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US5947962A Expired / Lapsed US ⏱️ 0.0 years remaining

Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries veins aneurysms vascular malformations and arteriovenous fistulas

Assignee: University of California, San Diego
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Filing: 1997-10-06
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Granted: 1999-09-07
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Expires: 2017-10-06
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Abstract

Abstract An artery, vein, aneurysm, vascular malformation or arterial fistula is occluded through endovascular occlusion by the endovascular insertion of a platinum wire and/or tip into the vascular cavity. The vascular cavity is packed with the tip to obstruct blood flow or access of blood in the cavity such that the blood clots in the cavity and an occlusion if formed. The tip may be elongate and flexible so that it packs the cavity by being folded upon itself a multiple number of times, or may pack the cavity by virtue of a filamentary or fuzzy structure of the tip. The tip is then separated from the wire mechanically or by electrolytic separation of the tip from the wire. The wire and the microcatheter are thereafter removed leaving the tip embedded in the thrombus formed within the vascular cavity. Movement of wire in the microcatheter is more easily tracked by providing a radioopaque proximal marker on the microcatheter and a corresponding indicator marker on the wire. Electrothrombosis is facilitate by placing the ground electrode on the distal end of the microcatheter and flowing current between the microcatheter electrode and the tip.

Inventors

  • 👤 Guido Guglielmi
  • 👤 Ivan Sepetka

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 12:54
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/01; A61M25/09; A61B; A61B17/00; A61B17/12; A61B17/12022; A61B17/12099; A61B17/12109; A61B17/12113; A61B17/12131; A61B17/1214; A61B17/12145; A61B17/1215; A61B17/12168; A61B17/12172; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/1492; A61B17/00234; A61B2017/00292; A61B2017/1205; A61B2017/12054; A61B2017/12063; A61B2017/12095; A61B17/22; A61B2017/22038; A61B2018/00636; A61B2018/00666; A61B2018/00678; A61B2018/00696; A61B2018/00761; A61B2018/00773; A61B2018/00875; A61B2018/00886; A61B18/1206; A61B2018/1226; A61B2018/1246; A61B2018/1253; A61B2018/126; A61B2018/1266; A61B2018/1405; A61B2018/1435; A61B2018/1495; A61B90/00; A61B90/39; A61B2090/3966; A61M2025/09175

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 142 words
A catheter wire for use in electrothrombosis in combination with a microcatheter comprising: a core wire having a main body and a distal portion, said distal portion being susceptible to electrolytic disintegration; and a detachable coil for insertion within a body cavity, said detachable coil being coupled to said main body via said distal portion, being comprised of material not susceptible to electrolytic disintegration, and being prebiased to a spiral or helical shape such that on its advancement out of the distal end of a microcatheter and into a cavity it will change from being straight to its prebiased spiral or helical shape so that on the application of current to said detachable coil disposed in the cavity, electrothrombosis can be performed and at least one portion of said distal portion electrolytically disintegrated to detach said detachable coil from said main body.
Claim 2
Dependent Claim 142 words
A catheter wire for use in electrothrombosis in combination with a microcatheter comprising: a core wire having a main body and a distal portion, said distal portion being susceptible to electrolytic disintegration; and a detachable coil for insertion within a body cavity, said detachable coil being coupled to said main body via said distal portion, being comprised of material not susceptible to electrolytic disintegration, and being prebiased to a spiral or helical shape such that on its advancement out of the distal end of a microcatheter and into a cavity it will change from being straight to its prebiased spiral or helical shape so that on the application of current to said detachable coil disposed in the cavity, electrothrombosis can be performed and at least one portion of said distal portion electrolytically disintegrated to detach said detachable coil from said main body.
Claim 3
Dependent Claim 131 words
The catheter wire of claim 1 wherein said distal portion is exposed stainless steel coil having a proximal end and a distal end connected at its proximal end to said core wire and connected at its distal end to said detachable coil, and wherein said distal portion further comprises a threadlike extension of said main body of said core wire extending concentrically within said stainless steel coil, said threadlike extension having a distal end and being connected at said distal end of said threadlike extension to a connection between said distal end of said stainless steel coil and said detachable coil, both said threadlike extension and said stainless steel coil needing to be electrolytically disintegrated at least at one point in order to detach said detachable coil from said main body.
Claim 4
Dependent Claim 59 words
The catheter wire of claim 1 wherein said distal portion is exposed stainless steel coil having a proximal end and a distal end connected at its proximal end to said core wire and connected at its distal end to said detachable coil and wherein said stainless steel coil defines an interior space, said interior space being free and unreinforced.
Claim 5
Dependent Claim 16 words
The catheter wire of claim 1 wherein said detachable coil is a long and pliable segment.
Claim 6
Dependent Claim 22 words
The catheter wire of claim 1 wherein said detachable coil has a length sufficient to substantially fill said cavity when disposed therein.
Claim 7
Dependent Claim 20 words
The catheter wire of claim 1 wherein said detachable coil is comprised of a metal not susceptible to electrolytic disintegration.
Claim 8
Dependent Claim 16 words
The catheter wire of claim 1 wherein said detachable coil does not contain any internal reinforcement.
Claim 9
Dependent Claim 17 words
The catheter wire of claim 1 wherein said detachable coil is prebiased to have a conical envelope.
Claim 10
Dependent Claim 17 words
The catheter wire of claim 1 wherein said detachable coil is prebiased to have a cylindrical envelope.
Claim 11
Dependent Claim 43 words
The catheter wire of claim 1 wherein although prebiased said detachable coil is extremely soft and its overall shape is easily deformed such that, once advanced from a microcatheter into said cavity, it will loosely deform to said interior shape of said cavity.
Claim 12
Dependent Claim 32 words
The catheter wire of claim 1 wherein said main body of said core wire is covered with insulation to prevent said underlying portion of said guidewire from coming into contact with fluid.
Claim 13
Dependent Claim 83 words
The catheter wire of claim 1 wherein said distal portion of said core wire is such that, when said detachable coil is disposed in said cavity and a current of approximately 0.01 to 2 milliamps to said guidewire at 0.1 to 6 volts is supplied to said guidewire, disintegration of said at least one portion of said distal portion of said core wire takes place within 3 to 10 minutes to detach said detachable coil from said main body of said core wire.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2002-09-06 2003-03-08 2003-09-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2006-09-06 2007-03-08 2007-09-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2010-09-06 2011-03-08 2011-09-07 $7700.00 Window Closed / Lapsed

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