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Electrodes and electrode arrays for generating electroporation inducing electrical fields

Assignee: Ichor Medical Systems Inc
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Filing: 1997-04-24
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Granted: 1999-02-23
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Expires: 2017-04-24
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Abstract

Abstract Electrodes and electrode array apparatus and systems for in vivo delivery of electrical waveforms rendering therapeutic benefit to the patient by utilizing an electrode array having at least three individually addressable electrodes disposed so as to form a triangle in a plane intersecting the electrodes and an electrical signal generating device operatively connected to the electrodes for delivering electrical waveforms to said electrodes and generating electroporation-inducing electrical fields between the electrodes.

Inventors

  • 👤 Robert M. Bernard

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 20:22
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/0404; A61N1/0408; A61N1/0412; A61N1/0416; A61N1/0424; A61N1/0428; A61N1/0432; A61N1/044; A61N1/0472; A61N1/0476; A61N1/18; A61N1/32; A61N1/325; A61N1/326; A61N1/327; A61N1/20; A61N1/30; A61N1/303; A61N1/306

Claims Analysis

Total Claims: 26
Claim 1
Independent Claim 66 words
An apparatus for the delivery of electrical waveforms comprising: an electrode array having at least three individually addressable electrodes disposed so as to form a triangle in a plane intersecting said electrodes; and electrical signal generating means operatively connected to said individually-addressable electrodes for delivering electrical waveforms to said electrodes and generating electroporation-inducing electrical fields between said electrodes said at least three individually addressable electrodes simultaneously.
Claim 2
Independent Claim 66 words
An apparatus for the delivery of electrical waveforms comprising: an electrode array having at least three individually addressable electrodes disposed so as to form a triangle in a plane intersecting said electrodes; and electrical signal generating means operatively connected to said individually-addressable electrodes for delivering electrical waveforms to said electrodes and generating electroporation-inducing electrical fields between said electrodes said at least three individually addressable electrodes simultaneously.
Claim 3
Dependent Claim 12 words
An apparatus as recited in claim 1 wherein the electrodes are elongate.
Claim 4
Dependent Claim 17 words
An apparatus as recited in claim 2 wherein the elongate electrodes are oriented in approximately parallel directions.
Claim 5
Dependent Claim 15 words
An apparatus as recited in claim 1 wherein the triangle is of approximately equilateral geometry.
Claim 6
Dependent Claim 22 words
An apparatus as recited in claim 1 wherein each of said electrodes comprises an electrically conductive region and an electrically nonconductive region.
Claim 7
Dependent Claim 29 words
An apparatus as recited in claim 1 wherein said array comprises at least four electrodes disposed so as to form two interconnected triangles in a plane intersecting said electrodes.
Claim 8
Independent Claim 74 words
A system for the delivery of electrical waveforms to a patient comprising: means for implanting in a patient an electrode array having at least three individually addressable electrodes disposed so as to form a triangle in a plane intersecting said electrodes; and electrical signal generating means operatively connected to said individually-addressable electrodes for delivering electrical waveforms to said electrodes and generating electroporation-inducing electrical fields between said said at least three individually addressable electrodes simultaneously.
Claim 9
Independent Claim 74 words
A system for the delivery of electrical waveforms to a patient comprising: means for implanting in a patient an electrode array having at least three individually addressable electrodes disposed so as to form a triangle in a plane intersecting said electrodes; and electrical signal generating means operatively connected to said individually-addressable electrodes for delivering electrical waveforms to said electrodes and generating electroporation-inducing electrical fields between said said at least three individually addressable electrodes simultaneously.
Claim 10
Dependent Claim 12 words
A system as recited in claim 7 wherein the electrodes are elongate.
Claim 11
Dependent Claim 17 words
A system as recited in claim 8 wherein the elongate electrodes are oriented in approximately parallel directions.
Claim 12
Dependent Claim 15 words
A system as recited in claim 7 wherein the triangle is of approximately equilateral geometry.
Claim 13
Dependent Claim 22 words
A system as recited in claim 7 wherein each of said electrodes comprises an electrically conductive region and an electrically nonconductive region.
Claim 14
Dependent Claim 29 words
A system as recited in claim 11 wherein the electrically conductive region of said electrodes and the geometry of said array define a predetermined treatment area for said patient.
Claim 15
Dependent Claim 29 words
A system as recited in claim 7 wherein said array comprises at least four electrodes disposed so as to form two interconnected triangles in a plane intersecting said electrodes.
Claim 16
Independent Claim 78 words
An apparatus for the delivery of electrical waveforms comprising: an electrode array having at least four individually addressable electrodes disposed so as to form a plurality or triangles in a plane intersecting said electrodes wherein each such triangle shares a common side with an adjacent triangle; and electrical signal generating means operatively connected to said individually-addressable electrodes for delivering electrical waveforms to said electrodes and generating electroporation-inducing electrical fields between said at least three individually addressable electrodes simultaneously.
Claim 17
Independent Claim 78 words
An apparatus for the delivery of electrical waveforms comprising: an electrode array having at least four individually addressable electrodes disposed so as to form a plurality or triangles in a plane intersecting said electrodes wherein each such triangle shares a common side with an adjacent triangle; and electrical signal generating means operatively connected to said individually-addressable electrodes for delivering electrical waveforms to said electrodes and generating electroporation-inducing electrical fields between said at least three individually addressable electrodes simultaneously.
Claim 18
Independent Claim 105 words
An apparatus for the delivery of electrical waveforms comprising: a plurality of elongate individually addressable electrodes each having a proximal end and a distal end and comprising: means for connecting the proximal end of each said electrode to a source of electrical signals, an electrically conductive region located distal to said connecting means, and at least one of said electrodes having an electrically nonconductive region located adjacent to said connecting means; and electrical signal generating means operatively connected to said individually-addressable electrodes for delivering electrical waveforms to said electrodes and thereby generating electroporation-inducing electrical fields between said said at least three individually addressable electrodes simultaneously.
Claim 19
Independent Claim 105 words
An apparatus for the delivery of electrical waveforms comprising: a plurality of elongate individually addressable electrodes each having a proximal end and a distal end and comprising: means for connecting the proximal end of each said electrode to a source of electrical signals, an electrically conductive region located distal to said connecting means, and at least one of said electrodes having an electrically nonconductive region located adjacent to said connecting means; and electrical signal generating means operatively connected to said individually-addressable electrodes for delivering electrical waveforms to said electrodes and thereby generating electroporation-inducing electrical fields between said said at least three individually addressable electrodes simultaneously.
Claim 20
Dependent Claim 73 words
An apparatus for the delivery of electrical waveforms according to claim 15, wherein the plurality of elongate individually addressable electrodes comprises an electrode array having at least three individually addressable electrodes which are disposed so as to form a triangle in a plane intersecting said electrodes, whereby the disposition of the electrodes and the electrically conductive regions of the electrodes determine a three-dimensional region wherein the electrical waveforms propagate an electric field therebetween.
Claim 21
Dependent Claim 48 words
A system for the delivery of electrical waveforms to a patient according to claim 16 further comprising means for implanting said electrode array in a patient so that a three-dimensional region of tissue is established wherein the electrical waveforms propagate an electric field substantially confined to said region.
Claim 22
Independent Claim 76 words
A system for the delivery of electrical waveforms to a patient comprising: means for implanting in a patient an electrode array having at least three individually addressable electrodes disposed so as to form a triangle in a plane intersecting said electrodes; and electrical signal generating means operatively connected to said individually-addressable electrodes for delivering electrical waveforms to said electrodes and generating electroporation-inducing electrical fields between at least one reference electrode and a plurality of satellite electrodes.
Claim 23
Independent Claim 76 words
A system for the delivery of electrical waveforms to a patient comprising: means for implanting in a patient an electrode array having at least three individually addressable electrodes disposed so as to form a triangle in a plane intersecting said electrodes; and electrical signal generating means operatively connected to said individually-addressable electrodes for delivering electrical waveforms to said electrodes and generating electroporation-inducing electrical fields between at least one reference electrode and a plurality of satellite electrodes.
Claim 24
Dependent Claim 19 words
A system as recited in claim 18 wherein the electrodes are elongate and are oriented in approximately parallel directions.
Claim 25
Dependent Claim 27 words
A system as recited in claim 18 wherein the electrodes are elongate and each of said electrodes comprises an electrically conductive region and an electrically nonconductive region.
Claim 26
Dependent Claim 29 words
A system as recited in claim 20 wherein the electrically conductive region of said electrodes and the geometry of said array define a predetermined treatment area for said patient.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2002-02-22 2002-08-24 2003-02-23 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2006-02-22 2006-08-24 2007-02-23 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2010-02-22 2010-08-24 2011-02-23 $7700.00 Window Closed / Lapsed

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