US4095028A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Substituted dioxamic acid esters
Assignee: Pharmacia and Upjohn Co
•
Filing: 1976-08-16
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Granted: 1978-06-13
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Expires: 1996-08-16
Abstract
Abstract Compounds represented below ##STR1## and pharmaceutical compositions thereof, the compositions including the non-substituted phenylene dioxamates are useful in the prophylactic treatment of sensitized mammals for allergy and all anaphylactic reactions of a reagin or non-reagin mediated nature.
Inventors
- 👤 Charles M. Hall
- 👤 John B. Wright
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 17:45
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/275; A61K31/277; A61K47/00; A61K47/06; A61K47/08; A61K47/14; A61K47/26; A61K47/44; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0043; A61K9/007; A61K9/0073; A61K9/08; A61K9/14; A61K9/16; A61K9/1605; A61K9/1611; A61K9/20; A61K9/2004; A61K9/2009; A61K9/2022; A61K9/205; A61K9/2054; A61K9/2059
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
52 words
A compound of the formula ##STR49## wherein R is alkyl of one to three carbon atoms, inclusive; Z is trifluoromethyl or ##STR50## wherein D is hydrogen or alkyl of one to three carbon atoms, inclusive; Y is hydrogen, methyl or chloro, with the proviso that when Z is trifluoromethyl, Y is chloro.
Claim 2
Dependent Claim
52 words
A compound of the formula ##STR49## wherein R is alkyl of one to three carbon atoms, inclusive; Z is trifluoromethyl or ##STR50## wherein D is hydrogen or alkyl of one to three carbon atoms, inclusive; Y is hydrogen, methyl or chloro, with the proviso that when Z is trifluoromethyl, Y is chloro.
Claim 3
Dependent Claim
15 words
A compound in accordance with claim 1 wherein Y is 2-chloro and Z is 5-trifluoromethyl.
Claim 4
Dependent Claim
15 words
A compound in accordance with claim 1 wherein Y is 2-methyl and Z is 5-carboxy.
Claim 5
Dependent Claim
15 words
A compound in accordance with claim 1 wherein Y is 2-chloro and Z is 5-carboxy.
Claim 6
Dependent Claim
15 words
A compound in accordance with claim 1 wherein Y is hydrogen and Z is 5-carboxy.
Claim 7
Dependent Claim
11 words
A compound in accordance with claim 2 wherein R is ethyl.
Claim 8
Dependent Claim
11 words
A compound in accordance with claim 3 wherein R is ethyl.
Claim 9
Dependent Claim
21 words
A compound in accordance with claim 1 wherein R is ethyl, Y is chloro, Z is ##STR51## and D is methyl.
Claim 10
Dependent Claim
21 words
A compound in accordance with claim 1 wherein R is ethyl, Y is hydrogen, Z is ##STR52## and D is methyl.
Claim 11
Dependent Claim
53 words
Compounds of the formula ##STR53## wherein R is selected from the group consisting of, alkyl of from one to three carbon atoms; Z is selected from the group consisting of hydrogen, alkyl of from one to three carbon atoms, inclusive, alkoxy of from one to three carbon atoms, inclusive, fluoro, chloro, and bromo.
Claim 12
Dependent Claim
53 words
Compounds of the formula ##STR53## wherein R is selected from the group consisting of, alkyl of from one to three carbon atoms; Z is selected from the group consisting of hydrogen, alkyl of from one to three carbon atoms, inclusive, alkoxy of from one to three carbon atoms, inclusive, fluoro, chloro, and bromo.
Claim 13
Dependent Claim
15 words
A compound in accordance with claim 10 wherein Z is chloro and R is ethyl.
Claim 14
Dependent Claim
17 words
A compound of the formula ##STR54## wherein R is alkyl of one to three carbon atoms, inclusive.
Claim 15
Dependent Claim
17 words
A compound of the formula ##STR54## wherein R is alkyl of one to three carbon atoms, inclusive.
Claim 16
Dependent Claim
11 words
A compound in accordance with claim 12 wherein R is ethyl.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-06-12 | 1981-12-12 | 1982-06-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-06-12 | 1985-12-12 | 1986-06-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-06-12 | 1989-12-12 | 1990-06-13 | $7700.00 | Window Closed / Lapsed |