Patent US3876900A successfully refreshed from Google Patents.
Patent US6699214B2 successfully refreshed from Google Patents.
US6699214B2
Expired / Lapsed
US
⏱️ 0.0 years remaining
Shear-sensitive injectable delivery system
Assignee: Boston Scientific Scimed Inc
•
Filing: 2000-01-19
•
Granted: 2004-03-02
•
Expires: 2020-01-19
Abstract
Abstract A delivery system for delivering a shear-sensitive injectable material into the body of a mammal, such as a human being, acts as a mechanical feed that continuously mixes a shear-sensitive injectable material as it delivers the shear-sensitive injectable material to a target tissue, or to a site adjacent a target tissue. In one embodiment of the invention, the delivery system comprises an injector system including a rotatable mixing member coupled to a driving system. The injector system comprises a housing defining a lumen and having an output end and a driving system connection end and includes a rotatable mixing member for coupling to the driving system and for mixing and delivering the shear-sensitive injectable material. The driving system comprises a drive mechanism, an actuator capable of actuating the drive mechanism, and an interfacing member coupled to the drive mechanism for coupling with the mixing member to rotate the mixing member when the interfacing member is driven by the drive mechanism.
Inventors
- 👤 Barry N. Gellman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 06:36
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/178; A61M5/20; A61M5/2066; A61M5/31; A61M5/315; A61M5/31596; A61M5/3129; A61M5/3137; A61M2005/3139
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
102 words
An injector system, comprising: a housing defining a lumen and having an output end and a driving system connection end, the lumen comprising a proximal portion and a distal portion and the inner diameter of the proximal portion being substantially larger than the inner diameter of the distal portion; a mixing member extending within the lumen from the driving system connection end to at least the output end, the mixing member being rotatable within the lumen in both the proximal portion and the distal portion; and a needle assembly coupled to the output end of the housing, for coupling to a needle.
Claim 2
Dependent Claim
102 words
An injector system, comprising: a housing defining a lumen and having an output end and a driving system connection end, the lumen comprising a proximal portion and a distal portion and the inner diameter of the proximal portion being substantially larger than the inner diameter of the distal portion; a mixing member extending within the lumen from the driving system connection end to at least the output end, the mixing member being rotatable within the lumen in both the proximal portion and the distal portion; and a needle assembly coupled to the output end of the housing, for coupling to a needle.
Claim 3
Dependent Claim
15 words
The injector system of claim 1 , wherein the mixing member comprises a helical element.
Claim 4
Dependent Claim
14 words
The injector system of claim 2 , wherein the helical element is an auger.
Claim 5
Dependent Claim
22 words
The injector system of claim 1 , further comprising a driver guide, the driver guide positioning the mixing member within the lumen.
Claim 6
Dependent Claim
16 words
The injector system of claim 1 , wherein the needle assembly is coupled to a needle.
Claim 7
Dependent Claim
12 words
The injector system of claim 1 , further comprising an injectable material.
Claim 8
Dependent Claim
15 words
The injector system of claim 6 , wherein the injectable comprises a shear-sensitive injectable material.
Claim 9
Dependent Claim
22 words
The injector system of claim 7 , wherein the shear-sensitive injectable material comprises a cross-linked material, a carrier, and a matrix material.
Claim 10
Dependent Claim
16 words
The injector system of claim 7 , wherein the injectable material further comprises a bioactive molecule.
Claim 11
Dependent Claim
37 words
The injector system of claim 7 , wherein the housing comprises a feeder portion and a reservoir portion, and wherein the mixing member is rotatable within the feeder portion and can move linearly within the reservoir portion.
Claim 12
Dependent Claim
29 words
The injector system of claim 1 , wherein the lumen further comprises a middle portion having an inner diameter substantially larger than the inner diameter of the proximal portion.
Claim 13
Dependent Claim
64 words
The injector system of claim 1 wherein the mixing member comprises a screw having a proximal end and a distal end, the screw being-extendable and rotatable within both the proximal portion and the distal portion of the lumen, the injector system further comprising a drive mechanism coupled to the proximal end of the screw, to rotate the screw when the drive mechanism is actuated.
Claim 14
Dependent Claim
23 words
The injector system of claim 12 , further comprising an actuator, the actuator coupled to the drive mechanism to actuate the drive mechanism.
Claim 15
Dependent Claim
23 words
The injector system of claim 12 , wherein an outer diameter of the screw decreases from the proximal end to the distal end.
Claim 16
Dependent Claim
22 words
The injector system of claim 12 , wherein a pitch of the screw increases from the proximal end to the distal end.
Claim 17
Dependent Claim
24 words
The injector system of claim 12 , wherein a radial thread height of the screw increases from the proximal end to the distal end.
References Cited (Backward Citations)
DE545878C
Cited
US346265A
Cited
US2888923A
Cited
US2825134A
Cited
US3602950A
Cited
US3732858A
Cited
US3788003A
Cited
US3779383A
Cited
US4006736A
Cited
US4074362A
Cited
US4243080A
Cited
US4202635A
Cited
US4285600A
Cited
US4542176A
Cited
DE3317536A1
Cited
FR2572677A1
Cited
US4649919A
Cited
US4803075A
Cited
US5104380A
Cited
US4929238A
Cited
US5423799A
Cited
US5089606A
Cited
US5071040A
Cited
US5259749A
Cited
US5458475A
Cited
US5724994A
Cited
US5360410A
Cited
US5658261A
Cited
US5322511A
Cited
US5383884A
Cited
WO1994015660A1
Cited
US5395326A
Cited
US5397180A
Cited
US5489266A
Cited
US5770141A
Cited
US5676545A
Cited
US5674195A
Cited
US5647851A
Cited
US5653692A
Cited
US5865798A
Cited
US5899881A
Cited
US6033105A
Cited
US5842782A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2007-03-02 | 2007-09-01 | 2008-03-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2011-03-02 | 2011-09-01 | 2012-03-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2015-03-02 | 2015-09-01 | 2016-03-02 | $7700.00 | Window Closed / Lapsed |