Patent US4344938A successfully refreshed from Google Patents.
US4344938A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Agent for the treatment of allergic reactions
Assignee: Siemens Healthcare Diagnostics GmbH Germany
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Filing: 1979-10-23
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Granted: 1982-08-17
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Expires: 1999-10-23
Abstract
Abstract What are disclosed are a method for the prophylaxis and therapy of allergic reactions and an agent therefor, said agent containing immunoglobulins of class IgG or fragments thereof which have been immunologically modified in their Fc part.
Inventors
- 👤 Hans-Herald Sedlacek
- 👤 Friedrich R. Seiler
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 20:28
CPC Classifications
C; C07; C07K; C07K16/00; C07K16/06; C07K16/065; A; A61; A61P; A61P37/00; A61P37/08; A61K; A61K38/00; Y; Y10; Y10S; Y10S424/00; Y10S424/809; Y10S424/81; Y10S530/00; Y10S530/806; Y10S530/866; Y10S530/868
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
59 words
A pharmaceutical preparation for the prophylaxis or therapy of allergic reactions, said preparation comprising complex-fixed IgG immunoglobulin modified in the Fc-portion thereof by aggregation or immunological fixing to an antigen, or comprising immunologically active fragments of IgG immunoglobulin obtained by proteolytic fission of IgG immunoglobulin, said fragments being modified in the Fc-portion thereof, together with a pharmaceutically-acceptable carrier therefor.
Claim 2
Dependent Claim
59 words
A pharmaceutical preparation for the prophylaxis or therapy of allergic reactions, said preparation comprising complex-fixed IgG immunoglobulin modified in the Fc-portion thereof by aggregation or immunological fixing to an antigen, or comprising immunologically active fragments of IgG immunoglobulin obtained by proteolytic fission of IgG immunoglobulin, said fragments being modified in the Fc-portion thereof, together with a pharmaceutically-acceptable carrier therefor.
Claim 3
Dependent Claim
18 words
A pharmaceutical preparation as in claim 1 comprising complex-fixed IgG immunoglobulin wherein said complex-fixed IgG immunoglobulin is aggregated.
Claim 4
Dependent Claim
22 words
A pharmaceutical preparation as in claim 1 comprising complex-fixed IgG immunoglobulin wherein said complex-fixed IgG immunoglobulin is immunologically fixed to an antigen.
Claim 5
Dependent Claim
14 words
A pharmaceutical preparation as in claim 1 comprising immunologically active fragments of IgG immunoglobulin.
Claim 6
Dependent Claim
34 words
A pharmaceutical preparation as in claim 4 wherein said immunologically active fragments are obtained by proteolytic fission of IgG immunoglobulin with an enzyme selected from the group consisting of papain, plasmin, pepsin, and trypsin.
Claim 7
Independent Claim
74 words
A method for the prophylaxis or therapy of allergic reactions in a patient susceptible to or suffering therefrom, which method comprises locally, orally, or parenterally administering to said patient an anti-allergically effective amount of a complex-fixed IgG immunoglobulin modified in the Fc-portion thereof by aggregation or immunological fixing to an antigen, or of immunologically active fragments of IgG immunoglobulin obtained by proteolytic fission of IgG immunoglobulin, said fragments being modified in the Fc-portion thereof.
Claim 8
Independent Claim
74 words
A method for the prophylaxis or therapy of allergic reactions in a patient susceptible to or suffering therefrom, which method comprises locally, orally, or parenterally administering to said patient an anti-allergically effective amount of a complex-fixed IgG immunoglobulin modified in the Fc-portion thereof by aggregation or immunological fixing to an antigen, or of immunologically active fragments of IgG immunoglobulin obtained by proteolytic fission of IgG immunoglobulin, said fragments being modified in the Fc-portion thereof.
Claim 9
Dependent Claim
21 words
A method as in claim 6 wherein complex-fixed IgG immunoglobulin is administered, the Fc-portion of which has been modified by aggregation.
Claim 10
Dependent Claim
24 words
A method as in claim 6 wherein complex-fixed IgG immunoglobulin is administered, the Fc-portion of which has been modified by fixing to an antigen.
Claim 11
Dependent Claim
15 words
A method as in claim 6 wherein immunologically active fragments of IgG immunoglobulin are administered.
Claim 12
Dependent Claim
36 words
A method as in claim 6 wherein said immunologically active fragments of IgG immunoglobulin are obtained by proteolytic fission of IgG immunoglobulin with an enzyme selected from the group consisting of papain, plasma, pepsin, and trypsin.
References Cited (Backward Citations)
US4161522A
Cited
US4190646A
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US4164495A
Cited
US4107298A
Cited
US4190647A
Cited
US4256631A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-08-16 | 1986-02-15 | 1986-08-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-08-16 | 1990-02-15 | 1990-08-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-08-16 | 1994-02-15 | 1994-08-17 | $7700.00 | Window Closed / Lapsed |