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Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas

Assignee: University of California, San Diego
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Filing: 1997-10-06
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Granted: 2000-01-04
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Expires: 2017-10-06
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Abstract

Abstract An artery, vein, aneurysm, vascular malformation or arterial fistula is occluded through endovascular occlusion by the endovascular insertion of a platinum wire and/or tip into the vascular cavity. The vascular cavity is packed with the tip to obstruct blood flow or access of blood in the cavity such that the blood clots in the cavity and an occlusion if formed. The tip may be elongate and flexible so that it packs the cavity by being folded upon itself a multiple number of times, or may pack the cavity by virtue of a filamentary or fuzzy structure of the tip. The tip is then separated from the wire mechanically or by electrolytic separation of the tip from the wire. The wire and the microcatheter are thereafter removed leaving the tip embedded in the thrombus formed within the vascular cavity. Movement of wire in the microcatheter is more easily tracked by providing a radioopaque proximal marker on the microcatheter and a corresponding indicator marker on the wire. Electrothrombosis is facilitate by placing the ground electrode on the distal end of the microcatheter and flowing current between the microcatheter electrode and the tip.

Inventors

  • 👤 Guido Guglielmi

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 18:40
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/01; A61M25/09; A61B; A61B17/00; A61B17/12; A61B17/12022; A61B17/12099; A61B17/12109; A61B17/12113; A61B17/12131; A61B17/1214; A61B17/12145; A61B17/1215; A61B17/12168; A61B17/12172; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/1492; A61B17/00234; A61B2017/00292; A61B2017/1205; A61B2017/12054; A61B2017/12063; A61B2017/12095; A61B17/22; A61B2017/22038; A61B2018/00636; A61B2018/00666; A61B2018/00678; A61B2018/00696; A61B2018/00761; A61B2018/00773; A61B2018/00875; A61B2018/00886; A61B18/1206; A61B2018/1226; A61B2018/1246; A61B2018/1253; A61B2018/126; A61B2018/1266; A61B2018/1405; A61B2018/1435; A61B2018/1495; A61B90/00; A61B90/39; A61B2090/3966; A61M2025/09175

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 205 words
An apparatus for forming an occlusion within a body cavity comprising: a catheter; a wire; and a detachable elongate tip portion coupled to a distal portion of said wire which is retrievable until detached, said tip portion being adapted to be positioned in said body cavity to form an occlusion in said body cavity using one or more implantations of detachable elongate tip portions from corresponding wires, said wire having a radioopaque marker disposed thereon proximal on said wire from a detachment point of said elongate tip portion from said wire by a predetermined distance, said catheter having two radioopaque markers disposed thereon and spaced apart from each other, wherein one of said two markers on said catheter is provided at a distal end of said catheter and said other marker is positioned proximally thereof, wherein said radioopaque markers are disposed on said wire and said catheter so that when said marker at said distal end of said catheter is disposed adjacent to an opening of said body cavity and when said wire is telescopically disposed in said catheter to approximately align said wire's radioopaque marker with said more proximal catheter marker, said detachable elongate tip portion then is fully disposed in said body cavity.
Claim 2
Independent Claim 205 words
An apparatus for forming an occlusion within a body cavity comprising: a catheter; a wire; and a detachable elongate tip portion coupled to a distal portion of said wire which is retrievable until detached, said tip portion being adapted to be positioned in said body cavity to form an occlusion in said body cavity using one or more implantations of detachable elongate tip portions from corresponding wires, said wire having a radioopaque marker disposed thereon proximal on said wire from a detachment point of said elongate tip portion from said wire by a predetermined distance, said catheter having two radioopaque markers disposed thereon and spaced apart from each other, wherein one of said two markers on said catheter is provided at a distal end of said catheter and said other marker is positioned proximally thereof, wherein said radioopaque markers are disposed on said wire and said catheter so that when said marker at said distal end of said catheter is disposed adjacent to an opening of said body cavity and when said wire is telescopically disposed in said catheter to approximately align said wire's radioopaque marker with said more proximal catheter marker, said detachable elongate tip portion then is fully disposed in said body cavity.
Claim 3
Dependent Claim 40 words
The combination of claim 1 wherein full deployment of said detachable elongate tip portion in said body cavity positions a coupling of said detachable elongate tip portion to said wire approximately 2-3 mm past said opening of said body cavity.
Claim 4
Dependent Claim 31 words
The combination of claim 1 wherein said detachable elongate tip portion is a long and substantially pliable segment adapted to be multiply folded upon itself to substantially pack said body cavity.
Claim 5
Dependent Claim 16 words
The combination of claim 1 wherein said detachable elongate tip portion is 4-40 cm in length.
Claim 6
Dependent Claim 17 words
The combination of claim 1 wherein said wire and detachable elongate tip portion are coupled by polyester.
Claim 7
Dependent Claim 22 words
The combination of claim 1 wherein said tip portion is detachable from said wire by electrolytic disintegration of part of said wire.
Claim 8
Independent Claim 200 words
An apparatus for forming an occlusion within a body cavity comprising: a catheter with a proximal end and a distal end; a wire; and a detachable elongate tip portion coupled to a distal portion of said wire which is retrievable until detached, said detachable elongate tip portion having a proximal end when detached from said wire, said tip portion being adapted to be positioned in said body cavity to form an occlusion in said body cavity using one or more implantations of detachable elongate tip portions from corresponding wires, said wire having a radioopaque marker disposed on said wire a predetermined distance from a detachment section of said elongate tip portion from said wire, said catheter having at least one radioopaque marker disposed thereon, wherein said radioopaque markers are disposed on said wire and said catheter so that when said distal end of said catheter is positioned at an opening of said body cavity to be occluded and said wire is telescopically disposed in said catheter to approximately align said radioopaque marker on said wire with said radioopaque marker on said catheter, said proximal end of said detachable elongate tip portion is then disposed when detached within said body cavity.
Claim 9
Independent Claim 200 words
An apparatus for forming an occlusion within a body cavity comprising: a catheter with a proximal end and a distal end; a wire; and a detachable elongate tip portion coupled to a distal portion of said wire which is retrievable until detached, said detachable elongate tip portion having a proximal end when detached from said wire, said tip portion being adapted to be positioned in said body cavity to form an occlusion in said body cavity using one or more implantations of detachable elongate tip portions from corresponding wires, said wire having a radioopaque marker disposed on said wire a predetermined distance from a detachment section of said elongate tip portion from said wire, said catheter having at least one radioopaque marker disposed thereon, wherein said radioopaque markers are disposed on said wire and said catheter so that when said distal end of said catheter is positioned at an opening of said body cavity to be occluded and said wire is telescopically disposed in said catheter to approximately align said radioopaque marker on said wire with said radioopaque marker on said catheter, said proximal end of said detachable elongate tip portion is then disposed when detached within said body cavity.
Claim 10
Dependent Claim 40 words
The combination of claim 7 wherein full deployment of said detachable elongate tip portion in said body cavity positions a coupling of said detachable elongate tip portion to said wire approximately 2-3 mm past said opening of said body cavity.
Claim 11
Dependent Claim 31 words
The combination of claim 7 wherein said detachable elongate tip portion is a long and substantially pliable segment adapted to be multiply folded upon itself to substantially pack said body cavity.
Claim 12
Dependent Claim 16 words
The combination of claim 7 wherein said detachable elongate tip portion is 4-40 cm in length.
Claim 13
Dependent Claim 17 words
The combination of claim 7 wherein said wire and detachable elongate tip portion are coupled by polyester.
Claim 14
Dependent Claim 22 words
The combination of claim 7 wherein said tip portion is detachable from said wire by electrolytic disintegration of part of said wire.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2003-01-03 2003-07-05 2004-01-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2007-01-03 2007-07-05 2008-01-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2011-01-03 2011-07-05 2012-01-04 $7700.00 Window Closed / Lapsed

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