US7125421B2
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method and apparatus for valve repair
Assignee: Mitral Interventions Inc
•
Filing: 2002-08-30
•
Granted: 2006-10-24
•
Expires: 2022-08-30
Abstract
Abstract A tissue connection device is provided for use on a patient at a treatment site. The device comprises an elongate member having a distal end and a proximal end. The elongate member has a first, substantially linear configuration during delivery through an elongate delivery device, wherein the first configuration is sufficient to allow said member to be delivered percutaneously into the patient to the treatment site. The elongate member has a second, substantially circular configuration when said member disengages from the delivery device, wherein the second configuration is sufficient to support tissue at the treatment site. The elongate member in the second configuration defines a single ring.
Inventors
- 👤 William S. Tremulis
- 👤 Mahmood K. Razavi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:32
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/24; A61F2/2442; A61F2/2445; A61F2230/00; A61F2230/0063; A61F2230/0091
Claims Analysis
Total Claims: 87
Claim 1
Independent Claim
176 words
A tissue connecting device for use with an elongate delivery device on tissue at a target site, the device comprising: an elongate member deliverable to the target site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with said delivery device and a second substantially circular configuration defining a first support ring and a second support ring when removed from the delivery device; wherein the elongate member has a first support ring radial thickness different from a second support ring radial thickness, said first support ring configured to abut against one side of the target tissue and said second support ring configured to abut against an opposite side of the target tissue to thereby capture a portion of the target tissue therebetween; at least one suture coupled to the elongate member; and wherein said first support ring is coupled to said second ring via a wire extending radially towards the center of the two rings in a manner sufficient to pass through a non-tissue center of the targeted valve.
Claim 2
Dependent Claim
176 words
A tissue connecting device for use with an elongate delivery device on tissue at a target site, the device comprising: an elongate member deliverable to the target site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with said delivery device and a second substantially circular configuration defining a first support ring and a second support ring when removed from the delivery device; wherein the elongate member has a first support ring radial thickness different from a second support ring radial thickness, said first support ring configured to abut against one side of the target tissue and said second support ring configured to abut against an opposite side of the target tissue to thereby capture a portion of the target tissue therebetween; at least one suture coupled to the elongate member; and wherein said first support ring is coupled to said second ring via a wire extending radially towards the center of the two rings in a manner sufficient to pass through a non-tissue center of the targeted valve.
Claim 3
Dependent Claim
146 words
A tissue connecting device for use with an elongate delivery device on tissue at a target site, the device comprising: an elongate member deliverable to the target site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with said delivery device and a second substantially circular configuration defining a first support ring and a second support ring when removed from the delivery device; wherein the elongate member has a first support ring radial thickness different from a second support ring radial thickness, said first support ring configured to abut against one side of the target tissue and said second support ring configured to abut against an opposite side of the target tissue to thereby capture a portion of the target tissue therebetween; at least one suture coupled to the elongate member; and wherein said delivery device comprises a catheter.
Claim 4
Dependent Claim
146 words
A tissue connecting device for use with an elongate delivery device on tissue at a target site, the device comprising: an elongate member deliverable to the target site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with said delivery device and a second substantially circular configuration defining a first support ring and a second support ring when removed from the delivery device; wherein the elongate member has a first support ring radial thickness different from a second support ring radial thickness, said first support ring configured to abut against one side of the target tissue and said second support ring configured to abut against an opposite side of the target tissue to thereby capture a portion of the target tissue therebetween; at least one suture coupled to the elongate member; and wherein said delivery device comprises a catheter.
Claim 5
Dependent Claim
178 words
A tissue connecting device for use with an elongate delivery device on tissue at a target site, the device comprising: an elongate member deliverable to the target site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with said delivery device and a second substantially circular configuration defining a first support ring and a second support ring when removed from the delivery device; wherein the elongate member has a first support ring radial thickness different from a second support ring radial thickness, said first support ring configured to abut against one side of the target tissue and said second support ring configured to abut against an opposite side of the target tissue to thereby capture a portion of the target tissue therebetween at least one detachable suture removably coupled to the elongate member and wherein said first support ring is coupled to said second ring via a wire extending radially towards the center of the two rings in a manner sufficient to pass through a non-tissue center of the targeted valve.
Claim 6
Dependent Claim
178 words
A tissue connecting device for use with an elongate delivery device on tissue at a target site, the device comprising: an elongate member deliverable to the target site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with said delivery device and a second substantially circular configuration defining a first support ring and a second support ring when removed from the delivery device; wherein the elongate member has a first support ring radial thickness different from a second support ring radial thickness, said first support ring configured to abut against one side of the target tissue and said second support ring configured to abut against an opposite side of the target tissue to thereby capture a portion of the target tissue therebetween at least one detachable suture removably coupled to the elongate member and wherein said first support ring is coupled to said second ring via a wire extending radially towards the center of the two rings in a manner sufficient to pass through a non-tissue center of the targeted valve.
Claim 7
Dependent Claim
152 words
A tissue connection device for use with an elongate delivery device and at least one suture on tissue at a treatment site in a patient, the device comprising: an elongate member deliverable to a target tissue site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with the elongate delivery device and a second relaxed configuration defining a first support ring and a second support ring when removed from the elongate delivery device; said elongate member in said circular configuration shaped to have a distance between a first ring tissue engaging surface and a second ring tissue engaging surface; at least one suture coupled to said elongate member for seating said member against the treatment site; and wherein said suture reduces said distance therebetween and increases clamp force on any tissue between said first ring tissue engaging surface and the second ring tissue engaging surface.
Claim 8
Dependent Claim
152 words
A tissue connection device for use with an elongate delivery device and at least one suture on tissue at a treatment site in a patient, the device comprising: an elongate member deliverable to a target tissue site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with the elongate delivery device and a second relaxed configuration defining a first support ring and a second support ring when removed from the elongate delivery device; said elongate member in said circular configuration shaped to have a distance between a first ring tissue engaging surface and a second ring tissue engaging surface; at least one suture coupled to said elongate member for seating said member against the treatment site; and wherein said suture reduces said distance therebetween and increases clamp force on any tissue between said first ring tissue engaging surface and the second ring tissue engaging surface.
Claim 9
Dependent Claim
12 words
The device of claim 4 wherein the elongate member is deliverable percutaneously.
Claim 10
Dependent Claim
33 words
The device of claim 4 wherein the elongate member has a reduced stiffness wherein said first ring and said second ring reduce valve dilation of tissue therebetween only with use of said suture.
Claim 11
Dependent Claim
16 words
The device of claim 4 wherein the elongate member is deliverable to engage a heart valve.
Claim 12
Dependent Claim
19 words
The device of claim 4 wherein the first support ring radial thickness greater than said second ring radial thickness.
Claim 13
Dependent Claim
40 words
The device of claim 4 wherein at least an outer portion of the first support ring comprises a material selected from one of the following: a nickel titanium alloy, superelastic metallic alloys, superelastic plastic, PTFE, silicone, stainless steel, and ceramic.
Claim 14
Dependent Claim
13 words
The device of claim 4 wherein said elongate member comprises a shape-memory material.
Claim 15
Dependent Claim
24 words
The device of claim 4 wherein said elongate member comprises a material allowing for penetration by a suture needle to attach a suture therein.
Claim 16
Dependent Claim
28 words
The device of claim 4 wherein said elongate member has an outer layer comprising a material allowing for penetration by a suture needle to attach a suture therein.
Claim 17
Dependent Claim
24 words
The device of claim 4 further comprising a plurality of apertures on said first ring sufficient for attachment of sutures to the first ring.
Claim 18
Dependent Claim
17 words
The device of claim 4 wherein first support ring has a surface suitable for engagement by sutures.
Claim 19
Dependent Claim
17 words
The device of claim 4 wherein said elongate member comprises a material suitable for penetration by sutures.
Claim 20
Dependent Claim
13 words
The device of claim 4 wherein first support ring has a mesh cover.
Claim 21
Dependent Claim
14 words
The device of claim 4 wherein the first support ring has a Dacron® covering.
Claim 22
Dependent Claim
28 words
The device of claim 4 further comprising a plurality of anchoring locations on said first support ring sufficient to allow for attachment of sutures to the first ring.
Claim 23
Dependent Claim
16 words
The device of claim 4 further comprising at least one suture coupled to the elongate member.
Claim 24
Dependent Claim
18 words
The device of claim 4 further comprising at least one detachable suture removably coupled to the elongate member.
Claim 25
Dependent Claim
15 words
The device of claim 4 wherein said elongate member includes at least one radiopaque marker.
Claim 26
Dependent Claim
27 words
The device of claim 4 wherein said distal end is spaced apart from said proximal end when said elongate member is in the first, substantially linear configuration.
Claim 27
Dependent Claim
20 words
The device of claim 4 wherein said first support ring and said second support ring define an overlapping coil configuration.
Claim 28
Dependent Claim
23 words
The device of claim 23 wherein said first support ring is configured to engage an inner circumferential surface of the second support ring.
Claim 29
Dependent Claim
21 words
The device of claim 4 wherein said first support ring is in a plane parallel to a second support ring plane.
Claim 30
Dependent Claim
25 words
The device of claim 4 wherein said elongate member is configured to connect the first ring to the second ring without penetrating said target tissue.
Claim 31
Dependent Claim
12 words
The device of claim 4 wherein said delivery device comprises a catheter.
Claim 32
Dependent Claim
152 words
A tissue connection device for use with an elongate delivery device and at least one suture on tissue at a treatment site in a patient, the device comprising: an elongate member deliverable to a target tissue site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with the elongate delivery device and a second relaxed configuration defining a first support ring and a second support ring when removed from the elongate delivery device; said elongate member in said circular configuration shaped to have a distance between a first ring tissue engaging surface and a second ring tissue engaging surface; at least one suture coupled to said elongate member for seating said member against the treatment site; and wherein the elongate member has a reduced stiffness wherein said first ring and said second ring reduce valve dilation of tissue therebetween only with use of said suture.
Claim 33
Dependent Claim
152 words
A tissue connection device for use with an elongate delivery device and at least one suture on tissue at a treatment site in a patient, the device comprising: an elongate member deliverable to a target tissue site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with the elongate delivery device and a second relaxed configuration defining a first support ring and a second support ring when removed from the elongate delivery device; said elongate member in said circular configuration shaped to have a distance between a first ring tissue engaging surface and a second ring tissue engaging surface; at least one suture coupled to said elongate member for seating said member against the treatment site; and wherein the elongate member has a reduced stiffness wherein said first ring and said second ring reduce valve dilation of tissue therebetween only with use of said suture.
Claim 34
Dependent Claim
33 words
The device of claim 28 wherein said suture reduces said distance therebetween and increases clamp force on any tissue between said first ring tissue engaging surface and the second ring tissue engaging surface.
Claim 35
Dependent Claim
12 words
The device of claim 28 wherein the elongate member is deliverable percutaneously.
Claim 36
Dependent Claim
16 words
The device of claim 28 wherein the elongate member is deliverable to engage a heart valve.
Claim 37
Dependent Claim
19 words
The device of claim 28 wherein the first support ring radial thickness greater than said second ring radial thickness.
Claim 38
Dependent Claim
40 words
The device of claim 28 wherein at least an outer portion of the first support ring comprises a material selected from one of the following: a nickel titanium alloy, superelastic metallic alloys, superelastic plastic; PTFE, silicone, stainless steel, and ceramic.
Claim 39
Dependent Claim
13 words
The device of claim 28 wherein said elongate member comprises a shape-memory material.
Claim 40
Dependent Claim
24 words
The device of claim 28 wherein said elongate member comprises a material allowing for penetration by a suture needle to attach a suture therein.
Claim 41
Dependent Claim
28 words
The device of claim 28 wherein said elongate member has an outer layer comprising a material allowing for penetration by a suture needle to attach a suture therein.
Claim 42
Dependent Claim
24 words
The device of claim 28 further comprising a plurality of apertures on said first ring sufficient for attachment of sutures to the first ring.
Claim 43
Dependent Claim
17 words
The device of claim 28 wherein first support ring has a surface suitable for engagement by sutures.
Claim 44
Dependent Claim
17 words
The device of claim 28 wherein said elongate member comprises a material suitable for penetration by sutures.
Claim 45
Dependent Claim
13 words
The device of claim 28 wherein first support ring has a mesh cover.
Claim 46
Dependent Claim
14 words
The device of claim 28 wherein the first support ring has a Dacron® covering.
Claim 47
Dependent Claim
28 words
The device of claim 28 further comprising a plurality of anchoring locations on said first support ring sufficient to allow for attachment of sutures to the first ring.
Claim 48
Dependent Claim
16 words
The device of claim 28 further comprising at least one suture coupled to the elongate member.
Claim 49
Dependent Claim
18 words
The device of claim 28 further comprising at least one detachable suture removably coupled to the elongate member.
Claim 50
Dependent Claim
15 words
The device of claim 28 wherein said elongate member includes at least one radiopaque marker.
Claim 51
Dependent Claim
27 words
The device of claim 28 wherein said distal end is spaced apart from said proximal end when said elongate member is in the first, substantially linear configuration.
Claim 52
Dependent Claim
20 words
The device of claim 28 wherein said first support ring and said second support ring define an overlapping coil configuration.
Claim 53
Dependent Claim
23 words
The device of claim 47 wherein said first support ring is configured to engage an inner circumferential surface of the second support ring.
Claim 54
Dependent Claim
21 words
The device of claim 28 wherein said first support ring is in a plane parallel to a second support ring plane.
Claim 55
Dependent Claim
25 words
The device of claim 28 wherein said elongate member is configured to connect the first ring to the second ring without penetrating said target tissue.
Claim 56
Dependent Claim
12 words
The device of claim 28 wherein said delivery device comprises a catheter.
Claim 57
Dependent Claim
142 words
A tissue connection device for use with an elongate delivery device and at least one suture on tissue at a treatment site in a patient, the device comprising: an elongate member deliverable to a target tissue site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with the elongate delivery device and a second relaxed configuration defining a first support ring and a second support ring when removed from the elongate delivery device; said elongate member in said circular configuration shaped to have a distance between a first ring tissue engaging surface and a second ring tissue engaging surface; at least one suture coupled to said elongate member for seating said member against the treatment site; and a plurality of apertures on said first ring sufficient for attachment of sutures to the first support ring.
Claim 58
Dependent Claim
142 words
A tissue connection device for use with an elongate delivery device and at least one suture on tissue at a treatment site in a patient, the device comprising: an elongate member deliverable to a target tissue site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with the elongate delivery device and a second relaxed configuration defining a first support ring and a second support ring when removed from the elongate delivery device; said elongate member in said circular configuration shaped to have a distance between a first ring tissue engaging surface and a second ring tissue engaging surface; at least one suture coupled to said elongate member for seating said member against the treatment site; and a plurality of apertures on said first ring sufficient for attachment of sutures to the first support ring.
Claim 59
Dependent Claim
33 words
The device of claim 52 wherein said suture reduces said distance therebetween and increases clamp force on any tissue between said first ring tissue engaging surface and the second ring tissue engaging surface.
Claim 60
Dependent Claim
12 words
The device of claim 52 wherein the elongate member is deliverable percutaneously.
Claim 61
Dependent Claim
33 words
The device of claim 52 wherein the elongate member has a reduced stiffness wherein said first ring and said second ring reduce valve dilation of tissue therebetween only with use of said suture.
Claim 62
Dependent Claim
16 words
The device of claim 52 wherein the elongate member is deliverable to engage a heart valve.
Claim 63
Dependent Claim
19 words
The device of claim 52 wherein the first support ring radial thickness greater than said second ring radial thickness.
Claim 64
Dependent Claim
40 words
The device of claim 52 wherein at least an outer portion of the first support ring comprises a material selected from one of the following: a nickel titanium alloy, superelastic metallic alloys, superelastic plastic, PTFE, silicone, stainless steel, and ceramic.
Claim 65
Dependent Claim
13 words
The device of claim 52 wherein said elongate member comprises a shape-memory material.
Claim 66
Dependent Claim
24 words
The device of claim 52 wherein said elongate member comprises a material allowing for penetration by a suture needle to attach a suture therein.
Claim 67
Dependent Claim
28 words
The device of claim 52 wherein said elongate member has an outer layer comprising a material allowing for penetration by a suture needle to attach a suture therein.
Claim 68
Dependent Claim
17 words
The device of claim 52 wherein first support ring has a surface suitable for engagement by sutures.
Claim 69
Dependent Claim
17 words
The device of claim 52 wherein said elongate member comprises a material suitable for penetration by sutures.
Claim 70
Dependent Claim
13 words
The device of claim 52 wherein first support ring has a mesh cover.
Claim 71
Dependent Claim
14 words
The device of claim 52 wherein the first support ring has a Dacron® covering.
Claim 72
Dependent Claim
28 words
The device of claim 52 further comprising a plurality of anchoring locations on said first support ring sufficient to allow for attachment of sutures to the first ring.
Claim 73
Dependent Claim
16 words
The device of claim 52 further comprising at least one suture coupled to the elongate member.
Claim 74
Dependent Claim
18 words
The device of claim 52 further comprising at least one detachable suture removably coupled to the elongate member.
Claim 75
Dependent Claim
15 words
The device of claim 52 wherein said elongate member includes at least one radiopaque marker.
Claim 76
Dependent Claim
27 words
The device of claim 52 wherein said distal end is spaced apart from said proximal end when said elongate member is in the first, substantially linear configuration.
Claim 77
Dependent Claim
20 words
The device of claim 52 wherein said first support ring and said second support ring define an overlapping coil configuration.
Claim 78
Dependent Claim
23 words
The device of claim 71 wherein said first support ring is configured to engage an inner circumferential surface of the second support ring.
Claim 79
Dependent Claim
21 words
The device of claim 52 wherein said first support ring is in a plane parallel to a second support ring plane.
Claim 80
Dependent Claim
25 words
The device of claim 52 wherein said elongate member is configured to connect the first ring to the second ring without penetrating said target tissue.
Claim 81
Dependent Claim
42 words
The device of claim 52 wherein said first support ring is coupled to said second ring via a wire extending radially towards the center of the two rings in a manner sufficient to pass through a non-tissue center of the targeted valve.
Claim 82
Dependent Claim
25 words
The device of claim 52 wherein said elongate member is configured to connect the first ring to the second ring without penetrating said target tissue.
Claim 83
Dependent Claim
12 words
The device of claim 52 wherein said delivery device comprises a catheter.
Claim 84
Dependent Claim
152 words
A tissue connection device for use with an elongate delivery device and at least one suture on tissue at a treatment site in a patient, the device comprising: an elongate member deliverable to a target tissue site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with the elongate delivery device and a second relaxed configuration defining a first support ring and a second support ring when removed from the elongate delivery device; said elongate member in said circular configuration shaped to have a distance between a first ring tissue engaging surface and a second ring tissue engaging surface; at least one suture coupled to said elongate member for seating said member against the treatment site; at least one detachable suture removably coupled to the elongate member; and a plurality of apertures on said first ring sufficient for attachment of sutures to the first ring.
Claim 85
Dependent Claim
152 words
A tissue connection device for use with an elongate delivery device and at least one suture on tissue at a treatment site in a patient, the device comprising: an elongate member deliverable to a target tissue site via the elongate delivery device, said elongate member assuming a first substantially linear configuration while engaged with the elongate delivery device and a second relaxed configuration defining a first support ring and a second support ring when removed from the elongate delivery device; said elongate member in said circular configuration shaped to have a distance between a first ring tissue engaging surface and a second ring tissue engaging surface; at least one suture coupled to said elongate member for seating said member against the treatment site; at least one detachable suture removably coupled to the elongate member; and a plurality of apertures on said first ring sufficient for attachment of sutures to the first ring.
Claim 86
Dependent Claim
171 words
A tissue connection device for use with an elongate delivery device and at least one suture on tissue at a treatment site in a patient, the device comprising: an elongate member deliverable to a target tissue site via the elongate delivery device, said elongate member assuming first substantially linear configuration while engaged with the elongate delivery device and a second relaxed configuration defining a first support ring and a second support ring when removed from the elongate delivery device; said elongate member in said circular configuration shaped to have a distance between a first ring tissue engaging surface and a second ring tissue engaging surface; at least one suture coupled to said elongate member for seating said member against the treatment site; at least one detachable suture removably coupled to the elongate member; and wherein said first support ring is coupled to said second ring via a wire extending radially towards the center of the two rings in a manner sufficient to pass through a non-tissue center of the targeted valve.
Claim 87
Dependent Claim
171 words
A tissue connection device for use with an elongate delivery device and at least one suture on tissue at a treatment site in a patient, the device comprising: an elongate member deliverable to a target tissue site via the elongate delivery device, said elongate member assuming first substantially linear configuration while engaged with the elongate delivery device and a second relaxed configuration defining a first support ring and a second support ring when removed from the elongate delivery device; said elongate member in said circular configuration shaped to have a distance between a first ring tissue engaging surface and a second ring tissue engaging surface; at least one suture coupled to said elongate member for seating said member against the treatment site; at least one detachable suture removably coupled to the elongate member; and wherein said first support ring is coupled to said second ring via a wire extending radially towards the center of the two rings in a manner sufficient to pass through a non-tissue center of the targeted valve.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2009-10-23 | 2010-04-24 | 2010-10-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2013-10-23 | 2014-04-24 | 2014-10-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2017-10-23 | 2018-04-24 | 2018-10-24 | $7700.00 | Window Closed / Lapsed |