Patent US5892218A successfully refreshed from Google Patents.
← Back to Patent Explorer
US5892218A Expired / Lapsed US ⏱️ 0.0 years remaining

Cytological system autofocus integrity checking apparatus

Assignee: TriPath Imaging Inc
•
Filing: 1997-03-20
•
Granted: 1999-04-06
•
Expires: 2017-03-20
📄 Original PDF 🌐 Google Patents 🔄 Sync Now

Abstract

Abstract An automated method for checking cytological system autofocus integrity. The automated method includes the steps of checking focus illumination integrity, checking focus camera Modulation Transfer Function, checking focus camera position integrity, and checking closed loop accuracy. Checking focus illumination integrity includes checking focus illumination system integrity, and checking a focus noise floor level. Checking focus camera position integrity includes checking focus camera longitudinal separation, and checking focus camera lateral separation. Checking focus camera position integrity includes checking focus filter frequency response.

Inventors

  • 👤 William E. Ortyn
  • 👤 Jon W. Hayenga
  • 👤 Louis R. Piloco

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 07:45
CPC Classifications
H; H04; H04N; H04N7/00; H04N7/18; H04N7/183; G; G02; G02B; G02B21/00; G02B21/24; G02B21/241; G02B21/244; G02B7/00; G02B7/28; G02B7/36; H04N7/181; H04N7/188

Claims Analysis

Total Claims: 20
Claim 1
Independent Claim 118 words
A method for testing a focus noise floor in a system including a focus camera, further including a focus camera filter, the method comprising the steps of: (a) positioning an objective over a nominal clear area of a calibration plate; (b) acquiring an image of a uniformly illuminated clear field of the nominal clear area of the calibration plate; (c) acquiring noise scores for each video line of the focus camera filter; (d) processing the noise scores from the focus camera filter to determine a maximum noise score value for the focus camera filter as a focus noise floor for the focus camera; and (e) comparing the focus noise floor for the focus camera to a predetermined limit.
Claim 2
Independent Claim 118 words
A method for testing a focus noise floor in a system including a focus camera, further including a focus camera filter, the method comprising the steps of: (a) positioning an objective over a nominal clear area of a calibration plate; (b) acquiring an image of a uniformly illuminated clear field of the nominal clear area of the calibration plate; (c) acquiring noise scores for each video line of the focus camera filter; (d) processing the noise scores from the focus camera filter to determine a maximum noise score value for the focus camera filter as a focus noise floor for the focus camera; and (e) comparing the focus noise floor for the focus camera to a predetermined limit.
Claim 3
Dependent Claim 37 words
The method of claim 1 further comprising the steps of: (a) checking a mean illumination level for the focus camera against limits; and (b) checking a coefficient of variation of illumination for the focus camera against limits.
Claim 4
Dependent Claim 15 words
The method of claim 1 wherein the focus camera filter further comprises an electronic filter.
Claim 5
Dependent Claim 14 words
The method of claim 1 wherein the focus camera comprises a plus focus camera.
Claim 6
Dependent Claim 17 words
The method of claim 4 wherein the focus camera filter further comprises a plus focus camera filter.
Claim 7
Dependent Claim 23 words
The method of claim 5 further comprising the step of acquiring a plurality of focus noise floor levels for a focus plus response.
Claim 8
Dependent Claim 14 words
The method of claim 1 wherein the focus camera comprises a minus focus camera.
Claim 9
Dependent Claim 17 words
The method of claim 7 wherein the focus camera filter further comprises a minus focus camera filter.
Claim 10
Dependent Claim 23 words
The method of claim 8 further comprising the step of acquiring a plurality of focus noise floor levels for a focus minus response.
Claim 11
Dependent Claim 16 words
The method of claim 1 further comprising the step of optimizing the image for focus processing.
Claim 12
Dependent Claim 34 words
The method of claim 10 wherein the step of optimizing the image for focus processing further comprises the step of filtering out objects that do not have a characteristic frequency content of cellular nuclei.
Claim 13
Independent Claim 167 words
A method for testing a focus noise floor level in a system including a plus focus camera and a minus focus camera, further including a plus focus camera filter and a minus focus camera filter, the method comprising the steps of: (a) positioning an objective over a nominal clear area of a calibration plate; (b) checking a mean illumination level for the plus focus camera and the minus focus camera against limits; (c) checking a coefficient of variation of illumination for the plus focus camera and the minus focus camera against limits; (d) acquiring an image; (e) acquiring noise scores for each video line of the plus focus camera filter and the minus focus camera filter; (f) processing the noise scores from the plus focus camera filter and the minus focus camera filter to determine a maximum noise score value for each focus camera filter as a focus noise floor for each camera; and (g) comparing the focus noise floor for each camera to a predetermined limit.
Claim 14
Independent Claim 167 words
A method for testing a focus noise floor level in a system including a plus focus camera and a minus focus camera, further including a plus focus camera filter and a minus focus camera filter, the method comprising the steps of: (a) positioning an objective over a nominal clear area of a calibration plate; (b) checking a mean illumination level for the plus focus camera and the minus focus camera against limits; (c) checking a coefficient of variation of illumination for the plus focus camera and the minus focus camera against limits; (d) acquiring an image; (e) acquiring noise scores for each video line of the plus focus camera filter and the minus focus camera filter; (f) processing the noise scores from the plus focus camera filter and the minus focus camera filter to determine a maximum noise score value for each focus camera filter as a focus noise floor for each camera; and (g) comparing the focus noise floor for each camera to a predetermined limit.
Claim 15
Dependent Claim 16 words
The method of claim 12 wherein the plus focus camera filter further comprises an electronic filter.
Claim 16
Dependent Claim 16 words
The method of claim 12 wherein the minus focus camera filter further comprises an electronic filter.
Claim 17
Dependent Claim 16 words
The method of claim 12 further comprising the step of optimizing the image for focus processing.
Claim 18
Dependent Claim 34 words
The method of claim 15 wherein the step of optimizing the image for focus processing further comprises the step of filtering out objects that do not have a characteristic frequency content of cellular nuclei.
Claim 19
Dependent Claim 23 words
The method of claim 12 further comprising the step of acquiring a plurality of focus noise floor levels for a focus plus response.
Claim 20
Dependent Claim 23 words
The method of claim 12 further comprising the step of acquiring a plurality of focus noise floor levels for a focus minus response.

References Cited (Backward Citations)

US5134662A Cited
US4974092A Cited
US5077613A Cited
US5235428A Cited
US5357280A Cited
US5452005A Cited
US5499097A Cited
US5557097A Cited
US5647025A Cited
US5654535A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2002-04-05 2002-10-05 2003-04-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2006-04-05 2006-10-05 2007-04-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2010-04-05 2010-10-05 2011-04-06 $7700.00 Window Closed / Lapsed

Assigned Categories & Tags

No categories assigned to this patent yet.

Assign Category Tag