Inorganic salts of dipeptide sweeteners

Claim 2

An artificially sweetened foodstuff comprising a foodstuff and a dry dipeptide salt sweetener selected from the formula ##STR6## wherein: The stereochemical configuration is DL--DL, DL-L, L-DL or L--L; when R 1 is hydrogen, R is H 3 SO 4 + , H 4 PO 4 + , or H 2 NO 3 +; n represents an integer of 0 to 5; where R hydrogen, R 1 is sodium, potassium, calcium, or ammonium; R 3 represents lower alkyl, lower alkylaryl and cycloalkyl; R 2 represents a. lower alkyl b. a substituted or unsubstituted, partially saturated or totally saturated six carbon ring provided that when substituted, the substituent is at the four position and is hydroxy, lower alkoxy, lower alkyl or halogen; and c. S(O) m (lower alkyl) provided that n is 1 or 2 and m is 0, or 2, said dry dipeptide salt sweetener being present in an amount effective to sweeten the foodstuff, said dipeptide salt being faster to dissolve than the corresponding unsubstituted dipeptide sweetener.

Claim 3

The foodstuff of claim 1 wherein: n represents 0 or 1; R represents H 4 PO 4 +; R 1 is hydrogen; R 3 represents lower alkyl; and R 2 represents phenyl, cyclohexyl, benzyl, 1,4-cyclohexadienyl or 1-cyclohexenyl.

Claim 4

The foodstuff of claim 2 wherein the sweetener is L-aspartyl-L-phenylalanine methyl ester dihydrogen phosphate.

Claim 5

The foodstuff of claim 1 wherein: n represents 0 or 1; R is hydrogen; R 1 is sodium; R 3 represents lower alkyl; and R 2 represents phenyl, cyclohexyl, benzyl, 1,4-cyclohexadienyl or 1-cyclohexenyl.

Claim 6

The foodstuff of claim 4 wherein the sweetener is sodium L-aspartyl-L-phenylalanine methyl ester.

Claim 9

The method of claim 6 wherein the sweetener is L-aspartyl-L-phenylalanine methyl ester dihydrogen phosphate.

Claim 10

The method of claim 6 wherein the sweetener is sodium L-aspartyl-L-phenylalanine methyl ester.

Claim 11

A dry sweetening composition comprising an edible carrier and a dipeptide salt sweetener selected from the formula: ##STR8## wherein: The stereochemical configuration is DL--DL, DL-L, L-DL or L--L; when R 1 is hydrogen, R is H 3 SO 4 + , H 4 PO 4 + , or H 2 NO 3 +; n represents an integer of 0 to 5; where R hydrogen, R 1 is sodium, potassium, calcium or ammonium; R 3 represents lower alkyl, lower alkylaryl and cycloalkyl; R 2 represents a. lower alkyl b. a substituted or unsubstituted, partially saturated or totally saturated six carbon ring provided that when substituted, the substituent is at the four position and is hydroxy, lower alkoxy, lower alkyl or halogen; and c. S(O) m (lower alkyl) provided that n is 1 or 2 and m is 0, or 2. said sweetener being encased in a major amount of a dry, edible carrier, said carrier being selected from the group consisting of hydrophilic colloids not having free amine groups, water dispersible dextrins, partially hydrolyzed starches, sugars, polyhydric alcohols, and mixtures thereof.

Claim 12

A dry sweetening composition comprising an edible carrier and a dipeptide salt sweetener selected from the formula: ##STR8## wherein: The stereochemical configuration is DL--DL, DL-L, L-DL or L--L; when R 1 is hydrogen, R is H 3 SO 4 + , H 4 PO 4 + , or H 2 NO 3 +; n represents an integer of 0 to 5; where R hydrogen, R 1 is sodium, potassium, calcium or ammonium; R 3 represents lower alkyl, lower alkylaryl and cycloalkyl; R 2 represents a. lower alkyl b. a substituted or unsubstituted, partially saturated or totally saturated six carbon ring provided that when substituted, the substituent is at the four position and is hydroxy, lower alkoxy, lower alkyl or halogen; and c. S(O) m (lower alkyl) provided that n is 1 or 2 and m is 0, or 2. said sweetener being encased in a major amount of a dry, edible carrier, said carrier being selected from the group consisting of hydrophilic colloids not having free amine groups, water dispersible dextrins, partially hydrolyzed starches, sugars, polyhydric alcohols, and mixtures thereof.

Claim 13

The composition of claim 9 wherein the sweetener is L-aspartyl-L-phenylalanine methyl ester dihydrogen phosphate.

Claim 14

The composition of claim 9 wherein the carrier is a non-hygroscopic carbohydrate.

Claim 15

The composition of claim 9 wherein the sweetener is sodium L-aspartyl-L-phenylalanine methyl ester.

Claim 16

The composition of claim 9 wherein the sweetener is L-aspartyl-L-cyclohexylalanine methyl ester dihydrogen phosphate.

Claim 17

The composition of claim 9 wherein the sweetener is sodium L-aspartyl-L-cyclohexylalanine methyl ester.

Claim 18

A dry salt of a dipeptide sweetener selected from the formula ##STR9## wherein: the stereochemical configuration is DL-DL, DL-L, L-DL, or L-L; n represents an integer of 0 to 5; Where R is hydrogen, R 1 is sodium, potassium, calcium or ammonium; Where R 1 is hydrogen, R is H 3 SO 4 + , H 4 PO 4 + , or H 2 NO 3 + R 3 represents lower alkyl, lower alkylaryl and cycloalkyl; R 2 represents a. lower alkyl b. a substituted or unsubstituted, partially saturated or totally saturated six carbon ring provided that when substituted, the substituent is at the four position and is hydroxy, lower alkoxy, lower alkyl or halogen; and c. S(O) m (lower alkyl) provided that n is 1 or 2 and m is 0, 1, or 2.

Claim 19

A dry salt of a dipeptide sweetener selected from the formula ##STR9## wherein: the stereochemical configuration is DL-DL, DL-L, L-DL, or L-L; n represents an integer of 0 to 5; Where R is hydrogen, R 1 is sodium, potassium, calcium or ammonium; Where R 1 is hydrogen, R is H 3 SO 4 + , H 4 PO 4 + , or H 2 NO 3 + R 3 represents lower alkyl, lower alkylaryl and cycloalkyl; R 2 represents a. lower alkyl b. a substituted or unsubstituted, partially saturated or totally saturated six carbon ring provided that when substituted, the substituent is at the four position and is hydroxy, lower alkoxy, lower alkyl or halogen; and c. S(O) m (lower alkyl) provided that n is 1 or 2 and m is 0, 1, or 2.

Claim 20

A dry salt of claim 15 wherein: n represents 0 or 1 R 3 represents lower alkyl; and R 2 represents phenyl, cyclohexyl, benzyl, 1, 4-cyclohexadienyl or 1-cyclohexenyl.

Claim 21

An L-aspartyl-L-phenylalanine methyl ester inorganic salt of claim 15.

Claim 22

The dihydrogen phosphate salt of claim 17.

Claim 23

The sodium salt of claim 17.