Patent US4884092A successfully refreshed from Google Patents.
Patent US4447449A successfully refreshed from Google Patents.
US4447449A
Expired / Lapsed
US
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Methods of treating ischemic states
Assignee: Pharmacia and Upjohn Co
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Filing: 1981-11-16
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Granted: 1984-05-08
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Expires: 2001-11-16
Abstract
Abstract The present invention relates to novel methods of use for known pharmacological anti-allergenic agents including disodiumchromoglycate (DSCG) and related compounds thereof, including generally bis chromones, benzopyrans, oxamic acids and salts or esters of each, preferably lodoxamide, its THAM salt and ethyl ester. All are subsequently included in the term biologues. The methods are for the treatment of pathological cardiovascular ischemic states in animals, particularly humans. Additionally, novel compositions including the biologues of the present invention in combination with known vasodilators and feed stuffs are also disclosed.
Inventors
- 👤 Norman B. Marshall
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 17:44
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/335; A61K31/35; A61K31/16; A61K31/165
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
58 words
A method of arresting or preventing a pathological cardiovascular ischemic state (PACVIS) in an animal exhibiting or particularly susceptible to development of said PACVIS which comprises: systemically administering to said animal an anti-PACVIS biologue in not less than a non-toxic amount effective to treat or prevent said PACVIS which comprises from 0.0001 mg to 400 mg per dose.
Claim 2
Independent Claim
58 words
A method of arresting or preventing a pathological cardiovascular ischemic state (PACVIS) in an animal exhibiting or particularly susceptible to development of said PACVIS which comprises: systemically administering to said animal an anti-PACVIS biologue in not less than a non-toxic amount effective to treat or prevent said PACVIS which comprises from 0.0001 mg to 400 mg per dose.
Claim 3
Dependent Claim
21 words
A method according to claim 1, wherein said PACVIS is myocardial ischemia or peripheral ischemia wherein said animal is a human.
Claim 4
Dependent Claim
21 words
A method according to claim 2 wherein said biologue is DSCG, lodoxamide, lodoxamide bis THAM salt, lodoxamide diethyl ester or proxicromil.
Claim 5
Dependent Claim
14 words
A method according to claim 3 wherein said biologue is lodoxamide bis THAM salt.
Claim 6
Dependent Claim
13 words
A method according to claim 3 wherein said biologue is lodoxamide diethyl ester.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-05-08 | 1987-11-07 | 1988-05-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-05-08 | 1991-11-07 | 1992-05-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-05-08 | 1995-11-07 | 1996-05-08 | $7700.00 | Window Closed / Lapsed |