US4217894A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Apparatus for supplying medication to the human or animal body
Assignee: Siemens AG
•
Filing: 1978-05-04
•
Granted: 1980-08-19
•
Expires: 1998-05-04
Abstract
Abstract In the illustrated embodiments, medication is stored in an implantable housing in solid form, and solvent is supplied to the solid medication to form the infusion fluid as needed for maintaining the desired dosage rate. The rate of supply of solvent may be controlled to insure a saturated solution of the medication under all operating conditions. The solvent may be the local bodily fluid which enters the housing via a semipermeable membrane, or a sealed solvent reservoir may be provided within the housing.
Inventors
- 👤 Manfred Franetzki
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:53
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/142; A61M5/14244; A61M5/14276; A61M5/1407; A61M5/1409; A61M2202/00; A61M2202/06; A61M2205/00; A61M2205/35; A61M2205/3507; A61M2205/3523
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
239 words
Apparatus for the infusion of medical fluids into the human or animal body, comprising in combination: a storage receptacle having reservoir means providing a reservoir (5, 18) with a fluid inlet (8, 23) providing a fluid passage leading to said reservoir (5, 18) and with a discharge port (12, 27) providing a fluid passage leading from said reservoir (5, 15), a solid medication (9, 24) disposed in said reservoir (5, 18) such that the fluid inlet (8, 23) provides a fluid passage in fluid communication with said solid medication, a conveyance and dosing unit in fluid communication with said fluid inlet (8, 23) comprising supplying means for the supply of a solvent to said solid medication (9, 24) via the fluid passage provided by said fluid inlet such that the solvent progressively dissolves the solid medication to form a medical fluid in the vicinity of said solid medication in said reservoir, said storage receptacle being constructed to accommodate supply of said medical fluid so formed in said reservoir (5, 15), to said discharge port (12, 27), while retaining in said reservoir undissolved portions of said solid medication, and said conveyance and dosing unit being operable to control the dose of said medical fluid supplied to said discharge port by controlling the transport of solvent to said reservoir whereby in the storage receptacle the amount of solid medication dissolved per dose of medical fluid corresponds to a desired dosing schedule.
Claim 2
Dependent Claim
239 words
Apparatus for the infusion of medical fluids into the human or animal body, comprising in combination: a storage receptacle having reservoir means providing a reservoir (5, 18) with a fluid inlet (8, 23) providing a fluid passage leading to said reservoir (5, 18) and with a discharge port (12, 27) providing a fluid passage leading from said reservoir (5, 15), a solid medication (9, 24) disposed in said reservoir (5, 18) such that the fluid inlet (8, 23) provides a fluid passage in fluid communication with said solid medication, a conveyance and dosing unit in fluid communication with said fluid inlet (8, 23) comprising supplying means for the supply of a solvent to said solid medication (9, 24) via the fluid passage provided by said fluid inlet such that the solvent progressively dissolves the solid medication to form a medical fluid in the vicinity of said solid medication in said reservoir, said storage receptacle being constructed to accommodate supply of said medical fluid so formed in said reservoir (5, 15), to said discharge port (12, 27), while retaining in said reservoir undissolved portions of said solid medication, and said conveyance and dosing unit being operable to control the dose of said medical fluid supplied to said discharge port by controlling the transport of solvent to said reservoir whereby in the storage receptacle the amount of solid medication dissolved per dose of medical fluid corresponds to a desired dosing schedule.
Claim 3
Dependent Claim
68 words
Apparatus according to claim 1, characterized in said supplying means for the solvent comprising a semipermeable membrane (7) having its exterior side in communication with the body fluid of the body receiving the medication and having its interior side communicating with said reservoir means (5, 18) for the supply of the body fluid to the reservoir means as solvent for dissolving the solid medication in said reservoir means.
Claim 4
Dependent Claim
30 words
Apparatus according to claim 2, characterized in said semipermeable membrane (7) being permeable only to low-molecular substances of molecular size not substantially exceeding the molecular size of the water molecule.
Claim 5
Dependent Claim
32 words
Apparatus according to claim 1, characterized in the supplying means for supplying the solvent comprising an absorptive wick disposed in fluid communication with the body fluid of the body receiving the medication.
Claim 6
Dependent Claim
34 words
Apparatus according to claim 2 or 3, characterized in the supplying means for supplying the solvent comprising material with hydrophilic properties in fluid communication with the body fluid of the body receiving the medication.
Claim 7
Dependent Claim
42 words
Apparatus according to claim 1 with the solvent supplying means for supplying the solvent comprising an additional reservoir (19) for storing the solvent and for supplying the solvent to said reservoir means (18) for the purpose of dissolving the solid medication (24).
Claim 8
Dependent Claim
51 words
Apparatus according to claim 1, characterized in that the reservoir means contains an amount of said solid medication (9, 24) coordinated with the flow of the solvent thereto such that a fully saturated solution results for all rates of transport of the medication by the conveyance and dosing unit (2, 15).
Claim 9
Dependent Claim
49 words
Apparatus according to claim 1, characterized in the reservoir means (5,18) containing a block of the solid medication (9, 24) and being constructed to provide at least one through-flow channel for the solvent so that the solvent flows through the block of solid medication during operation of the apparatus.
Claim 10
Dependent Claim
30 words
Apparatus according to claim 8, characterized in the block of said solid medication (9, 24) with its entire volume in the reservoir means (5, 18) being porous to the solvent.
Claim 11
Dependent Claim
40 words
Apparatus according to claim 8, characterized in fine-meshed filter means (10, 11; 25, 26) confining the solid medication for the purpose of preventing the flow of undissolved particles of the solid medication (9, 24) to the discharge port (12, 27).
Claim 12
Dependent Claim
64 words
Apparatus according to claim 1, characterized in that the conveyance and dosing unit (2, 15) comprises pump means having its inlet side connected with the solvent supplying means (7, 19) and having its output side connected with said reservoir means (5, 18), said pump means being operated at a rate such that a fully saturated solution is supplied to said discharge port (12, 27).
Claim 13
Dependent Claim
14 words
Apparatus according to claim 11, characterized in said pump means comprising a stricture pump.
Claim 14
Dependent Claim
17 words
Apparatus according to claim 11 characterized in said pump means for the solvent comprising an electro-osmotic pump.
Claim 15
Dependent Claim
35 words
Apparatus according to claim 1, characterized in an apparatus housing (1, 14) containing said reservoir means and said conveyance and dosing unit and having a cathether (13, 28) arranged at said discharge port (12, 27).
Claim 16
Dependent Claim
42 words
Apparatus according to claim 11, characterized in a temperature sensor means controlling said pump means (2, 15) for correcting the conveying capacity of the pump means in accordance with the temperature-dependent solubility curve of the solvent for the solid medication (9, 24).
Claim 17
Dependent Claim
58 words
A medication supply system according to claim 1 with said reservoir means (5, 18) having said solid medication (9, 24) therein, and confining means (10, 11; 25, 26) for confining solid particles from the solid medication against flow to said discharge port (12, 27) while accommodating flow of medication when dissolved in said solvent to said discharge port.
Claim 18
Dependent Claim
39 words
A medication supply system according to claim 16, with said medication supply means having means operable for supplying a substantially saturated solution of the medication to said discharge port (12, 27) under all operating conditions of said infusion apparatus.
Claim 19
Dependent Claim
48 words
A medication supply system according to claim 16, with said solvent supply means comprising means (7) for communication with ambient body fluid of the body receiving the medication and for supplying such ambient body fluid to said reservoir means (5) as the solvent for dissolving the solid medication.
Claim 20
Dependent Claim
32 words
A medication supply system according to claim 17 with said solvent supply means comprising means (19) for storing said solvent for supply to said reservoir means (18) for dissolving the solid medication.
Claim 21
Dependent Claim
21 words
A medication supply system according to claim 16 with an implantable housing containing said reservoir means and said solvent supply means.
References Cited (Backward Citations)
US3896806A
Cited
US3732865A
Cited
US3760805A
Cited
US3760804A
Cited
US3894538A
Cited
US3797492A
Cited
US3995632A
Cited
US4077405A
Cited
US4140122A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-08-19 | 1984-02-18 | 1984-08-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-08-19 | 1988-02-18 | 1988-08-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-08-19 | 1992-02-18 | 1992-08-19 | $7700.00 | Window Closed / Lapsed |