US3896104A
Expired / Lapsed
US
⏱️ 0.0 years remaining
P-glu-his-trp-ser-tyr-d-lys-leu-arg-pro-gly-nh' 2 'and intermediates
Assignee: Wyeth LLC
•
Filing: 1974-05-22
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Granted: 1975-07-22
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Expires: 1994-05-22
Abstract
Abstract D-Lys6-LRF, is described as well as its synthesis by solid phase techniques and novel intermediates formed by such synthesis. This novel decapeptide stimulates the release of luteinizing hormone and is useful in mammals in increasing and regulating fertility.
Inventors
- 👤 Wayne A Mckinely
- 👤 Dimitrois Sarantakis
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 19:56
CPC Classifications
C; C07; C07K; C07K7/00; C07K7/04; C07K7/23; A; A61; A61K; A61K38/00; Y; Y10; Y10S; Y10S930/00; Y10S930/01; Y10S930/13; Y10S930/28
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
9 words
A COMPOUND SELECTED FROM THE CLASS CONSISTING OF L-PGLU-L-HIS-L-TRP-L-SER-L-TYR-D-LYS-L-LEU-L-AG-L-PROGLY-NH2
Claim 2
Dependent Claim
9 words
A COMPOUND SELECTED FROM THE CLASS CONSISTING OF L-PGLU-L-HIS-L-TRP-L-SER-L-TYR-D-LYS-L-LEU-L-AG-L-PROGLY-NH2
Claim 3
Dependent Claim
13 words
A compound according to formula II of claim 1 wherein X is NH2.
Claim 4
Dependent Claim
16 words
A compound according to formula II of claim 1 wherein R5 is hydrogen and X is
Claim 5
Dependent Claim
23 words
A compound according to claim 2 wherein R1 is tosyl, R2 is 2-chlorobenzyloxycarbonyl, R3 is 2,6-dichlorobenzyl, R4 is benzyl and R6 is tosyl.
Claim 6
Dependent Claim
18 words
A compound according to claim 1 which is selected from L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-lysyl-L-leucyl-L -arginyl-L-prolyl-glycinamide and its non-toxic acid addition salts.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-07-21 | 1979-01-20 | 1979-07-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-07-21 | 1983-01-20 | 1983-07-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-07-21 | 1987-01-20 | 1987-07-22 | $7700.00 | Window Closed / Lapsed |