US6494898B1
Expired / Lapsed
US
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Absorbable copolymers and surgical articles fabricated therefrom
Assignee: United States Surgical Corp
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Filing: 1998-09-26
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Granted: 2002-12-17
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Expires: 2018-09-26
Abstract
Abstract A synthetic absorbable monofilament comprising glycolide and epsilon caprolactone is provided. The monofilament exhibits physical characteristics equivalent to or superior than gut sutures. The monofilaments can be fabricated into a wide variety of surgical devices such as sutures, meshes, and the like.
Inventors
- 👤 Mark S. Roby
- 👤 Ying Jiang
- 👤 Lyudmila K. Kokish
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:33
CPC Classifications
A; A61; A61L; A61L17/00; A61L17/06; A61L17/10; A61L17/12
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
74 words
A suture fabricated from a random copolymer comprising from about 68 to about 75 weight percent glycolide and about 25 to about 32 weight percent epsilon-caprolactone, the suture exhibiting two week strength retention, mass loss of about 50% in 32 hours as measured in Sorenson's buffer solution at 80° C. and a modulus ranging from about 150 kpsi to about 250 kpsi and an knot pull strength of about 1.7 to about 2.8 kg.
Claim 2
Dependent Claim
74 words
A suture fabricated from a random copolymer comprising from about 68 to about 75 weight percent glycolide and about 25 to about 32 weight percent epsilon-caprolactone, the suture exhibiting two week strength retention, mass loss of about 50% in 32 hours as measured in Sorenson's buffer solution at 80° C. and a modulus ranging from about 150 kpsi to about 250 kpsi and an knot pull strength of about 1.7 to about 2.8 kg.
Claim 3
Dependent Claim
24 words
The suture of claim 1 wherein the suture wherein the random copolymer comprises about 30 weight percent glycolide and about 70 weight percent glycolide.
Claim 4
Dependent Claim
20 words
The suture of claim 1 wherein the suture is a size 3/0 suture and the modulus is about 170 kpsi.
Claim 5
Dependent Claim
22 words
The suture of claim 1 wherein the suture is a size 3/0 suture and the knot pull strength is about 2.6 kg.
Claim 6
Dependent Claim
21 words
The suture of claim 1 wherein the suture is a size 3/0 suture and the tensile strength is about 102 kpsi.
Claim 7
Dependent Claim
33 words
The suture of claim 1 wherein the suture is a size 3/0 suture and exhibits the following characteristics: modulus about 170 kpsi knot pull strength about 2.6 kg tensile strength about 102 kpsi.
Claim 8
Dependent Claim
10 words
The suture of claim 1 comprising a medico-surgically useful substance.
Claim 9
Dependent Claim
31 words
The suture of claim 1 wherein the random copolymer possesses an inherent viscosity of about 1.0 to about 1.8 dl/g at 30° C. and a concentration of 0.25 g/dl in HFIP.
Claim 10
Dependent Claim
31 words
The suture of claim 1 wherein the suture is a size 3/0 suture and exhibits a mass loss of about 50% after 32 hours in Sorenson's buffer solution at 80° C.
Claim 11
Dependent Claim
31 words
The suture of claim 1 wherein the suture is a size 3/0 suture and exhibits a mass loss of about 30% after 72 hours in Sorenson's buffer solution at 80° C.
Claim 12
Dependent Claim
31 words
The suture of claim 1 wherein the suture is a size 3/0 suture and exhibits a mass loss of about 12% after 120 hours in Sorenson's buffer solution at 80° C.
Claim 13
Independent Claim
88 words
A method of suturing a wound comprising: a. providing a suture fabricated from a random copolymer about 68 to about 75 weight percent glycolido and about 25 to about 32 weight percent epsilon-caprolactone, the suture exhibiting two week strength retention, mass loss of about 50% in 32 hours as measured in Sorenson's buffer solution at and a modulus ranging from about 150 to about 250 and an knot pull strength of about 1.7 to about 2.88; and b. passing said needled suture through tissue to create wound closure.
Claim 14
Independent Claim
88 words
A method of suturing a wound comprising: a. providing a suture fabricated from a random copolymer about 68 to about 75 weight percent glycolido and about 25 to about 32 weight percent epsilon-caprolactone, the suture exhibiting two week strength retention, mass loss of about 50% in 32 hours as measured in Sorenson's buffer solution at and a modulus ranging from about 150 to about 250 and an knot pull strength of about 1.7 to about 2.88; and b. passing said needled suture through tissue to create wound closure.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2005-12-16 | 2006-06-17 | 2006-12-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2009-12-16 | 2010-06-17 | 2010-12-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2013-12-16 | 2014-06-17 | 2014-12-17 | $7700.00 | Window Closed / Lapsed |