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Stabilization of benzidine-type indicators with various enhancers

Assignee: Bayer Corp
•
Filing: 1981-07-23
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Granted: 1982-07-13
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Expires: 2001-07-23
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Abstract

Abstract An improved composition, device and method, whereby enhanced sensitivity is achieved in detecting test sample constituents such as glucose and blood. The improvement resides in the use of a broad range of compounds as enhancers for benzidine-type indicators. The enhancer tends to stabilize the blue color form of such indicators.

Inventors

  • 👤 Thomas A. Magers
  • 👤 David L. Tabb

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-29 22:09
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/54; C12Q1/26; C12Q1/28; C12Q2326/00; C12Q2326/10; C12Q2326/12; C12Q2326/14; Y; Y10; Y10T; Y10T436/00; Y10T436/14; Y10T436/142222; Y10T436/143333; Y10T436/15; Y10T436/153333

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 39 words
In a composition for detecting the presence of a constituent in a test sample, said composition comprising a benzidine-type indicator, the improvement wherein said composition additionally comprises an enhancer compound having the structure ##STR5## wherein R is lower alkyl.
Claim 2
Dependent Claim 39 words
In a composition for detecting the presence of a constituent in a test sample, said composition comprising a benzidine-type indicator, the improvement wherein said composition additionally comprises an enhancer compound having the structure ##STR5## wherein R is lower alkyl.
Claim 3
Dependent Claim 11 words
The composition of claim 1 in which said enhancer is 4-picoline.
Claim 4
Dependent Claim 29 words
A test device for determining the presence of a constituent in a test sample, said device comprising a carrier matrix incorporated with the composition of claim 1 or 2.
Claim 5
Dependent Claim 34 words
A method for determining the presence of a constituent in a test sample, said method comprising contacting said test sample with the improved composition of claim 1 or 2 and observing a detectable response.
Claim 6
Dependent Claim 31 words
A method for determining the presence of a constituent in a test sample, said method comprising contacting said test sample with the device of claim 3, and observing a detectable response.

References Cited (Backward Citations)

US3290228A Cited
US3853472A Cited
US3917452A Cited
US4089747A Cited
US4071321A Cited
US4148611A Cited
US4279993A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1985-07-12 1986-01-11 1986-07-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1989-07-12 1990-01-11 1990-07-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1993-07-12 1994-01-11 1994-07-13 $7700.00 Window Closed / Lapsed

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