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US6638239B1 Expired / Lapsed US ⏱️ 0.0 years remaining

Apparatus and method for treating glaucoma

Assignee: GLAYCO Corp
•
Filing: 2000-04-14
•
Granted: 2003-10-28
•
Expires: 2020-04-14
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Abstract

Abstract Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involve bypassing diseased trabecular meshwork with the use of a seton implant. The seton implant is used to prevent a healing process known as filling in, which has a tendency to close surgically created openings in the trabecular meshwork. The surgical method and novel implant are addressed to the trabecular meshwork, which is a major site of resistance to outflow in glaucoma. In addition to bypassing the diseased trabecular meshwork at the level of the trabecular meshwork, existing outflow pathways are also used or restored. The seton implant is positioned through the trabecular meshwork so that an inlet end of the seton implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.

Inventors

  • 👤 Olav B. Bergheim
  • 👤 Morteza (Mory) Gharib

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 12:29
CPC Classifications
A; A61; A61F; A61F9/00; A61F9/007; A61F9/00781; A61F9/0008; A61F9/0017; A61K; A61K9/00; A61K9/0012; A61K9/0048; A61K9/0051; A61M; A61M27/00; A61M27/002; A61P; A61P27/00; A61P27/02; A61P27/06; A61F9/008; A61F2009/00885; A61F2009/00891; A61F2250/00; A61F2250/0058; A61F2250/0067; A61M2210/00; A61M2210/06; A61M2210/0612; Y; Y10; Y10S; Y10S623/00; Y10S623/902; Y10S623/905

Claims Analysis

Total Claims: 23
Claim 1
Independent Claim 45 words
A seton comprising: an inlet portion configured to extend through a portion of the trabecular meshwork of an eye; an outlet portion configured to extend into Schlemm's canal of said eye; and a one-way valve in at least one of the inlet and outlet portions.
Claim 2
Dependent Claim 45 words
A seton comprising: an inlet portion configured to extend through a portion of the trabecular meshwork of an eye; an outlet portion configured to extend into Schlemm's canal of said eye; and a one-way valve in at least one of the inlet and outlet portions.
Claim 3
Independent Claim 80 words
A method for delivering a seton within an eye, comprising: providing an elongate guide member, said elongate guide member being selected from the group consisting of a guide wire and a fiberoptic; advancing a distal end of said guide member through at least a portion of the trabecular meshwork of the eye; advancing said seton along said guide member toward said distal end; positioning said seton to conduct aqueous humor between the anterior chamber of the eye and Schlemm's canal.
Claim 4
Independent Claim 80 words
A method for delivering a seton within an eye, comprising: providing an elongate guide member, said elongate guide member being selected from the group consisting of a guide wire and a fiberoptic; advancing a distal end of said guide member through at least a portion of the trabecular meshwork of the eye; advancing said seton along said guide member toward said distal end; positioning said seton to conduct aqueous humor between the anterior chamber of the eye and Schlemm's canal.
Claim 5
Dependent Claim 25 words
The method of claim 2 , wherein said advancing said guide member comprises advancing said guide member from the anterior chamber into the trabecular meshwork.
Claim 6
Independent Claim 75 words
An apparatus for delivering a seton to the anterior chamber of an eye comprising: an elongate tube having a lumen, an outer surface, and a distal end; a movable, elongate guide member within said lumen, configured to permit said seton to be advanced through said tube and to be positioned in the trabecular meshwork of said eye; and an opening in said outer surface of said tube, configured to allow fluid infusion into said eye.
Claim 7
Independent Claim 75 words
An apparatus for delivering a seton to the anterior chamber of an eye comprising: an elongate tube having a lumen, an outer surface, and a distal end; a movable, elongate guide member within said lumen, configured to permit said seton to be advanced through said tube and to be positioned in the trabecular meshwork of said eye; and an opening in said outer surface of said tube, configured to allow fluid infusion into said eye.
Claim 8
Dependent Claim 70 words
A seton comprising: an inlet portion configured to extend through a portion of the trabecular meshwork of an eye; and an outlet portion configured to extend into Schlemm's canal of said eye; wherein the outlet portion has at least one protrusion configured to exert traction against an inner surface of Schlemm's canal, said protrusion extending from said seton in a direction substantially perpendicular to a long axis of Schlemm's canal.
Claim 9
Dependent Claim 70 words
A seton comprising: an inlet portion configured to extend through a portion of the trabecular meshwork of an eye; and an outlet portion configured to extend into Schlemm's canal of said eye; wherein the outlet portion has at least one protrusion configured to exert traction against an inner surface of Schlemm's canal, said protrusion extending from said seton in a direction substantially perpendicular to a long axis of Schlemm's canal.
Claim 10
Dependent Claim 14 words
The seton of claim 5 , wherein said protrusion comprises at least one barb.
Claim 11
Dependent Claim 14 words
The seton of claim 5 , wherein said protrusion comprises at least one ridge.
Claim 12
Independent Claim 114 words
A method of treating glaucoma, comprising: implanting a drainage implant in a trabecular meshwork of an eye, said implant being substantially L-shaped, said implanting comprising: providing an elongate applicator, an inflow portion of said implant mounted at a distal end of the applicator such that an outflow portion of the implant extends from said applicator at an angle relative thereto; inserting the drainage implant through an incision in the eye; and transporting the drainage implant from the incision across the anterior chamber into the trabecular meshwork such that an inflow portion of the drainage implant is positioned in the anterior chamber and an outflow portion of the drainage implant is positioned in Schlemm's canal.
Claim 13
Independent Claim 114 words
A method of treating glaucoma, comprising: implanting a drainage implant in a trabecular meshwork of an eye, said implant being substantially L-shaped, said implanting comprising: providing an elongate applicator, an inflow portion of said implant mounted at a distal end of the applicator such that an outflow portion of the implant extends from said applicator at an angle relative thereto; inserting the drainage implant through an incision in the eye; and transporting the drainage implant from the incision across the anterior chamber into the trabecular meshwork such that an inflow portion of the drainage implant is positioned in the anterior chamber and an outflow portion of the drainage implant is positioned in Schlemm's canal.
Claim 14
Dependent Claim 27 words
The method of claim 8 , comprising: positioning the outflow portion generally transversely to the inflow portion when the drainage implant is implanted in the trabecular meshwork.
Claim 15
Dependent Claim 18 words
The method of claim 8 , wherein the transporting comprises advancing the drainage implant along a guide member.
Claim 16
Dependent Claim 18 words
The method of claim 8 , wherein the transporting comprises advancing the drainage implant with a delivery applicator.
Claim 17
Independent Claim 123 words
A method of treating glaucoma, comprising: implanting a drainage implant in Schlemm's canal of an eye, said implant being substantially L-shaped, said implanting comprising; providing an elongate applicator, an inflow portion of said implant mounted at a distal end of the applicator such that an outflow portion of the implant extends from said applicator at an angle relative thereto; inserting the drainage implant through an ocular incision in the eye; transporting the drainage implant from the incision through the anterior chamber of the eye to Schlemm's canal such that an inflow portion of the drainage implant is positioned to bypass the trabecular meshwork and receive fluid from the anterior chamber and an outflow portion of the drainage implant is positioned in Schlemm's canal.
Claim 18
Independent Claim 123 words
A method of treating glaucoma, comprising: implanting a drainage implant in Schlemm's canal of an eye, said implant being substantially L-shaped, said implanting comprising; providing an elongate applicator, an inflow portion of said implant mounted at a distal end of the applicator such that an outflow portion of the implant extends from said applicator at an angle relative thereto; inserting the drainage implant through an ocular incision in the eye; transporting the drainage implant from the incision through the anterior chamber of the eye to Schlemm's canal such that an inflow portion of the drainage implant is positioned to bypass the trabecular meshwork and receive fluid from the anterior chamber and an outflow portion of the drainage implant is positioned in Schlemm's canal.
Claim 19
Dependent Claim 28 words
The method of claim 12 , further comprising positioning the outflow portion generally transversely to the inflow portion when the drainage implant is implanted in the trabecular meshwork.
Claim 20
Dependent Claim 18 words
The method of claim 12 , wherein the transporting comprises advancing the drainage implant along a guide member.
Claim 21
Dependent Claim 18 words
The method of claim 12 , wherein the transporting comprises advancing the drainage implant with a delivery applicator.
Claim 22
Independent Claim 91 words
A method of treating glaucoma, comprising: inserting an implant through an incision in the eye, said implant having a blunt outflow end; transporting the implant from the incision through the anterior chamber of the eye to Schlemm's canal; cutting an opening into Schlemm's canal; advancing the blunt outflow end through the opening; and positioning the implant such that an inflow portion of the implant is positioned to bypass the trabecular meshwork and receive fluid from the anterior chamber, and the blunt outflow end of the implant is positioned in Schlemm's canal.
Claim 23
Independent Claim 91 words
A method of treating glaucoma, comprising: inserting an implant through an incision in the eye, said implant having a blunt outflow end; transporting the implant from the incision through the anterior chamber of the eye to Schlemm's canal; cutting an opening into Schlemm's canal; advancing the blunt outflow end through the opening; and positioning the implant such that an inflow portion of the implant is positioned to bypass the trabecular meshwork and receive fluid from the anterior chamber, and the blunt outflow end of the implant is positioned in Schlemm's canal.

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2006-10-27 2007-04-28 2007-10-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2010-10-27 2011-04-28 2011-10-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2014-10-27 2015-04-28 2015-10-28 $7700.00 Window Closed / Lapsed

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