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US4250170A
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US
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Antibacterial agents Bu-2349A and B and method of using same
Assignee: Bristol Myers Co
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Filing: 1979-06-11
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Granted: 1981-02-10
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Expires: 1999-06-11
Abstract
Abstract A novel water-soluble basic antibiotic complex designated herein as Bu-2349 is produced by fermentation of Bu-2349-producing strains of the genus Bacillus. Complex Bu-2349 and its bioactive components designated as Bu-2349A and B are found to possess marked inhibitory activity against gram-positive and gram-negative bacteria including various types of aminoglycoside-resistant bacteria.
Inventors
- 👤 Hiroshi Kawaguchi
- 👤 Masataka Konishi
- 👤 Takashi Tsuno
- 👤 Takeo Miyaki
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 05:09
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/203; C12; C12N; C12N1/00; C12N1/20; C12N1/205; C12P; C12P19/00; C12P19/44; C12R; C12R2001/00; C12R2001/01; C12R2001/07
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
15 words
The antibiotic Bu-2349A having the formula ##STR7## or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
15 words
The antibiotic Bu-2349A having the formula ##STR7## or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
10 words
The compound of claim 1 which is Bu-2349A free base.
Claim 4
Dependent Claim
9 words
The compound of claim 1 which is Bu-2349A hydrochloride.
Claim 5
Dependent Claim
9 words
The compound of claim 1 which is Bu-2349A carbonate.
Claim 6
Dependent Claim
15 words
The antibiotic Bu-2349B having the formula ##STR8## or a pharmaceutically acceptable acid addition salt thereof.
Claim 7
Dependent Claim
15 words
The antibiotic Bu-2349B having the formula ##STR8## or a pharmaceutically acceptable acid addition salt thereof.
Claim 8
Dependent Claim
10 words
The compound of claim 5 which is Bu-2349B free base.
Claim 9
Dependent Claim
9 words
The compound of claim 5 which is Bu-2349B hydrochloride.
Claim 10
Dependent Claim
9 words
The compound of claim 5 which is Bu-2349B carbonate.
Claim 11
Independent Claim
53 words
A method for inhibiting the growth of pathogenic bacteria in an animal which comprises parenterally administering to said animal an effective antibacterial amount of an antibiotic selected from the group consisting of Bu-2349A having the formula ##STR9## Bu-2349B having the formula ##STR10## and a pharmaceutically acceptable acid addition salt of Bu-2349A or B.
Claim 12
Independent Claim
53 words
A method for inhibiting the growth of pathogenic bacteria in an animal which comprises parenterally administering to said animal an effective antibacterial amount of an antibiotic selected from the group consisting of Bu-2349A having the formula ##STR9## Bu-2349B having the formula ##STR10## and a pharmaceutically acceptable acid addition salt of Bu-2349A or B.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-02-10 | 1984-08-11 | 1985-02-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-02-10 | 1988-08-11 | 1989-02-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-02-10 | 1992-08-11 | 1993-02-10 | $7700.00 | Window Closed / Lapsed |