US4055654A
Expired / Lapsed
US
⏱️ 0.0 years remaining
6,8-Di-t-butyl-4-oxo-4H-1-benzopyran-2-carboxylic acid and derivative for the prevention of asthmatic symptoms
Assignee: Fisons Ltd
•
Filing: 1976-01-02
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Granted: 1977-10-25
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Expires: 1996-01-02
Abstract
Abstract There are described certain mono-chromone-2-carboxylic acids of formula, ##STR1## having one substituent in the 5 or 6 position or having 2 or more substituents in the 5,6,7 or 8 positions. There are also described processes for making the compounds and pharmaceutical compositions, for the treatment of asthma, containing the compounds.
Inventors
- 👤 Hugh Cairns
- 👤 Albert Chambers
- 👤 Thomas Brian Lee
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 18:41
CPC Classifications
C; C07; C07C; C07C45/00; C07C45/61; C07C45/67; C07C45/45; C07C45/46; C07C45/68; C07C45/70; C07C45/71; C07D; C07D307/00; C07D307/02; C07D307/04; C07D307/10; C07D307/12
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
60 words
A composition useful for the prevention of asthmatic symptoms comprising an amount useful for the prevention of asthmatic symptoms of 6,8-di-t-butyl-4-oxo-4-H-1-benzopyran-2-carboxylic acid or a pharmaceutically acceptable salt, lower alkyl ester, ester with a di-lower alkylamine substituted lower alkanol, bis ester with a di-(hydroxy lower alkyl) ether or unsubstituted amide thereof, as active ingredient, in combination with a pharmaceutically acceptable carrier.
Claim 2
Dependent Claim
60 words
A composition useful for the prevention of asthmatic symptoms comprising an amount useful for the prevention of asthmatic symptoms of 6,8-di-t-butyl-4-oxo-4-H-1-benzopyran-2-carboxylic acid or a pharmaceutically acceptable salt, lower alkyl ester, ester with a di-lower alkylamine substituted lower alkanol, bis ester with a di-(hydroxy lower alkyl) ether or unsubstituted amide thereof, as active ingredient, in combination with a pharmaceutically acceptable carrier.
Claim 3
Dependent Claim
19 words
A composition according to claim 1 comprising from 0.17 to 600 mg. of active ingredient in unit dosage form.
Claim 4
Dependent Claim
13 words
A composition according to claim 1 comprising an effective amount of 6,8-di-t-butyl-4-oxo-4H-1-benzopyran-2-carboxylic acid.
Claim 5
Independent Claim
62 words
A method for inhibiting the symptoms of asthma in a patient having asthma which comprises administering to said patient, an effective amount of 6,8-di-t-butyl-4-oxo-4H-1-benzopyran-2-carboxylic acid or a pharmaceutically acceptable alt, lower alkyl ester with a di-lower alkylamine substituted lower alkanol, bis ester with a di-(hydroxy lower alkyl) ether or unsubstituted amide thereof, as active ingredient, in combination with a pharmaceutically acceptable carrier.
Claim 6
Independent Claim
62 words
A method for inhibiting the symptoms of asthma in a patient having asthma which comprises administering to said patient, an effective amount of 6,8-di-t-butyl-4-oxo-4H-1-benzopyran-2-carboxylic acid or a pharmaceutically acceptable alt, lower alkyl ester with a di-lower alkylamine substituted lower alkanol, bis ester with a di-(hydroxy lower alkyl) ether or unsubstituted amide thereof, as active ingredient, in combination with a pharmaceutically acceptable carrier.
References Cited (Backward Citations)
US3652765A
Cited
US3427324A
Cited
US3484445A
Cited
US3864493A
Cited
US3629290A
Cited
US3816470A
Cited
US3952013A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-10-24 | 1981-04-25 | 1981-10-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-10-24 | 1985-04-25 | 1985-10-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-10-24 | 1989-04-25 | 1989-10-25 | $7700.00 | Window Closed / Lapsed |