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US6549800B1 Expired / Lapsed US ⏱️ 0.0 years remaining

Methods for in vivo magnetic resonance imaging

Assignee: Johns Hopkins University
•
Filing: 2000-04-14
•
Granted: 2003-04-15
•
Expires: 2020-04-14
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Abstract

Abstract The systems and methods of the present invention provide for MRI probes adapted for insertion into a plurality of body orifices, in order to evaluate the anatomy of proximate anatomic structures, to diagnose abnormalities thereof and to treat the diagnosed abnormalities. MRI probes are described that are suitable for use in the mediastinum, in the pancreaticohepaticobiliary system, in the tracheobronchopulmonary system, in the head and neck, in the genitourinary system, the gastrointestinal system, the vascular system, and in the evaluation, diagnosis and treatment of internal fluid collections.

Inventors

  • 👤 Ergin Atalar
  • 👤 Paul A. Bottomley
  • 👤 Elias Zerhouin
  • 👤 Henry Halperin
  • 👤 Elliot McVeigh
  • 👤 Albert C. Lardo

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 12:28
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/41; A61B5/414; A61B5/415; A61B5/05; A61B5/055; A61B5/418; A61B5/43; A61B5/4375; A61B5/4381; G; G01; G01R; G01R33/00; G01R33/20; G01R33/28; G01R33/285; G01R33/32; G01R33/34; G01R33/34084; H; H01; H01Q; H01Q1/00; H01Q1/36; H01Q1/362; H01Q1/40; H01Q1/44; H01Q11/00; H01Q11/02; H01Q11/08; A61B1/00; A61B1/273; A61B1/303; A61B1/307; A61B1/31; A61B10/00; A61B10/02; A61B10/0233; A61B10/0266; A61B10/0275; A61B90/00; A61B90/36; A61B90/37; A61B2090/374; A61B5/42; G01R33/36; G01R33/3628

Claims Analysis

Total Claims: 190
Claim 1
Independent Claim 81 words
A method of performing a medical intervention, comprising: providing a MRI probe adapted for insertion into a region of anatomic interest; providing an access structure through which the MRI probe may be passed to allow said MRI probe to approach the region of anatomic interest; advancing the MRI probe through the access structure toward the region of anatomic interest; obtaining magnetic resonance imaging signals from the MRI probe; and interpreting the magnetic resonance imaging signals, thereby to guide the medical intervention.
Claim 2
Independent Claim 81 words
A method of performing a medical intervention, comprising: providing a MRI probe adapted for insertion into a region of anatomic interest; providing an access structure through which the MRI probe may be passed to allow said MRI probe to approach the region of anatomic interest; advancing the MRI probe through the access structure toward the region of anatomic interest; obtaining magnetic resonance imaging signals from the MRI probe; and interpreting the magnetic resonance imaging signals, thereby to guide the medical intervention.
Claim 3
Independent Claim 65 words
A method for evaluating mediastinal anatomy, comprising: providing a MRI probe adapted for insertion into an esophagus; inserting the MRI probe into the esophagus; and obtaining from the MRI probe signals related to anatomy of a mediastinum; wherein said MRI probe has a diameter in the range of about 0.5 to 5 French and a length in the range of about 50 to 150 centimeters.
Claim 4
Independent Claim 65 words
A method for evaluating mediastinal anatomy, comprising: providing a MRI probe adapted for insertion into an esophagus; inserting the MRI probe into the esophagus; and obtaining from the MRI probe signals related to anatomy of a mediastinum; wherein said MRI probe has a diameter in the range of about 0.5 to 5 French and a length in the range of about 50 to 150 centimeters.
Claim 5
Dependent Claim 21 words
The method of claim 2 , further comprising using the MRI probe signals to identify a vascular structure of the mediastinum.
Claim 6
Dependent Claim 21 words
The method of claim 2 , further comprising using the MRI probe signals to identify a lymph node in the mediastinum.
Claim 7
Dependent Claim 16 words
The method of claim 2 wherein said MRI probe has a diameter of about 3 French.
Claim 8
Dependent Claim 16 words
The method of claim 2 wherein said MRI probe has a length of about 75 centimeters.
Claim 9
Dependent Claim 12 words
The method of claim 2 wherein said MRI probe comprises an antenna.
Claim 10
Dependent Claim 21 words
The method of claim 7 wherein said antenna has an electrical length in the range of about 2 to 15 centimeters.
Claim 11
Dependent Claim 16 words
The method of claim 7 wherein said antenna has an electrical length of about 10 centimeters.
Claim 12
Dependent Claim 14 words
The method of claim 2 wherein said MRI probe further comprises an insulator tube.
Claim 13
Dependent Claim 21 words
The method of claim 10 wherein said insulator tube has a diameter in the range of about 3 to 14 French.
Claim 14
Dependent Claim 19 words
The method of claim 10 wherein said insulator tube has a diameter in the range of about 9 French.
Claim 15
Dependent Claim 30 words
The method of claim 2 , further comprising providing an access structure suitable for insertion into the esophagus and passing the MRI probe through the access structure into the esophagus.
Claim 16
Independent Claim 68 words
A method for evaluating mediastinal anatomy, comprising: providing a MRI probe adapted for insertion into a mediastinum; providing an access structure suitable for insertion into the mediastinum and dimensionally adapted for passing the MRI probe into the mediastinum; inserting the access structure into the mediastinum; passing the MRI probe through the access structure into the mediastinum; and obtaining signals from the MRI probe that delineate the mediastinal anatomy.
Claim 17
Independent Claim 68 words
A method for evaluating mediastinal anatomy, comprising: providing a MRI probe adapted for insertion into a mediastinum; providing an access structure suitable for insertion into the mediastinum and dimensionally adapted for passing the MRI probe into the mediastinum; inserting the access structure into the mediastinum; passing the MRI probe through the access structure into the mediastinum; and obtaining signals from the MRI probe that delineate the mediastinal anatomy.
Claim 18
Independent Claim 48 words
A method for diagnosing an abnormality of a mediastinum, comprising: providing a MRI probe adapted for insertion into the mediastinum; inserting the MRI probe into the mediastinum; obtaining from the MRI probe images of an anatomic area within the mediastinum; and evaluating the images to identify the abnormality.
Claim 19
Independent Claim 48 words
A method for diagnosing an abnormality of a mediastinum, comprising: providing a MRI probe adapted for insertion into the mediastinum; inserting the MRI probe into the mediastinum; obtaining from the MRI probe images of an anatomic area within the mediastinum; and evaluating the images to identify the abnormality.
Claim 20
Dependent Claim 44 words
The method of claim 15 , further comprising: providing an access structure dimensionally adapted for insertion into the mediastinum and further dimensionally adapted to receive the MRI probe therethrough; and inserting the MRI probe through the access structure, thereby positioning it within the mediastinum.
Claim 21
Dependent Claim 20 words
The method of claim 15 , further comprising sampling the abnormality identified from the images obtained from the MRI probe.
Claim 22
Dependent Claim 15 words
The method of claim 17 , wherein the sampling is performed using a biopsy tool.
Claim 23
Dependent Claim 36 words
The method of claim 18 , wherein the biopsy tool is inserted into the mediastinum using a second access structure, said second access structure dimensionally adapted for the passage of the biopsy tool into the mediastinum.
Claim 24
Independent Claim 87 words
A system for evaluating an anatomic area of a mediastinum, comprising: a MRI probe dimensionally adapted for positioning within the mediastinum, wherein said probe produces MRI signals representing the anatomic area of the mediastinum; an access structure dimensionally adapted for entering the mediastinum and further dimensionally adapted for passing the MRI probe therethrough to enter the mediastinum; and a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the anatomic area; and a display for displaying the images.
Claim 25
Independent Claim 87 words
A system for evaluating an anatomic area of a mediastinum, comprising: a MRI probe dimensionally adapted for positioning within the mediastinum, wherein said probe produces MRI signals representing the anatomic area of the mediastinum; an access structure dimensionally adapted for entering the mediastinum and further dimensionally adapted for passing the MRI probe therethrough to enter the mediastinum; and a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the anatomic area; and a display for displaying the images.
Claim 26
Independent Claim 51 words
A method for treating an abnormality of a mediastinum, comprising: positioning a MRI probe within the mediastinum; generating from the MRI probe signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI probe signals.
Claim 27
Independent Claim 51 words
A method for treating an abnormality of a mediastinum, comprising: positioning a MRI probe within the mediastinum; generating from the MRI probe signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI probe signals.
Claim 28
Dependent Claim 24 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for insertion into an esophagus.
Claim 29
Dependent Claim 24 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for insertion into an esophagus.
Claim 30
Dependent Claim 13 words
The MRI probe of claim 22 wherein said antenna is a loop design.
Claim 31
Dependent Claim 13 words
The MRI probe of claim 22 wherein said antenna is a loopless design.
Claim 32
Independent Claim 38 words
A method for evaluating pancreaticohepaticobiliary anatomy, comprising: providing a MRI probe dimensionally adapted for insertion into a pancreaticohepaticobiliary structure; inserting the MRI probe into the pancreaticohepaticobiliary structure; and obtaining from the MRI probe signals related to pancreaticohepaticobiliary anatomy.
Claim 33
Independent Claim 38 words
A method for evaluating pancreaticohepaticobiliary anatomy, comprising: providing a MRI probe dimensionally adapted for insertion into a pancreaticohepaticobiliary structure; inserting the MRI probe into the pancreaticohepaticobiliary structure; and obtaining from the MRI probe signals related to pancreaticohepaticobiliary anatomy.
Claim 34
Dependent Claim 32 words
The method of claim 25 , further comprising providing an access structure suitable for insertion into the pancreaticohepaticobiliary structure, and passing the MRI probe through the access structure into the pancreaticohepaticobiliary structure.
Claim 35
Dependent Claim 19 words
The method of claim 26 , wherein the access structure is adapted for insertion through a common bile duct.
Claim 36
Dependent Claim 26 words
The method of claim 27 , wherein the insertion through the common bile duct further comprises insertion through a duodenum to reach the common bile duct.
Claim 37
Dependent Claim 17 words
The method of claim 26 , wherein the access structure is adapted for insertion through a gallbladder.
Claim 38
Independent Claim 54 words
A system for evaluating pancreaticohepaticobiliary anatomy, comprising: a MRI probe dimensionally adapted for positioning within a pancreaticohepaticobiliary structure, wherein said probe produces signals representing pancreaticohepaticobiliary anatomy; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the anatomy; and a display for displaying the images.
Claim 39
Independent Claim 54 words
A system for evaluating pancreaticohepaticobiliary anatomy, comprising: a MRI probe dimensionally adapted for positioning within a pancreaticohepaticobiliary structure, wherein said probe produces signals representing pancreaticohepaticobiliary anatomy; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the anatomy; and a display for displaying the images.
Claim 40
Dependent Claim 29 words
The system of claim 30 , further comprising an access structure dimensionally adapted for insertion into a pancreaticohepaticobiliary structure and further dimensionally adapted for receiving therethrough the MRI probe.
Claim 41
Independent Claim 53 words
A method for diagnosing an abnormality of a pancreaticohepaticobiliary system, comprising: providing a MRI probe dimensionally adapted for insertion into the pancreaticohepaticobiliary system; inserting the MRI probe into the pancreaticohepaticobiliary system; obtaining from the MRI probe images of an anatomic area within the pancreaticohepaticobiliary system; and evaluating the images to identify the abnormality.
Claim 42
Independent Claim 53 words
A method for diagnosing an abnormality of a pancreaticohepaticobiliary system, comprising: providing a MRI probe dimensionally adapted for insertion into the pancreaticohepaticobiliary system; inserting the MRI probe into the pancreaticohepaticobiliary system; obtaining from the MRI probe images of an anatomic area within the pancreaticohepaticobiliary system; and evaluating the images to identify the abnormality.
Claim 43
Dependent Claim 46 words
The method of claim 32 , further comprising: providing an access structure dimensionally adapted for insertion into the pancreaticohepaticobiliary system and further dimensionally adapted to receive the MRI probe therethrough; and inserting the MRI probe through the access structure, thereby positioning it within the pancreaticohepaticobiliary system.
Claim 44
Dependent Claim 19 words
The method of claim 32 further comprising sampling the abnormality identified from the images obtained from the MRI probe.
Claim 45
Dependent Claim 15 words
The method of claim 34 , wherein the sampling is performed using a biopsy tool.
Claim 46
Dependent Claim 38 words
The method of claim 35 , wherein the biopsy tool is inserted into the pancreaticohepaticobiliary system using a second access structure, said second access structure dimensionally adapted for the passage of the biopsy tool into the pancreaticohepaticobiliary system.
Claim 47
Independent Claim 52 words
A method for treating an abnormality of a pancreaticohepaticobiliary system, comprising: positioning a MRI probe within the pancreaticohepaticobiliary system; generating from the MRI probe signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI signals.
Claim 48
Independent Claim 52 words
A method for treating an abnormality of a pancreaticohepaticobiliary system, comprising: positioning a MRI probe within the pancreaticohepaticobiliary system; generating from the MRI probe signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI signals.
Claim 49
Dependent Claim 25 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for insertion into a pancreaticohepaticobiliary structure.
Claim 50
Dependent Claim 25 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for insertion into a pancreaticohepaticobiliary structure.
Claim 51
Dependent Claim 13 words
The MRI probe of claim 38 wherein said antenna is a loop design.
Claim 52
Dependent Claim 13 words
The MRI probe of claim 38 wherein said antenna is a loopless design.
Claim 53
Independent Claim 56 words
A method for evaluating tracheobronchopulmonary anatomy, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group including the trachea, the bronchi, the bronchioles, the lung parenchyma and the intrapleural space; inserting the MRI probe into the anatomic structure; and obtaining from the MRI probe signals related to tracheobronchopulmonary anatomy.
Claim 54
Independent Claim 56 words
A method for evaluating tracheobronchopulmonary anatomy, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group including the trachea, the bronchi, the bronchioles, the lung parenchyma and the intrapleural space; inserting the MRI probe into the anatomic structure; and obtaining from the MRI probe signals related to tracheobronchopulmonary anatomy.
Claim 55
Dependent Claim 32 words
The method of claim 41 , further comprising providing an access structure suitable for insertion into the anatomic structure, and passing the MRI probe through the access structure into the anatomic structure.
Claim 56
Independent Claim 75 words
A system for evaluating tracheobronchopulmonary anatomy, comprising: a MRI probe dimensionally adapted for positioning within an anatomic structure selected from the group consisting of the trachea, the bronchi, the bronchioles, the lung parenchyma and the intrapleural space, wherein said probe produces signals representing the anatomic structure; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the anatomic structure; and a display for displaying the images.
Claim 57
Independent Claim 75 words
A system for evaluating tracheobronchopulmonary anatomy, comprising: a MRI probe dimensionally adapted for positioning within an anatomic structure selected from the group consisting of the trachea, the bronchi, the bronchioles, the lung parenchyma and the intrapleural space, wherein said probe produces signals representing the anatomic structure; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the anatomic structure; and a display for displaying the images.
Claim 58
Dependent Claim 29 words
The system of claim 43 , further comprising an access structure dimensionally adapted for insertion into the anatomic structure and further dimensionally adapted for receiving therethrough the MRI probe.
Claim 59
Independent Claim 70 words
A method for diagnosing an abnormality of a tracheobronchopulmonary system, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group consisting of the trachea, the bronchi, the bronchioles, the lung parenchyma and the intrapleural space; inserting the MRI probe into the anatomic structure; obtaining from the MRI probe images of an anatomic area within the tracheobronchopulmonary system; and evaluating eimagesto identify the abnormality.
Claim 60
Independent Claim 70 words
A method for diagnosing an abnormality of a tracheobronchopulmonary system, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group consisting of the trachea, the bronchi, the bronchioles, the lung parenchyma and the intrapleural space; inserting the MRI probe into the anatomic structure; obtaining from the MRI probe images of an anatomic area within the tracheobronchopulmonary system; and evaluating eimagesto identify the abnormality.
Claim 61
Dependent Claim 46 words
The method of claim 45 , further comprising: providing an access structure dimensionally adapted for insertion into the anatomic structure and further dimensionally adapted to receive the MRI probe therethrough; and inserting the MRI probe through the access structure, thereby positioning it within the tracheobronchopulmonary system.
Claim 62
Dependent Claim 20 words
The method of claim 45 , further comprising sampling the abnormality identified from the images obtained from the MRI probe.
Claim 63
Dependent Claim 15 words
The method of claim 47 , wherein the sampling is performed using a biopsy tool.
Claim 64
Dependent Claim 38 words
The method of claim 48 , wherein the biopsy tool is inserted into the tracheobronchopulmonary system using a second access structure, said second access structure dimensionally adapted for the passage of the biopsy tool into the PHB system.
Claim 65
Independent Claim 52 words
A method for treating an abnormality of a tracheobronchopulmonary system, comprising: positioning a MRI probe within the tracheobronchopulmonary system; generating from the MRI probe signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI signals.
Claim 66
Independent Claim 52 words
A method for treating an abnormality of a tracheobronchopulmonary system, comprising: positioning a MRI probe within the tracheobronchopulmonary system; generating from the MRI probe signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI signals.
Claim 67
Dependent Claim 43 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for insertion into an anatomic structure selected from the group including the trachea, the bronchi, the bronchioles, the lung parenchyma, and the intrapleural space.
Claim 68
Dependent Claim 43 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for insertion into an anatomic structure selected from the group including the trachea, the bronchi, the bronchioles, the lung parenchyma, and the intrapleural space.
Claim 69
Dependent Claim 13 words
The MRI probe of claim 51 wherein said antenna is a loop design.
Claim 70
Dependent Claim 13 words
The MRI probe of claim 51 wherein said antenna is a loopless design.
Claim 71
Independent Claim 80 words
A method for evaluating head and neck anatomy, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group including the mouth, the nose, the pharynx, the larynx, the ear, the Eustachian tube, the salivary gland ducts, the sinuses, the orbit, the nasolacrimal duct, the globe, the carotid artery, and the distal vasculature; inserting the MRI probe into the anatomic structure; and obtaining from the MRI probe signals related to head and neck anatomy.
Claim 72
Independent Claim 80 words
A method for evaluating head and neck anatomy, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group including the mouth, the nose, the pharynx, the larynx, the ear, the Eustachian tube, the salivary gland ducts, the sinuses, the orbit, the nasolacrimal duct, the globe, the carotid artery, and the distal vasculature; inserting the MRI probe into the anatomic structure; and obtaining from the MRI probe signals related to head and neck anatomy.
Claim 73
Dependent Claim 32 words
The method of claim 54 , further comprising providing an access structure suitable for insertion into the anatomic structure, and passing the MRI probe through the access structure into the anatomic structure.
Claim 74
Independent Claim 90 words
A system for evaluating head and neck anatomy, comprising: a MRI probe dimensionally adapted for positioning within an anatomic structure selected from the group consisting of the mouth, the nose, the pharynx, the larynx, the ear, the Eustachian tube, the salivary gland ducts, the sinuses, the orbit, the nasolacrimal duct and the globe, wherein said probe produces signals representing head and neck anatomy; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the anatomy; and display for displaying the images.
Claim 75
Independent Claim 90 words
A system for evaluating head and neck anatomy, comprising: a MRI probe dimensionally adapted for positioning within an anatomic structure selected from the group consisting of the mouth, the nose, the pharynx, the larynx, the ear, the Eustachian tube, the salivary gland ducts, the sinuses, the orbit, the nasolacrimal duct and the globe, wherein said probe produces signals representing head and neck anatomy; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the anatomy; and display for displaying the images.
Claim 76
Dependent Claim 29 words
The system of claim 56 , further comprising an access structure dimensionally adapted for insertion into the anatomic structure and further dimensionally adapted for receiving therethrough the MRI probe.
Claim 77
Independent Claim 89 words
A method for diagnosing an abnormality of the head and neck, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group consisting of the mouth, the nose, the pharynx, the larynx, the ear, the Eustachian tube, the salivary gland ducts, the sinuses, the orbit, the nasolacrimal duct and the globe; inserting the MRI probe into the anatomic structure; obtaining from the MRI probe images of an anatomic area within the head and neck area; and evaluating the images to identify the abnormality.
Claim 78
Independent Claim 89 words
A method for diagnosing an abnormality of the head and neck, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group consisting of the mouth, the nose, the pharynx, the larynx, the ear, the Eustachian tube, the salivary gland ducts, the sinuses, the orbit, the nasolacrimal duct and the globe; inserting the MRI probe into the anatomic structure; obtaining from the MRI probe images of an anatomic area within the head and neck area; and evaluating the images to identify the abnormality.
Claim 79
Dependent Claim 46 words
The method of claim 58 , further comprising: providing an access structure dimensionally adapted for insertion into the anatomic structure, and further dimensionally adapted to receive the MRI probe therethrough; and inserting the MRI probe through the access structure, thereby positioning it within the anatomic structure.
Claim 80
Dependent Claim 20 words
The method of claim 58 , further comprising sampling the abnormality identified from the images obtained from the MRI probe.
Claim 81
Dependent Claim 15 words
The method of claim 60 , wherein the sampling is performed using a biopsy tool.
Claim 82
Dependent Claim 67 words
The method of claim 61 , wherein the biopsy tool is inserted into a second anatomic structure selected from the group consisting of the mouth, the nose, the pharynx, the larynx, the ear, the Eustachian tube, the salivary gland ducts, the sinuses, the skin, the muscles, the orbit, the nasolacrimal duct and the globe in order to gain access to the abnormality of the head and neck.
Claim 83
Independent Claim 86 words
A method for treating an abnormality of the head and neck, comprising: positioning a MRI probe within an anatomic structure selected from the group consisting of the mouth, the nose, the pharynx, the larynx, the ear, the Eustachian tube, the salivary gland ducts, the sinuses, the orbit, the nasolacrimal duct and the globe; generating from the probe MRI signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI signals.
Claim 84
Independent Claim 86 words
A method for treating an abnormality of the head and neck, comprising: positioning a MRI probe within an anatomic structure selected from the group consisting of the mouth, the nose, the pharynx, the larynx, the ear, the Eustachian tube, the salivary gland ducts, the sinuses, the orbit, the nasolacrimal duct and the globe; generating from the probe MRI signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI signals.
Claim 85
Dependent Claim 56 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for insertion into an anatomic structure selected from the group including the mouth, the nose, the pharynx, the larynx, the ear, the Eustachian tube, the salivary gland ducts, the sinuses, the orbit, the nasolacrimal, and the globe.
Claim 86
Dependent Claim 56 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for insertion into an anatomic structure selected from the group including the mouth, the nose, the pharynx, the larynx, the ear, the Eustachian tube, the salivary gland ducts, the sinuses, the orbit, the nasolacrimal, and the globe.
Claim 87
Dependent Claim 13 words
The MRI probe of claim 64 wherein said antenna is a loop design.
Claim 88
Dependent Claim 13 words
The MRI probe of claim 64 wherein said antenna is a loopless design.
Claim 89
Independent Claim 70 words
A method for evaluating genitourinary anatomy, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group consisting of the urethra, the ureter, the bladder, the renal pelvis, the anus, the vagina, the cervix, the fallopian tube, the pouch of Douglas and space of Retzius; inserting the MRI probe into the anatomic structure; and obtaining from the MRI probe signals related to genitourinary anatomy.
Claim 90
Independent Claim 70 words
A method for evaluating genitourinary anatomy, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group consisting of the urethra, the ureter, the bladder, the renal pelvis, the anus, the vagina, the cervix, the fallopian tube, the pouch of Douglas and space of Retzius; inserting the MRI probe into the anatomic structure; and obtaining from the MRI probe signals related to genitourinary anatomy.
Claim 91
Dependent Claim 22 words
The method of claim 67 , wherein said MRI probe has a diameter in the range of about 0.5 to 55 French.
Claim 92
Dependent Claim 22 words
The method of claim 67 , wherein said MRI probe has a diameter in the range of about 0.5 to 9 French.
Claim 93
Dependent Claim 22 words
The method of claim 67 , wherein said MRI probe has a diameter in the range of about 0.5 to 3 French.
Claim 94
Dependent Claim 17 words
The method of claim 67 , wherein said MRI probe has a diameter of about 3 French.
Claim 95
Dependent Claim 17 words
The method of claim 67 , wherein said MRI probe has a diameter of about 4 French.
Claim 96
Dependent Claim 17 words
The method of claim 67 , wherein said MRI probe has a diameter of about 9 French.
Claim 97
Dependent Claim 21 words
The method of claim 67 wherein said MRI probe has a length in the range of about 5 to 150 centimeters.
Claim 98
Dependent Claim 21 words
The method of claim 67 wherein said MRI probe has a length in the range of about 20 to 70 centimeters.
Claim 99
Dependent Claim 21 words
The method of claim 67 wherein said MRI probe has a length in the range of about 30 to 35 centimeters.
Claim 100
Dependent Claim 11 words
The method of claim 67 wherein said probe is “C” shaped.
Claim 101
Dependent Claim 12 words
The method of claim 67 wherein said MRI probe comprises an antenna.
Claim 102
Dependent Claim 20 words
The method of claim 78 wherein said antenna has a length in the range of about 1 to 30 centimeters.
Claim 103
Dependent Claim 17 words
The method of claim 78 wherein said antenna has a length of about 2 to 20 centimeters.
Claim 104
Dependent Claim 15 words
The method of claim 78 wherein said antenna has a length of about 7 centimeters.
Claim 105
Dependent Claim 15 words
The method of claim 78 wherein said antenna has a length of about 10 centimeters.
Claim 106
Dependent Claim 15 words
The method of claim 78 wherein said antenna has a length of about 20 centimeters.
Claim 107
Dependent Claim 14 words
The method of claim 67 wherein said MRI probe further comprises an insulator tube.
Claim 108
Dependent Claim 21 words
The method of claim 84 wherein said insulator tube has a diameter in the range of about 2 to 60 French.
Claim 109
Dependent Claim 21 words
The method of claim 84 wherein said insulator tube has a diameter in the range of about 9 to 15 French.
Claim 110
Dependent Claim 32 words
The method of claim 67 , further comprising providing an access structure suitable for insertion into the anatomic structure, and passing the MRI probe through the access structure into the anatomic structure.
Claim 111
Independent Claim 87 words
A system for evaluating genitourinary anatomy, comprising: a MRI probe dimensionally adapted for positioning within an anatomic structure selected from the group consisting of the urethra, the ureter, the bladder, the renal pelvis, the anus, the vagina, the cervix, the fallopian tube and the pouch of Douglas and space of Retzius, wherein said probe produces signals representing genitourinary anatomy; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the anatomy; and a display for displayng the images.
Claim 112
Independent Claim 87 words
A system for evaluating genitourinary anatomy, comprising: a MRI probe dimensionally adapted for positioning within an anatomic structure selected from the group consisting of the urethra, the ureter, the bladder, the renal pelvis, the anus, the vagina, the cervix, the fallopian tube and the pouch of Douglas and space of Retzius, wherein said probe produces signals representing genitourinary anatomy; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the anatomy; and a display for displayng the images.
Claim 113
Dependent Claim 29 words
The system of claim 88 , further comprising an access structure dimensionally adapted for insertion into the anatomic structure and further dimensionally adapted for receiving therethrough the MRI probe.
Claim 114
Independent Claim 83 words
A method for diagnosing a genitourinary abnormality, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group consisting of the urethra, the ureter, the bladder, the renal pelvis, the anus, the vagina, the cervix, the fallopian tube and the pouch of Douglas and space of Retzius; inserting the MRI probe into the anatomic structure; obtaining from the MRI probe images of an anatomic area within the genitourinary area; and evaluating the images to identify the abnormality.
Claim 115
Independent Claim 83 words
A method for diagnosing a genitourinary abnormality, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group consisting of the urethra, the ureter, the bladder, the renal pelvis, the anus, the vagina, the cervix, the fallopian tube and the pouch of Douglas and space of Retzius; inserting the MRI probe into the anatomic structure; obtaining from the MRI probe images of an anatomic area within the genitourinary area; and evaluating the images to identify the abnormality.
Claim 116
Dependent Claim 46 words
The method of claim 90 , further comprising: providing an access structure dimensionally adapted for insertion into the anatomic structure, and further dimensionally adapted to receive the MRI probe therethrough; and inserting the MRI probe through the access structure, thereby positioning it within the anatomic structure.
Claim 117
Dependent Claim 20 words
The method of claim 90 , further comprising sampling the abnormality identified from the images obtained from the MRI probe.
Claim 118
Dependent Claim 15 words
The method of claim 92 , wherein the sampling is performed using a biopsy tool.
Claim 119
Dependent Claim 62 words
The method of claim 93 , wherein the biopsy tool is inserted into a second anatomic structure selected from the group consisting of the of the urethra, the ureter, the bladder, the renal pelvis, the anus, the vagina, the cervix, the fallopian tube, the peritoneal cavity, the pouch of Douglas and space of Retzius in order to gain access to the abnormality.
Claim 120
Independent Claim 82 words
A method for treating a genitourinary abnormality, comprising: positioning a MRI probe within an anatomic structure selected from the group consisting of the urethra, the ureter, the bladder, the renal pelvis, the anus, the vagina, the cervix, the fallopian tube and the pouch of Douglas and space of Retzius; generating from the probe MRI signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI signals.
Claim 121
Independent Claim 82 words
A method for treating a genitourinary abnormality, comprising: positioning a MRI probe within an anatomic structure selected from the group consisting of the urethra, the ureter, the bladder, the renal pelvis, the anus, the vagina, the cervix, the fallopian tube and the pouch of Douglas and space of Retzius; generating from the probe MRI signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI signals.
Claim 122
Dependent Claim 57 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for insertion into an anatomic structure selected from the group including the urethra, the ureter, the bladder, the renal pelvis, the anus, the vagina, the cervix, the fallopian tube, the Pouch of Douglas, and the space of Retzius.
Claim 123
Dependent Claim 57 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for insertion into an anatomic structure selected from the group including the urethra, the ureter, the bladder, the renal pelvis, the anus, the vagina, the cervix, the fallopian tube, the Pouch of Douglas, and the space of Retzius.
Claim 124
Dependent Claim 13 words
The MRI probe of claim 96 wherein said antenna is a loop design.
Claim 125
Dependent Claim 10 words
The MRI probe of claim 96 is a loopless design.
Claim 126
Independent Claim 47 words
A method for diagnosing an internal fluid collection, comprising: providing a MRI probe dimensionally adapted for insertion into the internal fluid collection; inserting the MRI probe into the internal fluid collection; and obtaining from the MRI probe signals related to anatomic structures surrounding the internal fluid collection.
Claim 127
Independent Claim 47 words
A method for diagnosing an internal fluid collection, comprising: providing a MRI probe dimensionally adapted for insertion into the internal fluid collection; inserting the MRI probe into the internal fluid collection; and obtaining from the MRI probe signals related to anatomic structures surrounding the internal fluid collection.
Claim 128
Dependent Claim 20 words
The method of claim 99 , wherein the internal fluid collection comprises a cyst, a pseudocyst or a pus collection.
Claim 129
Dependent Claim 34 words
The method of claim 99 , further comprising providing an access structure suitable for insertion into the internal fluid collection, and passing the MRI probe through the access structure into the internal fluid collection.
Claim 130
Dependent Claim 19 words
The method of claim 101 , further comprising removing contents of the internal fluid collection through the access structure.
Claim 131
Dependent Claim 20 words
The method of claim 101 , further comprising injecting an agent into the internal fluid collection through the access structure.
Claim 132
Independent Claim 61 words
A method for evaluating gastrointestinal anatomy, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group consisting of the esophagus, the stomach, the duodenum, the jejunum, the ileum, the appendix, the colon and the rectum; inserting the MRI probe into the anatomic structure; and obtaining from the MRI probe signals related to gastrointestinal anatomy.
Claim 133
Independent Claim 61 words
A method for evaluating gastrointestinal anatomy, comprising: providing a MRI probe dimensionally adapted for insertion into an anatomic structure selected from the group consisting of the esophagus, the stomach, the duodenum, the jejunum, the ileum, the appendix, the colon and the rectum; inserting the MRI probe into the anatomic structure; and obtaining from the MRI probe signals related to gastrointestinal anatomy.
Claim 134
Dependent Claim 21 words
The method of claim 104 wherein said MRI probe has a length in the range of about 50 to 300 centimeters.
Claim 135
Dependent Claim 19 words
The method of claim 104 wherein said MRI probe has a length about equal to that of an endoscope.
Claim 136
Dependent Claim 21 words
The method of claim 104 wherein said MRI probe has a length in the range of about 100 to 150 centimeters.
Claim 137
Dependent Claim 16 words
The method of claim 104 wherein said MRI probe has a length of about 100 centimeters.
Claim 138
Dependent Claim 16 words
The method of claim 104 wherein said MRI probe has a length of about 150 centimeters.
Claim 139
Dependent Claim 12 words
The method of claim 104 wherein said MRI probe comprises an antenna.
Claim 140
Dependent Claim 20 words
The method of claim 110 wherein said antenna has a length in the range of about 1 to 30 centimeters.
Claim 141
Dependent Claim 17 words
The method of claim 110 wherein said antenna has a length of about 2 to 10 centimeters.
Claim 142
Dependent Claim 14 words
The method of claim 104 wherein said MRI probe further comprises an insulator tube.
Claim 143
Dependent Claim 21 words
The method of claim 113 wherein said insulator tube has a diameter in the range of about 1 to 2.5 French.
Claim 144
Dependent Claim 22 words
The method of claim 113 , wherein said insulator tube has a diameter in the range of about 10 to 20 French.
Claim 145
Dependent Claim 22 words
The method of claim 113 , wherein said insulator tube has a diameter in the range of about 15 to 17 French.
Claim 146
Dependent Claim 17 words
The method of claim 113 , wherein said insulator tube has a diameter of about ⅓ Inch.
Claim 147
Dependent Claim 32 words
The method of claim 104 , further comprising providing an access structure suitable for insertion into the anatomic structure, and passing the MRI probe through the access structure into the anatomic structure.
Claim 148
Independent Claim 77 words
A system for evaluating gastrointestinal anatomy, comprising: a MRI probe dimensionally adapted for positioning within an anatomic structure selected from the group consisting of the esophagus, the stomach, the duodenum, the jejunum, the ileum, the appendix, the colon and the rectum, wherein said probe produces signals representing gastrointestinal anatomy; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to gastrointestinal anatomy; and a display for displaying the images.
Claim 149
Independent Claim 77 words
A system for evaluating gastrointestinal anatomy, comprising: a MRI probe dimensionally adapted for positioning within an anatomic structure selected from the group consisting of the esophagus, the stomach, the duodenum, the jejunum, the ileum, the appendix, the colon and the rectum, wherein said probe produces signals representing gastrointestinal anatomy; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to gastrointestinal anatomy; and a display for displaying the images.
Claim 150
Independent Claim 48 words
A method for diagnosing an abnormality of gastrointestinal anatomy, comprising: providing a MRI probe dimensionally adapted for insertion into a gastrointestinal system; inserting the MRI probe into the gastrointestinal system; obtaining from the MRI probe images of the gastrointestinal anatomy; and evaluating the images to identify the abnormality.
Claim 151
Independent Claim 48 words
A method for diagnosing an abnormality of gastrointestinal anatomy, comprising: providing a MRI probe dimensionally adapted for insertion into a gastrointestinal system; inserting the MRI probe into the gastrointestinal system; obtaining from the MRI probe images of the gastrointestinal anatomy; and evaluating the images to identify the abnormality.
Claim 152
Dependent Claim 46 words
The method of claim 120 , further comprising: providing an access structure dimensionally adapted for insertion into the gastrointestinal system and further dimensionally adapted to receive the MRI probe therethrough; and inserting the MRI probe through the access structure, thereby positioning it within the gastrointestinal system.
Claim 153
Dependent Claim 20 words
The method of claim 120 , further comprising sampling the abnormality identified from the images obtained from the MRI probe.
Claim 154
Dependent Claim 15 words
The method of claim 122 , wherein the sampling is performed using a biopsy tool.
Claim 155
Dependent Claim 38 words
The method of claim 123 , wherein the biopsy tool is inserted into the gastrointestinal system using a second access structure, said second access structure dimensionally adapted for the passage of the biopsy tool into the gastrointestinal system.
Claim 156
Independent Claim 51 words
A method for treating an abnormality of gastrointestinal anatomy, comprising: positioning a MRI probe within a gastrointestinal system; generating from the MRI probe signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI signals.
Claim 157
Independent Claim 51 words
A method for treating an abnormality of gastrointestinal anatomy, comprising: positioning a MRI probe within a gastrointestinal system; generating from the MRI probe signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI signals.
Claim 158
Dependent Claim 25 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for insertion into a gastrointestinal system.
Claim 159
Dependent Claim 25 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for insertion into a gastrointestinal system.
Claim 160
Dependent Claim 13 words
The MRI probe of claim 126 wherein said antenna is a loop design.
Claim 161
Dependent Claim 13 words
The MRI probe of claim 126 wherein said antenna is a loopless design.
Claim 162
Independent Claim 43 words
A method for evaluating anatomy of a vascular system, comprising: providing a MRI probe adapted for insertion into the vascular system; inserting the MRI probe into the vascular system; and obtaining from the MRI probe signals related to anatomy of the vascular system.
Claim 163
Independent Claim 43 words
A method for evaluating anatomy of a vascular system, comprising: providing a MRI probe adapted for insertion into the vascular system; inserting the MRI probe into the vascular system; and obtaining from the MRI probe signals related to anatomy of the vascular system.
Claim 164
Dependent Claim 29 words
The method of claim 129 , further comprising providing an access structure suitable for intravascular insertion and passing the MRI probe through the access structure into the vascular system.
Claim 165
Independent Claim 79 words
A method for evaluating anatomy of a vascular system, comprising: providing a MRI probe adapted for insertion into the vascular system; providing an access structure suitable for insertion into the vascular system and dimensionally adapted for passing the MRI probe into the vascular system; inserting the access structure into the vascular system; passing the MRI probe through the access structure into the vascular system; and obtaining signals from the MRI probe that delineate the anatomy of the vascular system.
Claim 166
Independent Claim 79 words
A method for evaluating anatomy of a vascular system, comprising: providing a MRI probe adapted for insertion into the vascular system; providing an access structure suitable for insertion into the vascular system and dimensionally adapted for passing the MRI probe into the vascular system; inserting the access structure into the vascular system; passing the MRI probe through the access structure into the vascular system; and obtaining signals from the MRI probe that delineate the anatomy of the vascular system.
Claim 167
Independent Claim 48 words
A method for diagnosing an abnormality of the vascular system, comprising: providing a MRI probe adapted for intravascular insertion; inserting the MRI probe into the vascular system; obtaining from the MRI probe images of an area of the vascular system; and diagnosing the abnormality by interpreting the images.
Claim 168
Independent Claim 48 words
A method for diagnosing an abnormality of the vascular system, comprising: providing a MRI probe adapted for intravascular insertion; inserting the MRI probe into the vascular system; obtaining from the MRI probe images of an area of the vascular system; and diagnosing the abnormality by interpreting the images.
Claim 169
Dependent Claim 43 words
The method of claim 132 , further comprising: providing an access structure dimensionally adapted for intravascular insertion and further dimensionally adapted to receive the MRI probe therethrough; and inserting the MRI probe through the access structure, thereby positioning it within the vascular system.
Claim 170
Dependent Claim 20 words
The method of claim 132 , further comprising sampling the abnormality identified from the images obtained from the MRI probe.
Claim 171
Dependent Claim 15 words
The method of claim 134 , wherein the sampling is performed using a biopsy tool.
Claim 172
Dependent Claim 38 words
The method of claim 135 , wherein the biopsy tool is inserted into the vascular system using a second access structure, said second access structure dimensionally adapted for the passage of the biopsy tool into the vascular system.
Claim 173
Independent Claim 91 words
A system for evaluating an anatomic area of the vascular system, comprising: a MRI probe dimensionally adapted for positioning within the vascular system, wherein said probe produces MRI signals representing an anatomic area of the vascular system; an access structure dimensionally adapted for entering the vascular system and further dimensionally adapted for passing the MRI probe therethrough to enter the vascular system; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the anatomic area; and a display for displaying the images.
Claim 174
Independent Claim 91 words
A system for evaluating an anatomic area of the vascular system, comprising: a MRI probe dimensionally adapted for positioning within the vascular system, wherein said probe produces MRI signals representing an anatomic area of the vascular system; an access structure dimensionally adapted for entering the vascular system and further dimensionally adapted for passing the MRI probe therethrough to enter the vascular system; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the anatomic area; and a display for displaying the images.
Claim 175
Independent Claim 53 words
A method for treating an abnormality of the vascular system, comprising: positioning a MRI probe within the vascular system; generating from the MRI probe signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI probe signals.
Claim 176
Independent Claim 53 words
A method for treating an abnormality of the vascular system, comprising: positioning a MRI probe within the vascular system; generating from the MRI probe signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI probe signals.
Claim 177
Dependent Claim 22 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for intravascular insertion.
Claim 178
Dependent Claim 22 words
An MRI probe, comprising: an antenna; and a probe shaft; wherein said antenna and said probe shaft are adapted for intravascular insertion.
Claim 179
Dependent Claim 13 words
The MRI probe of claim 139 wherein said antenna is a loop design.
Claim 180
Dependent Claim 13 words
The MRI probe of claim 139 wherein said antenna is a loopless design.
Claim 181
Independent Claim 83 words
A system for evaluating a perivascular structure, comprising: a MRI probe dimensionally adapted for positioning within a vascular system, wherein said probe produces MRI signals representing the perivascular structure; an access structure dimensionally adapted for entering the vascular system and further dimensionally adapted for passing the MRI probe therethrough to enter the vascular system; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the perivascular structure; and a display for displaying the images.
Claim 182
Independent Claim 83 words
A system for evaluating a perivascular structure, comprising: a MRI probe dimensionally adapted for positioning within a vascular system, wherein said probe produces MRI signals representing the perivascular structure; an access structure dimensionally adapted for entering the vascular system and further dimensionally adapted for passing the MRI probe therethrough to enter the vascular system; a signal processor that receives signals produced by the MRI probe and generates from the signals images related to the perivascular structure; and a display for displaying the images.
Claim 183
Independent Claim 57 words
A method for diagnosing an abnormality of a perivascular structure, comprising: providing a MRI probe adapted for intravascular insertion; positioning a MRI probe within a vascular system; directing the MRI probe through the vascular system towards the perivascular structure; obtaining from the MRI probe images of the perivascular structure; and evaluating the images to identify the abnormality.
Claim 184
Independent Claim 57 words
A method for diagnosing an abnormality of a perivascular structure, comprising: providing a MRI probe adapted for intravascular insertion; positioning a MRI probe within a vascular system; directing the MRI probe through the vascular system towards the perivascular structure; obtaining from the MRI probe images of the perivascular structure; and evaluating the images to identify the abnormality.
Claim 185
Dependent Claim 20 words
The method of claim 143 , further comprising sampling the abnormality identified from the images obtained from the MRI probe.
Claim 186
Dependent Claim 15 words
The method of claim 144 , wherein the sampling is performed using a biopsy tool.
Claim 187
Independent Claim 65 words
A method for treating an abnormality of a perivascular structure, comprising: positioning a MRI probe within a vascular system; directing the MRI probe through the vascular system towards the perivascular structure; generating from the MRI probe signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI probe signals.
Claim 188
Independent Claim 65 words
A method for treating an abnormality of a perivascular structure, comprising: positioning a MRI probe within a vascular system; directing the MRI probe through the vascular system towards the perivascular structure; generating from the MRI probe signals that produce an image of the abnormality; and directing a therapeutic intervention towards the abnormality guided by the image of the abnormality produced from the MRI probe signals.
Claim 189
Dependent Claim 22 words
The method of claim 146 , wherein access to the abnormality for performing the therapeutic intervention is provided by an extravascular route.
Claim 190
Dependent Claim 22 words
The method of claim 146 , wherein access to the abnormality for performing the therapeutic intervention is provided by an intravascular route.

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