US4464474A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Non-A, non-B hepatitis assay and vaccine
Assignee: Sanofi Pasteur Ltd
•
Filing: 1980-07-09
•
Granted: 1984-08-07
•
Expires: 2000-07-09
Abstract
Abstract A newly discovered particle in the urine and serum of non-A, non-B hepatitis patients has been associated with non-A, non-B hepatitis. The particle resembles a togavirus and is 50-60 nm in diameter with a discrete core of about 40 nm in diameter. The virus loses its infectivity for tissue culture upon heating at 25° C. in aqueous suspension or by exposure to ether. The particle may be cultured in vitro or recovered from body fluids or tissues to make immunoassays and vaccines. The immunoassays may be employed to detect the particle antigens or antibodies thereto in test samples.
Inventors
- 👤 Pierre L. J. Coursaget
- 👤 Philippe C. Maupas
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 19:02
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/576; G01N33/5767; A; A61; A61K; A61K39/00; A61K39/12; A61K39/29; A61K2039/51; A61K2039/525; A61K2039/5252; A61K2039/555; A61K2039/55511; A61K2039/55566; C; C12; C12N; C12N2770/00; C12N2770/00011; C12N2770/24011; C12N2770/24211; C12N2770/24234; Y; Y10; Y10S; Y10S436/00; Y10S436/804; Y10S436/82
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
30 words
A method, which comprises assaying a sample suspected to contain NANB hepatatis virus antigens for an antigen of at least one of togavirus strains ATCC VR-2011, VR-2012, VR-2013 or VR-2014.
Claim 2
Independent Claim
30 words
A method, which comprises assaying a sample suspected to contain NANB hepatatis virus antigens for an antigen of at least one of togavirus strains ATCC VR-2011, VR-2012, VR-2013 or VR-2014.
Claim 3
Independent Claim
36 words
A method, which comprises assaying a sample suspected to contain immune globulin to NANB hepatitis for immune globulins capable of binding an antigen of at least one of togavirus strains ATCC VR-2011, VR-2012, Vr-2013 or VR-2014.
Claim 4
Independent Claim
36 words
A method, which comprises assaying a sample suspected to contain immune globulin to NANB hepatitis for immune globulins capable of binding an antigen of at least one of togavirus strains ATCC VR-2011, VR-2012, Vr-2013 or VR-2014.
Claim 5
Dependent Claim
11 words
The method of claim 2 wherein the immune globulin is IgM.
Claim 6
Dependent Claim
11 words
The method of claim 2 wherein the immune globulin is IgG.
Claim 7
Dependent Claim
38 words
An inmunoassay for determining NANB hepatitis infection in a patient, which comprises assaying a sample from said patient for IgM capable of binding an antigen of at least one of togavirus strains ATCC VR-2011, VR-2012, VR-2013 or VR-2014.
Claim 8
Dependent Claim
38 words
An inmunoassay for determining NANB hepatitis infection in a patient, which comprises assaying a sample from said patient for IgM capable of binding an antigen of at least one of togavirus strains ATCC VR-2011, VR-2012, VR-2013 or VR-2014.
Claim 9
Independent Claim
26 words
A method for recovering NANB hepatitis antigens, comprising separating from urine an antigen of at least one of togavirus strains ATCC VR-2011, VR-2012, VR-2013 or VR-2014.
Claim 10
Independent Claim
26 words
A method for recovering NANB hepatitis antigens, comprising separating from urine an antigen of at least one of togavirus strains ATCC VR-2011, VR-2012, VR-2013 or VR-2014.
Claim 11
Independent Claim
28 words
A method for detecting NANB hepatitis, which comprises assaying for a particle antigen of at least one of togavirus strains ATCC VR-2011, VR-2012, VR-2013 or VR-2014 in urine.
Claim 12
Independent Claim
28 words
A method for detecting NANB hepatitis, which comprises assaying for a particle antigen of at least one of togavirus strains ATCC VR-2011, VR-2012, VR-2013 or VR-2014 in urine.
Claim 13
Independent Claim
36 words
A method for assaying a sample suspected to contain NANB hepatitis virus antigens which comprises detecting or determining in said sample an antigen of at least one of togavirus strains ATCC VR-2011, VR-2012, VR-2013 or VR-2014.
Claim 14
Independent Claim
36 words
A method for assaying a sample suspected to contain NANB hepatitis virus antigens which comprises detecting or determining in said sample an antigen of at least one of togavirus strains ATCC VR-2011, VR-2012, VR-2013 or VR-2014.
References Cited (Backward Citations)
US3887697A
Cited
US4013411A
Cited
US4012494A
Cited
US4133873A
Cited
US4157280A
Cited
US4100267A
Cited
US4234564A
Cited
US4189464A
Cited
US4202665A
Cited
US4356164A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-08-07 | 1988-02-06 | 1988-08-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-08-07 | 1992-02-06 | 1992-08-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-08-07 | 1996-02-06 | 1996-08-07 | $7700.00 | Window Closed / Lapsed |