US5122136A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Endovascular electrolytically detachable guidewire tip for the electroformation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
Assignee: BLOSSOM FLOWER Inc
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Filing: 1990-03-13
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Granted: 1992-06-16
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Expires: 2010-03-13
Abstract
Abstract An artery, vein, aneurysm, vascular malformation or arterial fistula is occluded through endovascular electrothrombosis by the endovascular insertion of a platinum guidewire tip into the vascular cavity followed by application of a positive current. The guidewire tip is then separated from the guidewire by electrolytic separation of the tip from the guidewire. A portion of the guidewire connected between the tip and the body of the guidewire is comprised of stainless steel and exposed to the bloodstream so that upon continued application of a positive current to the exposed portion, the exposed portion is corroded away at least at one location and the tip is separated from the body of the guidewire. The guidewire and the microcatheter are thereafter removed leaving the guidewire tip embedded in the thrombus formed within the vascular cavity.
Inventors
- 👤 Guido Guglielmi
- 👤 Ivan Sepetka
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:09
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/01; A61M25/09; A61B; A61B18/00; A61B17/00; A61B17/12; A61B17/12022; A61B17/12099; A61B17/12109; A61B17/12113; A61B17/12131; A61B17/1214; A61B17/12145; A61B17/1215; A61B18/04; A61B18/12; A61B18/14; A61B18/1492; A61B17/00234; A61B2017/00292; A61B2017/1205; A61B2017/12054; A61B2017/12063; A61B17/22; A61B2017/22038; A61B2018/00636; A61B2018/00666; A61B2018/00678; A61B2018/00696; A61B2018/00761; A61B2018/00773; A61B2018/00875; A61B2018/00886; A61B18/1206; A61B2018/1226; A61B2018/1246; A61B2018/1253; A61B2018/126; A61B2018/1266; A61B2018/1405; A61B2018/1435; A61B2018/1495; A61B90/00; A61B90/39; A61B2090/3966; A61M25/0021; A61M2025/0042; A61M2025/09175
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
98 words
A method for forming an occlusion within a vascular cavity having blood disposed therein comprising the steps of: endovascularly disposing a guidewire near an endovascular opening into said vascular cavity; disposing a distal tip of said guidewire into said vascular cavity to form said occlusion within said vascular cavity about said distal tip; and detaching said distal tip from said guidewire to leave said distal tip within said vascular cavity and said occlusion being formed within said vascular cavity, whereby said vascular cavity is occluded by said distal tip, and any thrombus formed by use of said tip.
Claim 2
Independent Claim
98 words
A method for forming an occlusion within a vascular cavity having blood disposed therein comprising the steps of: endovascularly disposing a guidewire near an endovascular opening into said vascular cavity; disposing a distal tip of said guidewire into said vascular cavity to form said occlusion within said vascular cavity about said distal tip; and detaching said distal tip from said guidewire to leave said distal tip within said vascular cavity and said occlusion being formed within said vascular cavity, whereby said vascular cavity is occluded by said distal tip, and any thrombus formed by use of said tip.
Claim 3
Dependent Claim
31 words
The method of claim 1 where said step of disposing said distal tip in said vascular cavity further comprises the step of substantially occupying said vascular cavity with said distal tip.
Claim 4
Dependent Claim
32 words
The method of claim 2 where said step of substantially occupying said vascular cavity comprises the step of filling said vascular cavity with a long and pliable length of said distal tip.
Claim 5
Dependent Claim
28 words
The method of claim 1 wherein said step of detaching said distal tip from said guidewire comprises the step of electrolytically detaching said distal tip from said guidewire.
Claim 6
Dependent Claim
39 words
The method of claim 4 where said step of electrolytically detaching said distal tip from said guidewire comprises the step of electrolytically disintegrating at least one portion of a connecting segment extending between said guidewire and said distal tip.
Claim 7
Dependent Claim
29 words
The method of claim 5 where said step of electrolytically disintegrating said connecting segment comprises the step of electrolytically corroding away at least a portion of a coil segment.
Claim 8
Dependent Claim
25 words
The method of claim 6 where said step of electrolytically corroding said coil segment comprises the step of electrolytically disintegrating a stainless steel coil segment.
Claim 9
Dependent Claim
41 words
The method of claim 1 wherein said step of disposing said distal tip comprises the step of applying an electrical signal to said distal tip to form said thrombus by applying a positive direct current for a first predetermined time period.
Claim 10
Dependent Claim
42 words
The method of claim 8 wherein said step of detaching said distal tip from said guidewire comprises the step of applying a positive direct current to said distal tip for an additional predetermined time period separate from said first predetermined time period.
Claim 11
Dependent Claim
46 words
The method of claim 8 where in said step of detaching said distal tip from said guidewire, the location of detachment of said tip from said guidewire is unexposed during said first predetermined time period, and is exposed to blood during an additional predetermined time period.
Claim 12
Dependent Claim
34 words
The method of claim 1 wherein said step of detaching said distal tip from said guidewire comprises the step of applying a positive direct current to said distral tip for a predetermined time period.
Claim 13
Dependent Claim
96 words
The method of claim 1 wherein said step of disposing said tip comprises the step of disposing said guidewire in a first position relative to said vascular cavity so that a disintegratable portion of said tip remains insulated from said blood during application of a first electrical signal to said tip, and where said step of detaching comprises moving said disintegratable portion of said tip to a second position where said disintegratable portion is exposed to said blood, applying a second electrical signal to said disintegratable portion to electrolytically dissolve said disintegratable portion in said blood.
Claim 14
Dependent Claim
100 words
A guidewire for use in formation of an occlusion within a vascular cavity used in combination with a microcatheter comprising: a core wire, said core wire having a distal portion susceptible to electrolytic distintegration in blood; and an elongate tip portion extending said core wire for a predetermined lineal extent adapted to form said occlusion in said vascular cavity and coupled to said distal portion of said core wire tip portion for endovascular insertion within a vascular cavity, said elongate tip portion not being susceptible to electrolytic disintegration in blood, whereby endovascular occlusion of said vascular cavity can be performed.
Claim 15
Dependent Claim
100 words
A guidewire for use in formation of an occlusion within a vascular cavity used in combination with a microcatheter comprising: a core wire, said core wire having a distal portion susceptible to electrolytic distintegration in blood; and an elongate tip portion extending said core wire for a predetermined lineal extent adapted to form said occlusion in said vascular cavity and coupled to said distal portion of said core wire tip portion for endovascular insertion within a vascular cavity, said elongate tip portion not being susceptible to electrolytic disintegration in blood, whereby endovascular occlusion of said vascular cavity can be performed.
Claim 16
Dependent Claim
19 words
The guidewire of claim 13 wherein said distal portion of said core wire is an exposed stainless steel segment.
Claim 17
Dependent Claim
43 words
The guidewire of claim 14 wherein said stainless steel segment comprises a coil having a proximate and distal end, and connected at its proximate end to said core wire and connected at its distal end to said elongate tip portion of said guidewire.
Claim 18
Dependent Claim
46 words
The guidewire of claim 15 wherein said core wire is extended in a threadlike portion concentrically within said stainless steel coil from a proximal end of said stainless steel coil to where said stainless steel coil is connected to said elongate tip portion of said guidewire.
Claim 19
Dependent Claim
19 words
The guideware of claim 15 wherein said coil defines an interior space, said interior space being free and unreinforced.
Claim 20
Dependent Claim
30 words
The guideware of claim 13 wherein said elongate tip portion is a long and substantially pliable segment and is comprised of a metal not susceptible to electrolytic disintegration within blood.
Claim 21
Dependent Claim
29 words
the guidewire of claim 18 wherein said long and pliable segment of said elongate tip portion has a length sufficient to substantially fill said vascular cavity when inserted therein.
Claim 22
Dependent Claim
16 words
The guidewire of claim 13 wherein said elongate tip portion is comprised of 479 platinum alloy.
Claim 23
Dependent Claim
131 words
A guidewire for use in formation of an occlusion used in combination with a microcatheter comprising: a core wire, said core wire having a distal portion susceptible to electrolytic disintegration in blood; and an elongate tip portion extending said core wire for a predetermined lineal extent and coupled to said distal portion of said core wire, said tip portion for endovascular insertion within a vascular cavity, said elongate tip portion not being susceptible to electrolytic disintegration in blood, wherein said elongate tip portion is a long and substantially pliable segment and is comprised of a mental not susceptible to electrolytic disintegration within blood, and wherein said long and pliable segment is prebiased to form a helix when extended from said microcatheter, whereby endovascular occlusion of said vascular cavity can be performed.
Claim 24
Dependent Claim
131 words
A guidewire for use in formation of an occlusion used in combination with a microcatheter comprising: a core wire, said core wire having a distal portion susceptible to electrolytic disintegration in blood; and an elongate tip portion extending said core wire for a predetermined lineal extent and coupled to said distal portion of said core wire, said tip portion for endovascular insertion within a vascular cavity, said elongate tip portion not being susceptible to electrolytic disintegration in blood, wherein said elongate tip portion is a long and substantially pliable segment and is comprised of a mental not susceptible to electrolytic disintegration within blood, and wherein said long and pliable segment is prebiased to form a helix when extended from said microcatheter, whereby endovascular occlusion of said vascular cavity can be performed.
Claim 25
Dependent Claim
12 words
the guidewire of claim 21 wherein said helix has a conical envelope.
Claim 26
Dependent Claim
12 words
The guidewire of claim 21 wherein said helix has a cylindrical envelope.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-06-16 | 1995-12-16 | 1996-06-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-06-16 | 1999-12-16 | 2000-06-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-06-16 | 2003-12-16 | 2004-06-16 | $7700.00 | Window Closed / Lapsed |