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Patent US6061591A successfully refreshed from Google Patents.
US6061591A
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Arrangement and method for diagnosing malignant tissue by fluorescence observation
Assignee: Richard Wolf GmbH
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Filing: 1997-03-24
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Granted: 2000-05-09
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Expires: 2017-03-24
Abstract
Abstract The invention relates to an arrangement and method for diagnosing malignant tissue by fluorescence observation with an endoscope. A stroboscope is used as a white light source in order to illuminate the interesting tissue region through the endosocope. A laser is simultaneously used in order to stimulate the fluorescence. At a time, the analyzer is activated in the dark phase between two light flashes of the stroboscope and deactivated during a visible light flash. The tissue, with a continuous fluorescence stimulation by exposure to light with a stimulating wavelength, may be observed under a pseudo-white light. The spectrogram may be represented on a screen which displays a normal white light endoscopic picture.
Inventors
- 👤 Lutz Freitag
- 👤 Franz Dankwart-Eder
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 15:15
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/0059; A61B5/0082; A61B5/0084; A61B1/00; A61B1/00163; A61B1/00186; A61B1/04; A61B1/043; A61B1/06; A61B1/0638; A61B1/0646; A61B5/0071; Y; Y10; Y10S; Y10S607/00; Y10S607/901
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
110 words
An arrangement for diagnosing malignant tissue by fluorescence observation, comprising an endoscope (1), a white light source (3, 16, 37), a fluorescence stimulator (4, 35) for emitting a light beam, and an analyzer (5, 15, 43), wherein the fluorescence stimulator (4, 35) constantly emits a continuous light beam during a diagnosis, the white light source (3, 16, 37) comprises a device for effecting a periodic change of intensity of a visible light pulse emitted from the white light source (3, 16, 37), and the analyzer (5, 15, 43) is activated when the intensity of the visible light pulse approaches zero and is deactivated during emission of the visible light pulse.
Claim 2
Dependent Claim
110 words
An arrangement for diagnosing malignant tissue by fluorescence observation, comprising an endoscope (1), a white light source (3, 16, 37), a fluorescence stimulator (4, 35) for emitting a light beam, and an analyzer (5, 15, 43), wherein the fluorescence stimulator (4, 35) constantly emits a continuous light beam during a diagnosis, the white light source (3, 16, 37) comprises a device for effecting a periodic change of intensity of a visible light pulse emitted from the white light source (3, 16, 37), and the analyzer (5, 15, 43) is activated when the intensity of the visible light pulse approaches zero and is deactivated during emission of the visible light pulse.
Claim 3
Dependent Claim
17 words
The arrangement according to claim 1, wherein the white light source (3, 16, 37) comprises a stroboscope.
Claim 4
Dependent Claim
14 words
The arrangement according to claim 2, wherein the fluorescence stimulator (4) comprises a laser.
Claim 5
Dependent Claim
14 words
The arrangement according to claim 2, wherein the fluorescence stimulator comprises an arc lamp.
Claim 6
Dependent Claim
34 words
The arrangement according to claim 2, further comprising a filter (19, 42) arranged adjacent to the analyzer (5, 15, 43) for selectively blanking out a stimulation wavelength emitted from the fluorescence stimulator (4, 35).
Claim 7
Dependent Claim
14 words
The arrangement according to claim 1, wherein the fluorescence stimulator (4) comprises a laser.
Claim 8
Dependent Claim
34 words
The arrangement according to claim 6, further comprising a filter (19, 42) arranged adjacent to the analyzer (5, 15, 43) for selectively blanking out a stimulation wavelength emitted from the fluorescence stimulator (4, 35).
Claim 9
Dependent Claim
14 words
The arrangement according to claim 1, wherein the fluorescence stimulator comprises an arc lamp.
Claim 10
Dependent Claim
34 words
The arrangement according to claim 8, further comprising a filter (19, 42) arranged adjacent to the analyzer (5, 15, 43) for selectively blanking out a stimulation wavelength emitted from the fluorescence stimulator (4, 35).
Claim 11
Dependent Claim
34 words
The arrangement according to claim 1, further comprising a filter (19, 42) arranged adjacent to the analyzer (5, 15, 43) for selectively blanking out a stimulation wavelength emitted from the fluorescence stimulator (4, 35).
Claim 12
Independent Claim
91 words
A method for diagnosing malignant tissue by fluorescence observation, comprising exposing a tissue to be observed to a continuous fluorescence stimulation by a light beam with a stimulation wavelength, simultaneously observing the tissue under light pulses (B) produced by a stroboscope (3, 16, 37), and analyzing a wavelength of fluorescence emitted from the tissue, wherein an analyzer (5, 15, 43) for conducting the analysis is deactivated during each of the light pulses (B) and is activated during a period of a dark phase (D) between two of the light pulses (B).
Claim 13
Independent Claim
91 words
A method for diagnosing malignant tissue by fluorescence observation, comprising exposing a tissue to be observed to a continuous fluorescence stimulation by a light beam with a stimulation wavelength, simultaneously observing the tissue under light pulses (B) produced by a stroboscope (3, 16, 37), and analyzing a wavelength of fluorescence emitted from the tissue, wherein an analyzer (5, 15, 43) for conducting the analysis is deactivated during each of the light pulses (B) and is activated during a period of a dark phase (D) between two of the light pulses (B).
Claim 14
Dependent Claim
30 words
The method according to claim 11, wherein the wavelength emitted by the tissue (2) corresponds to the stimulation wavelength and is selectively blanked out before the analyzer (5, 15, 43).
References Cited (Backward Citations)
US4556057A
Cited
US4768513A
Cited
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