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US6074338A Expired / Lapsed US ⏱️ 0.0 years remaining

Medical appliances for the treatment of blood vessels by means of ionizing radiation

Assignee: Schneider Europe GmbH
•
Filing: 1994-06-28
•
Granted: 2000-06-13
•
Expires: 2014-06-28
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Abstract

Abstract A catheter with a balloon mounted coaxially thereon, and a radiation emitting source disposed and essentially centered in the catheter distal portion.

Inventors

  • 👤 Youri Popowski
  • 👤 Vitali Verin

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 14:47
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/10; A61N5/1001; A61N5/1002; A61M; A61M25/00; A61M25/10; A61M2025/1043; A61M2025/1047; A61N2005/1003

Claims Analysis

Total Claims: 53
Claim 1
Independent Claim 77 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) a beta radiation emitting source comprising 90 Yttrium disposed within the catheter distal portion; and (c) a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the beta radiation emitting source in the coronary blood vessel.
Claim 2
Dependent Claim 77 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) a beta radiation emitting source comprising 90 Yttrium disposed within the catheter distal portion; and (c) a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the beta radiation emitting source in the coronary blood vessel.
Claim 3
Dependent Claim 15 words
The medical device of claim 1, wherein the beta radiation emitting source comprises a filament.
Claim 4
Dependent Claim 18 words
The medical device of claim 2, wherein the filament diameter is less than or equal to 0.9 mm.
Claim 5
Dependent Claim 15 words
The medical device of claim 3, wherein the filament diameter is less than 0.2 mm.
Claim 6
Dependent Claim 15 words
The medical device of claim 2, wherein the filament is axially moveable within the catheter.
Claim 7
Dependent Claim 19 words
The medical device of claim 5, wherein the filament is adapted for insertion into and withdrawal from the catheter.
Claim 8
Dependent Claim 24 words
The medical device of claim 2, further comprising a guide wire slidably disposed within the catheter, wherein the filament is affixed to the guidewire.
Claim 9
Dependent Claim 15 words
The medical device of claim 2, wherein the filament is affixed to a titanium wire.
Claim 10
Dependent Claim 19 words
The medical device of claim 1, wherein the beta radiation emitting source is essentially axially centered within the balloon.
Claim 11
Dependent Claim 20 words
The medical device of claim 1, wherein the balloon is substantially cylindrical upon expansion and annularly affixed to the catheter.
Claim 12
Dependent Claim 18 words
The medical device of claim 10, wherein the balloon is adapted to perform a percutaneous transluminal angioplasty procedure.
Claim 13
Dependent Claim 94 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) a radiation emitting source disposed within the catheter distal portion, the radiation emitting source comprising 90 Yttrium adapted to irradiate a blood vessel wall without substantially irradiating tissue beyond the blood vessel wall; and (c) a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially center the radiation emitting source in the coronary blood vessel.
Claim 14
Dependent Claim 94 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) a radiation emitting source disposed within the catheter distal portion, the radiation emitting source comprising 90 Yttrium adapted to irradiate a blood vessel wall without substantially irradiating tissue beyond the blood vessel wall; and (c) a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially center the radiation emitting source in the coronary blood vessel.
Claim 15
Dependent Claim 14 words
The medical device of claim 12, wherein the radiation emitting source comprises a filament.
Claim 16
Dependent Claim 18 words
The medical device of claim 13, wherein the filament diameter is less than or equal to 0.9 mm.
Claim 17
Dependent Claim 15 words
The medical device of claim 14, wherein the filament diameter is less than 0.2 mm.
Claim 18
Dependent Claim 24 words
The medical device of claim 13, further comprising a guide wire slidably disposed within the catheter, wherein the filament is affixed to the guidewire.
Claim 19
Dependent Claim 15 words
The medical device of claim 13, wherein the filament is affixed to a titanium wire.
Claim 20
Dependent Claim 18 words
The medical device of claim 12, wherein the radiation emitting source is essentially axially centered within the balloon.
Claim 21
Dependent Claim 15 words
The medical device of claim 13, wherein the filament is axially moveable within the catheter.
Claim 22
Dependent Claim 19 words
The medical device of claim 19, wherein the filament is adapted for insertion into and withdrawal from the catheter.
Claim 23
Dependent Claim 20 words
The medical device of claim 12, wherein the balloon is substantially cylindrical upon expansion and annularly affixed to the catheter.
Claim 24
Dependent Claim 18 words
The medical device of claim 21, wherein the balloon is adapted to perform a percutaneous transluminal angioplasty procedure.
Claim 25
Dependent Claim 18 words
The medical device of claim 12, wherein the radiation emitting filament is essentially axially centered within the balloon.
Claim 26
Dependent Claim 83 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) a radiation emitting filament comprising 90 Yttrium disposed within the catheter distal portion and having a diameter less than 0.2 mm; and (c) a balloon surrounding at least part of the catheter distal portion, and adapted to radially expand and essentially radially center the radiation emitting filament in the coronary blood vessel.
Claim 27
Dependent Claim 83 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) a radiation emitting filament comprising 90 Yttrium disposed within the catheter distal portion and having a diameter less than 0.2 mm; and (c) a balloon surrounding at least part of the catheter distal portion, and adapted to radially expand and essentially radially center the radiation emitting filament in the coronary blood vessel.
Claim 28
Dependent Claim 15 words
The medical device of claim 24, wherein the filament is axially moveable within the catheter.
Claim 29
Dependent Claim 19 words
The medical device of claim 25, wherein the filament is adapted for insertion into and withdrawal from the catheter.
Claim 30
Dependent Claim 24 words
The medical device of claim 24, further comprising a guide wire slidably disposed within the catheter, wherein the filament is affixed to the guidewire.
Claim 31
Dependent Claim 15 words
The medical device of claim 24, wherein the filament is affixed to a titanium wire.
Claim 32
Dependent Claim 20 words
The medical device of claim 24, wherein the balloon is substantially cylindrical upon expansion and annularly affixed to the catheter.
Claim 33
Dependent Claim 18 words
The medical device of claim 29, wherein the balloon is adapted to perform a percutaneous transluminal angioplasty procedure.
Claim 34
Dependent Claim 69 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) 90 Yttrium disposed within the catheter distal portion; and (c) a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the 90 Yttrium in the coronary blood vessel.
Claim 35
Dependent Claim 69 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) 90 Yttrium disposed within the catheter distal portion; and (c) a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the 90 Yttrium in the coronary blood vessel.
Claim 36
Dependent Claim 16 words
The medical device of claim 31, where in the 90 Yttrium is comprised in a filament.
Claim 37
Dependent Claim 15 words
The medical device of claim 32, wherein the filament is axially moveable within the catheter.
Claim 38
Dependent Claim 19 words
The medical device of claim 33, wherein the filament is adapted for insertion into and withdrawal from the catheter.
Claim 39
Dependent Claim 18 words
The medical device of claim 32, wherein the filament diameter is less than or equal to 0.9 mm.
Claim 40
Dependent Claim 15 words
The medical device of claim 35, wherein the filament diameter is less than 0.2 mm.
Claim 41
Dependent Claim 24 words
The medical device of claim 32, further comprising a guide wire slidably disposed within the catheter, wherein the filament is affixed to the guidewire.
Claim 42
Dependent Claim 15 words
The medical device of claim 32, wherein the filament is affixed to a titanium wire.
Claim 43
Dependent Claim 17 words
The medical device of claim 31, wherein the 90 Yttrium is essentially axially centered within the balloon.
Claim 44
Dependent Claim 20 words
The medical device of claim 31, wherein the balloon is substantially cylindrical upon expansion and annularly affixed to the catheter.
Claim 45
Dependent Claim 18 words
The medical device of claim 40, wherein the balloon is adapted to perform a percutaneous transluminal angioplasty procedure.
Claim 46
Independent Claim 125 words
A method of preventing restenosis in a blood vessel comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; a beta radiation emitting source comprising 90 Yttrium disposed within the catheter distal portion; and a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the beta radiation emitting source in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the beta radiation emitting source essentially radially centered within a blood vessel; and (c) irradiating the treatment site with radiation including beta radiation and devoid of gamma radiation.
Claim 47
Independent Claim 125 words
A method of preventing restenosis in a blood vessel comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; a beta radiation emitting source comprising 90 Yttrium disposed within the catheter distal portion; and a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the beta radiation emitting source in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the beta radiation emitting source essentially radially centered within a blood vessel; and (c) irradiating the treatment site with radiation including beta radiation and devoid of gamma radiation.
Claim 48
Independent Claim 146 words
A method of preventing restenosis in a blood vessel comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; a radiation emitting source disposed within the catheter distal portion, the radiation emitting source comprising 90 Yttrium adapted to irradiate a blood vessel wall without substantially irradiating tissue beyond the blood vessel wall; and a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially center the radiation emitting source in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the radiation emitting source essentially radially centered within a blood vessel formed of a blood vessel wall; and (c) irradiating the blood wall without substantially irradiating tissue beyond the blood vessel wall.
Claim 49
Independent Claim 146 words
A method of preventing restenosis in a blood vessel comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; a radiation emitting source disposed within the catheter distal portion, the radiation emitting source comprising 90 Yttrium adapted to irradiate a blood vessel wall without substantially irradiating tissue beyond the blood vessel wall; and a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially center the radiation emitting source in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the radiation emitting source essentially radially centered within a blood vessel formed of a blood vessel wall; and (c) irradiating the blood wall without substantially irradiating tissue beyond the blood vessel wall.
Claim 50
Independent Claim 120 words
A method of preventing restenosis in a blood vassal comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; a radiation emitting filament comprising 90 Yttrium disposed within the catheter distal portion and having a diameter less than 0.2 mm; and a balloon surrounding at least part of the catheter distal portion, and adapted to radially expand and essentially radially center the radiation emitting filament in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the radiation emitting filament essentially radially centered within a blood vessel; and (c) irradiating the treatment site.
Claim 51
Independent Claim 120 words
A method of preventing restenosis in a blood vassal comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; a radiation emitting filament comprising 90 Yttrium disposed within the catheter distal portion and having a diameter less than 0.2 mm; and a balloon surrounding at least part of the catheter distal portion, and adapted to radially expand and essentially radially center the radiation emitting filament in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the radiation emitting filament essentially radially centered within a blood vessel; and (c) irradiating the treatment site.
Claim 52
Independent Claim 105 words
A method of preventing restenosis in a blood vessel comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; 90 Yttrium disposed within the catheter distal portion; and a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the 90 Yttrium in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the 90 Yttrium essentially radially centered within a blood vessel; and (c) irradiating the treatment site.
Claim 53
Independent Claim 105 words
A method of preventing restenosis in a blood vessel comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; 90 Yttrium disposed within the catheter distal portion; and a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the 90 Yttrium in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the 90 Yttrium essentially radially centered within a blood vessel; and (c) irradiating the treatment site.

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2003-06-13 2003-12-13 2004-06-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2007-06-13 2007-12-13 2008-06-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2011-06-13 2011-12-13 2012-06-13 $7700.00 Window Closed / Lapsed

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