Patent US4100274A successfully refreshed from Google Patents.
US4100274A
Expired / Lapsed
US
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Polypeptide
Assignee: Imperial Chemical Industries Ltd
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Filing: 1977-04-22
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Granted: 1978-07-11
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Expires: 1997-04-22
Abstract
Abstract The disclosure relates to novel luliberin analogues which possess luliberin agonist activity, to processes for their manufacture and to compositions containing them. Typical of the peptides disclosed is <IMAGE> in which A is D-Phe, D-Tyr(Me) or D-Ser(But).
Inventors
- 👤 Anand Swaroop Dutta
- 👤 Barrington John Albert Furr
- 👤 Michael Brian Giles
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 22:26
CPC Classifications
C; C07; C07K; C07K5/00; C07K5/04; C07K5/06; C07K5/06086; C07K5/06095; A; A61; A61P; A61P15/00; C07K7/00; C07K7/04; C07K7/23; A61K; A61K38/00; Y; Y10; Y10S; Y10S930/00; Y10S930/01; Y10S930/13
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
50 words
A polypeptide of the formula: ##STR8## in which A is selected from the group consisting of D-Tyr(Me), D-Ser(Bu t ) and D-Phe, B is selected from the group consisting of Leu or MeLeu, E is Azgly and F is an amino radical, and the pharmaceutically- and veterinarily-acceptable acid-addition salts thereof.
Claim 2
Dependent Claim
50 words
A polypeptide of the formula: ##STR8## in which A is selected from the group consisting of D-Tyr(Me), D-Ser(Bu t ) and D-Phe, B is selected from the group consisting of Leu or MeLeu, E is Azgly and F is an amino radical, and the pharmaceutically- and veterinarily-acceptable acid-addition salts thereof.
Claim 3
Dependent Claim
10 words
A polypeptide as claimed in claim 1 which is ##STR9##
Claim 4
Dependent Claim
10 words
A polypeptide as claimed in claim 1 which is ##STR10##
Claim 5
Dependent Claim
10 words
A polypeptide as claimed in claim 1 which is ##STR11##
Claim 6
Dependent Claim
35 words
A pharmaceutical or veterinary composition comprising as active ingredient an effective amount of a polypeptide as claimed in claim 1 in association with a major amount of a nontoxic pharmaceutically- or veterinarily-acceptible diluent or carrier.
Claim 7
Dependent Claim
25 words
A method of controlling and/or improving reproduction in warm-blooded animals which comprises administration of an effective amount of a polypeptide as claimed in claim 1.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-07-10 | 1982-01-09 | 1982-07-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-07-10 | 1986-01-09 | 1986-07-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-07-10 | 1990-01-09 | 1990-07-11 | $7700.00 | Window Closed / Lapsed |