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US3901872A Expired / Lapsed US ⏱️ 0.0 years remaining

P-glu-his-trp-ser-tyr-d-pgl-leu-arg-pro-gly-nh' 2 'and intermediates

Assignee: Wyeth LLC
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Filing: 1974-03-13
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Granted: 1975-08-26
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Expires: 1994-03-13
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Abstract

Abstract D-Pg16-LRF, is described as well as its synthesis by solid phase techniques and novel intermediates formed by such synthesis. This novel decapeptide stimulates the release of luteinizing hormone and is useful in mammals in increasing and regulating fertility.

Inventors

  • 👤 Wayne A Mckinley
  • 👤 Dimitrios Sarantakis

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 05:47
CPC Classifications
C; C07; C07K; C07K7/00; C07K7/04; C07K7/23; A; A61; A61K; A61K38/00; Y; Y10; Y10S; Y10S930/00; Y10S930/01; Y10S930/13; Y10S930/28

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 13 words
A compound according to formula II of claim 1 wherein X is NH2.
Claim 2
Dependent Claim 16 words
A compound according to formula II of claim 1 wherein R4 is hydrogen and X is
Claim 3
Dependent Claim 20 words
A compound according to claim 3 wherein R1 is tosyl, R2 is dichlorobenzyl, R3 is benzyl and R5 is tosyl.
Claim 4
Dependent Claim 18 words
A compound accOrding to claim 1 which is selected from L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-C-phenylglycyl-L -leucyl-L-arginyl-L-prolyl-glycinamide and its non-toxic acid addition salts.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-08-25 1979-02-24 1979-08-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-08-25 1983-02-24 1983-08-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-08-25 1987-02-24 1987-08-26 $7700.00 Window Closed / Lapsed

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