 | 1989-04-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-04-15 | 1992-10-15 | 1993-04-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-04-15 | 1996-10-15 | 1997-04-16 | $7700.00 | Window Closed / Lapsed |