PROCESS FOR FACILITATING THE FORMATION OF LIPID SPHERULES DISPERSION IN AN AQUEOUS PHASE AND FOR IMPROVING THEIR STABILITY AND THEIR ENCAPSULATION RATE, AND CORRESPONDING DISPERSIONS.

Abstract

Abstract Translated from French CE PROCEDE PERMET DE FACILITER LA FORMATION DES SPHERULES LIPIDIQUES EN DISPERSION DANS UN MILIEU AQUEUX D ET D'AMELIORER SIMULTANEMENT LA STABILITE ET LE TAUX D'ENCAPSULATION DESDITES SPHERULES LIPIDIQUES, CELLES-CI ETANT CONSTITUEES DE FEUILLETS LIPIDIQUES SENSIBLEMENT CONCENTRIQUES ENCAPSULANT ENTRE EUX UNE PHASE AQUEUSE E, LES LIPIDES CONSTITUTIFS DES FEUILLETS ETANT DES AMPHIPHILES IONIQUES OU NON IONIQUES. A CET EFFET, AVANT LA FORMATION DESDITES SPHERULES, ON AJOUTE AUX LIPIDES DESTINES A CONSTITUER LES FEUILLETS DES SPHERULES, DU CHOLESTEROL SULFATE, A RAISON DE 1 A 50 EN POIDS PAR RAPPORT AU POIDS TOTAL DE LA PHASE LIPIDIQUE. THIS PROCESS ENABLES TO FACILITATE THE FORMATION OF LIPID SPHERULES IN DISPERSION IN AN AQUEOUS MEDIUM D AND SIMULTANEOUSLY IMPROVE THE STABILITY AND THE ENCAPSULATION RATE OF THE SAID LIPID SPHERULES, THESE CONSTITUTING SHEETS IN A CONCENTRATED LIPIDIC LIPIDIC CONCENTRATED SHEETS E, THE LIPIDS CONSTITUENTS OF THE SHEETS BEING IONIC OR NON-IONIC AMPHIPHILS. TO THIS END, BEFORE THE FORMATION OF THE SAID SPHERULES, CHOLESTEROL SULPHATE IS ADDED TO THE LIPIDS INTENDED TO CONSTITUTE THE LEAVES OF THE SPHERULES, AT A RATIO OF 1 TO 50 IN WEIGHT IN RELATION TO THE TOTAL WEIGHT OF THE LIPID PHASE.

Inventors

• 👤 Rose-Marie Handjani
• 👤 Nee Vila
• 👤 Alain Ribier
• 👤 Guy Vanlerberghe

Bibliographic Details