US4430263A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Hapten-inhibitor immunoassay
Assignee: Abbott Laboratories
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Filing: 1980-01-21
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Granted: 1984-02-07
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Expires: 2000-01-21
Abstract
Abstract A specific binding assay method employing, as a labeling substance, a reversible trypsin inhibitor for the detection of a hapten. Competition between the hapten to be determined and hapten trysin inhibitor conjugate for antibody to the hapten, in the presence of enzyme, followed by addition of enzyme substrate provides an effective method for hapten analysis. The preferred trypsin inhibitor is a protein having a molecular weight range of 2,000-75,000. The preferred ratio of the hapten to the inhibitor in the conjugate is between 1:1 and 3:1.
Inventors
- 👤 Steven C. March
- 👤 John W. Safford, Jr.
- 👤 Susan E. Magic
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 11:19
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/531; G01N33/532; G01N33/536; G01N33/542
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
29 words
Hapten-trypsin inhibitor conjugate having 1-3 molecules of hapten per molecule of trypsin inhibitor wherein the trypsin inhibitor is a protein trypsin inhibitor having a molecular weight range of 2,000-75,000.
Claim 2
Dependent Claim
29 words
Hapten-trypsin inhibitor conjugate having 1-3 molecules of hapten per molecule of trypsin inhibitor wherein the trypsin inhibitor is a protein trypsin inhibitor having a molecular weight range of 2,000-75,000.
Claim 3
Dependent Claim
29 words
Thyroxine-trypsin inhibitor conjugate having 1-3 molecules of thyroxine per molecule of trypsin inhibitor wherein the trypsin inhibitor is a protein trypsin inhibitor having a molecular weight range of 2,000-75,000.
Claim 4
Dependent Claim
29 words
Thyroxine-trypsin inhibitor conjugate having 1-3 molecules of thyroxine per molecule of trypsin inhibitor wherein the trypsin inhibitor is a protein trypsin inhibitor having a molecular weight range of 2,000-75,000.
References Cited (Backward Citations)
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US3957342A
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US4065354A
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Cited
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Cited
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Cited
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Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-02-06 | 1987-08-08 | 1988-02-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-02-06 | 1991-08-08 | 1992-02-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-02-06 | 1995-08-08 | 1996-02-07 | $7700.00 | Window Closed / Lapsed |