US7166097B2
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Cerebral perfusion augmentation
Assignee: Zoll Circulation Inc
•
Filing: 2004-09-22
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Granted: 2007-01-23
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Expires: 2024-09-22
Abstract
Abstract Methods are provided for partial aortic occlusion for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. The descending aorta is accessed. A device is then located downstream from the takeoff of the brachiocephalic artery. The device is operated to at least partially obstruct blood flow in the aorta during systole and diastole. A physiologic parameter can be measured. The device can then be adjusted to modify the degree of obstruction based on the measured physiologic parameter.
Inventors
- 👤 Denise R. Barbut
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:38
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/0067; A61M25/0082; A61B; A61B17/00; A61B17/12; A61B17/12022; A61B17/12027; A61B17/12036; A61B17/12099; A61B17/12109; A61B17/12131; A61B17/12136; A61B17/12168; A61B17/12172; A61B5/00; A61B5/02; A61B5/021; A61B5/0215; A61B5/40; A61B5/4076; A61B5/4058; A61B5/4064; A61M25/0068; A61M2025/0073; A61M25/10; A61M2025/1043; A61M2025/1052; A61M2210/00; A61M2210/12; A61M2210/127; A61M2230/00; A61M2230/30; A61M25/0074; A61M25/01; A61M25/06; A61M25/0662
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
78 words
A method for increasing cerebral blood flow, comprising the steps of: advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region; locating the expandable member in the abdominal aorta; expanding the expandable member to partially obstruct blood flow in the aorta during systole and diastole; measuring a physiologic parameter; and adjusting the expansion of the expandable member based on the measured physiologic parameter.
Claim 2
Independent Claim
78 words
A method for increasing cerebral blood flow, comprising the steps of: advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region; locating the expandable member in the abdominal aorta; expanding the expandable member to partially obstruct blood flow in the aorta during systole and diastole; measuring a physiologic parameter; and adjusting the expansion of the expandable member based on the measured physiologic parameter.
Claim 3
Dependent Claim
13 words
The method of claim 1 , wherein the physiologic parameter is blood pressure.
Claim 4
Dependent Claim
14 words
The method of claim 1 , wherein the physiologic parameter is cerebral blood flow.
Claim 5
Dependent Claim
13 words
The method of claim 1 , wherein the expandable member is a balloon.
Claim 6
Dependent Claim
18 words
The method of claim 1 , wherein blood flow to the cerebral vasculature increases by at least 20%.
Claim 7
Independent Claim
80 words
A method for increasing cerebral blood flow, comprising the steps of: advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region; locating the expandable member in the abdominal or thoracic aorta; expanding the expandable member to partially obstruct blood flow in the aorta during systole and diastole; measuring a physiologic parameter; and adjusting the expansion of the expandable member based on the measured physiologic parameter.
Claim 8
Independent Claim
80 words
A method for increasing cerebral blood flow, comprising the steps of: advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region; locating the expandable member in the abdominal or thoracic aorta; expanding the expandable member to partially obstruct blood flow in the aorta during systole and diastole; measuring a physiologic parameter; and adjusting the expansion of the expandable member based on the measured physiologic parameter.
Claim 9
Dependent Claim
13 words
The method of claim 6 , wherein the physiologic parameter is blood pressure.
Claim 10
Dependent Claim
14 words
The method of claim 6 , wherein the physiologic parameter is cerebral blood flow.
Claim 11
Dependent Claim
13 words
The method of claim 6 , wherein the expandable member is a balloon.
Claim 12
Dependent Claim
18 words
The method of claim 6 , wherein blood flow to the cerebral vasculature increases by at least 20%.
Claim 13
Independent Claim
81 words
A method for increasing cerebral blood flow, comprising the steps of: advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region; locating the expandable member in the aorta inferior to the heart; expanding the expandable member to partially obstruct blood flow in the aorta during systole and diastole; measuring a physiologic parameter; and adjusting the expansion of the expandable member based on the measured physiologic parameter.
Claim 14
Independent Claim
81 words
A method for increasing cerebral blood flow, comprising the steps of: advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region; locating the expandable member in the aorta inferior to the heart; expanding the expandable member to partially obstruct blood flow in the aorta during systole and diastole; measuring a physiologic parameter; and adjusting the expansion of the expandable member based on the measured physiologic parameter.
Claim 15
Dependent Claim
13 words
The method of claim 11 , wherein the physiologic parameter is blood pressure.
Claim 16
Dependent Claim
14 words
The method of claim 11 , wherein the physiologic parameter is cerebral blood flow.
Claim 17
Dependent Claim
13 words
The method of claim 11 , wherein the expandable member is a balloon.
Claim 18
Dependent Claim
18 words
The method of claim 11 , wherein blood flow to the cerebral vasculature increases by at least 20%.
Claim 19
Independent Claim
86 words
A method for increasing cerebral blood flow, comprising the steps of: advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region; locating the expandable member in the descending aorta; expanding the expandable member to partially obstruct blood flow in the aorta during systole and diastole for a sustained period without occluding the aorta; measuring a physiologic parameter; and adjusting the expansion of the expandable member based on the measured physiologic parameter.
Claim 20
Independent Claim
86 words
A method for increasing cerebral blood flow, comprising the steps of: advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region; locating the expandable member in the descending aorta; expanding the expandable member to partially obstruct blood flow in the aorta during systole and diastole for a sustained period without occluding the aorta; measuring a physiologic parameter; and adjusting the expansion of the expandable member based on the measured physiologic parameter.
Claim 21
Dependent Claim
13 words
The method of claim 16 , wherein the physiologic parameter is blood pressure.
Claim 22
Dependent Claim
14 words
The method of claim 16 , wherein the physiologic parameter is cerebral blood flow.
Claim 23
Dependent Claim
13 words
The method of claim 16 , wherein the expandable member is a balloon.
Claim 24
Dependent Claim
18 words
The method of claim 16 , wherein blood flow to the cerebral vasculature increases by at least 20%.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2010-01-22 | 2010-07-24 | 2011-01-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2014-01-22 | 2014-07-24 | 2015-01-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2018-01-22 | 2018-07-24 | 2019-01-23 | $7700.00 | Window Closed / Lapsed |