Patent US5814020A successfully refreshed from Google Patents.
US5814020A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Medicament delivery device
Assignee: Alkermes Pharma Ireland Ltd
•
Filing: 1996-09-06
•
Granted: 1998-09-29
•
Expires: 2016-09-06
Abstract
Abstract A medicament delivery device has a reservoir within a housing and means for driving medicament from the reservoir. The device is provided with a filling mechanism upon which a medicament container sealed by a penetrable stopper is mounted. The mechanism comprises an internal bore which accommodates an internal rod from which a needle projects. Needle is hollow and is in communication with the reservoir. In order to fill the reservoir, the container is pressed into the bore, causing the needle to pierce the stopper, the stopper abutting against the rod and acting as a piston to drive medicament from the container as the container is pushed into the bore and moves relative to the stopper. Thus, the reservoir can be filled with the sterile medicament which is stable when stored in the container, and the filling is easily accomplished without the use of a syringe. A further advantageous feature is provided by a delivery needle which is mounted on the periphery of the lower surface of the housing. This configuration allows the driving means to be located adjacent to the skin, thereby, providing a more stable temperature and more predictable operation of the device.
Inventors
- 👤 Joseph Gross
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 08:31
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/142; A61M5/14244; A61M5/14248; A61M5/145; A61M5/14586; A61M5/14593; A61M2005/14204; A61M2005/14252; A61M2005/1426; A61M2005/14264
Claims Analysis
Total Claims: 66
Claim 1
Independent Claim
90 words
A medicament delivery device comprising a housing, a reservoir within the housing, a filling mechanism for the reservoir integral with the housing and gas generated means for driving the medicament from the filled reservoir, the filling mechanism being adapted to receive a container for the medicament, said container being sealed by a penetrable stopper, and the filling mechanism comprising means for penetrating the stopper, said penetrating means being in communication with the reservoir to allow the medicament to be transferred from the container to the reservoir via the filling mechanism.
Claim 2
Dependent Claim
90 words
A medicament delivery device comprising a housing, a reservoir within the housing, a filling mechanism for the reservoir integral with the housing and gas generated means for driving the medicament from the filled reservoir, the filling mechanism being adapted to receive a container for the medicament, said container being sealed by a penetrable stopper, and the filling mechanism comprising means for penetrating the stopper, said penetrating means being in communication with the reservoir to allow the medicament to be transferred from the container to the reservoir via the filling mechanism.
Claim 3
Dependent Claim
33 words
A medicament delivery device according to claim 1, wherein the medicament is provided in the form of a solid material which is reconstituted to a liquid form prior to use of the device.
Claim 4
Dependent Claim
17 words
A medicament delivery device according to claim 2, wherein the medicament is provided as a lyophilised solid.
Claim 5
Dependent Claim
26 words
A medicament delivery device according to claim 3, wherein a portion of the housing is transparent or translucent thereby allowing visual inspection of the reservoir contents.
Claim 6
Dependent Claim
28 words
A medicament delivery device according to claim 4, wherein said cover is provided with a snap mechanism allowing it to snap between a first and a second position.
Claim 7
Dependent Claim
35 words
A medicament delivery device according to claim 1, wherein the housing has a skin-contacting surface, and further comprising a hollow needle communicating with the reservoir extending, in use, through the periphery of the skin-contacting surface.
Claim 8
Dependent Claim
21 words
A medicament delivery device according to claim 6, wherein the driving means is located intermediate the reservoir and the skin-contacting surface.
Claim 9
Dependent Claim
25 words
A medicament delivery device according to claim 7, wherein the driving means has a substantially flat configuration and is disposed parallel to the skin-contacting surface.
Claim 10
Dependent Claim
60 words
A medicament delivery device according to claim 6, wherein the skin-contacting surface is in the form of a cover attached to the housing, said cover being movable between first and second positions, the needle being concealed by said cover when the cover is in said first position, and the needle being exposed when the cover is in said second position.
Claim 11
Dependent Claim
20 words
A medicament delivery device according to claim 9, wherein said cover is mounted on the housing by a hinge mechanism.
Claim 12
Dependent Claim
19 words
A medicament delivery device according to claim 6, wherein the driving means is located immediately above the skin-contacting surface.
Claim 13
Dependent Claim
21 words
A medicament delivery device according to claim 1, wherein the gas generating apparatus is in the form of an electrolytic cell.
Claim 14
Dependent Claim
23 words
A medicament delivery device according to claim 12, wherein the electrolytic cell comprises upper and lower plates and an electrolyte intermediate said plates.
Claim 15
Dependent Claim
16 words
A medicament delivery device according to claim 13, wherein the electrolytic cell further comprises a battery.
Claim 16
Dependent Claim
29 words
A medicament delivery device according to claim 12, wherein the electrolytic cell comprises a reservoir for a liquid electrolyte bounded in part by a gas permeable, liquid impermeable membrane.
Claim 17
Dependent Claim
16 words
A medicament delivery device according to claim 15, wherein the electrolytic cell further comprises a battery.
Claim 18
Dependent Claim
65 words
A medicament delivery device according to claim 1, wherein the housing is provided with a bore which receives the container and the penetrating means is disposed on a stop within the bore, such that the stopper is penetrated and abuts against the stop when the container is pushed along the bore, the penetrated stopper acting as a piston to deliver the medicament from the container.
Claim 19
Dependent Claim
40 words
A medicament delivery device according to claim 17, wherein the penetrating means comprises a hollow needle and the stop is a rod extending within the bore, the needle communicating with the reservoir via a conduit extending internally of the rod.
Claim 20
Dependent Claim
26 words
A medicament delivery device according to claim 1, wherein the gas generating apparatus comprises two substances which when brought into contact react to generate a gas.
Claim 21
Dependent Claim
17 words
A medicament delivery device according to claim 19, wherein the substances are an acid and a base.
Claim 22
Dependent Claim
16 words
A medicament delivery device according to claim 1, wherein the driving means comprises a swellable gel.
Claim 23
Dependent Claim
40 words
A medicament delivery device according to claim 21, wherein the swellable gel swells on contact with a liquid and the driving means further comprises a container containing such a liquid, and means for bringing the liquid and gel into contact.
Claim 24
Dependent Claim
35 words
A medicament delivery device according to claim 1, wherein the container protrudes from the housing prior to use and moves to a recessed position within the housing when the reservoir is filled with the medicament.
Claim 25
Dependent Claim
16 words
A medicament delivery device according to claim 1, wherein the container is integral with the housing.
Claim 26
Dependent Claim
23 words
A medicament delivery device according to claim 1, wherein the container is separate from the housing and is mounted thereon prior to use.
Claim 27
Dependent Claim
24 words
A medicament delivery device according to claim 1, wherein the penetrating means penetrates partially into but not entirely through the stopper prior to use.
Claim 28
Dependent Claim
35 words
A medicament delivery device according to claim 1, wherein the medicament is selected from peptides, proteins, hormones, analgesics, anti-migraine agents, anti-coagulant narcotic antagonists, chelating agents, anti-anginal agents, chemotherapy agents, sedatives, anti-neoplastics, protaglandins and antidiuretic agents.
Claim 29
Dependent Claim
33 words
A medicament delivery device according to claim 1, wherein the medicament is provided in the form of a semi-solid material which is reconstituted to a liquid form prior to use of the device.
Claim 30
Dependent Claim
55 words
A medicament delivery device comprising a housing having a skin-contacting surface, a reservoir within the housing, a hollow needle, in hinged relation to the housing, communicating with the reservoir extending, in use, through the periphery of the skin-contacting surface, and driving means for driving a medicament from the reservoir to a patient via the needle.
Claim 31
Dependent Claim
55 words
A medicament delivery device comprising a housing having a skin-contacting surface, a reservoir within the housing, a hollow needle, in hinged relation to the housing, communicating with the reservoir extending, in use, through the periphery of the skin-contacting surface, and driving means for driving a medicament from the reservoir to a patient via the needle.
Claim 32
Dependent Claim
17 words
A medicament delivery device according to claim 29, wherein the driving means comprises a gas generating apparatus.
Claim 33
Dependent Claim
21 words
A medicament delivery device according to claim 30, wherein the gas generating apparatus is in the form of an electrolytic cell.
Claim 34
Dependent Claim
23 words
A medicament delivery device according to claim 31, wherein the electrolytic cell comprises upper and lower plates and an electrolyte intermediate said plates.
Claim 35
Dependent Claim
16 words
A medicament delivery device according to claim 32, wherein the electrolytic cell further comprises a battery.
Claim 36
Dependent Claim
29 words
A medicament delivery device according to claim 31, wherein the electrolytic cell comprises a reservoir for a liquid electrolyte bounded in part by a gas permeable, liquid impermeable membrane.
Claim 37
Dependent Claim
16 words
A medicament delivery device according to claim 34, wherein the electrolytic cell further comprises a battery.
Claim 38
Dependent Claim
26 words
A medicament delivery device according to claim 30, wherein the gas generating apparatus comprises two substances which when brought into contact react to generate a gas.
Claim 39
Dependent Claim
17 words
A medicament delivery device according to claim 36, wherein the substances are an acid and a base.
Claim 40
Dependent Claim
76 words
A medicament delivery device according to claim 29, further comprising a filling mechanism for the reservoir integral with the housing, the filling mechanism being adapted to receive a container for the medicament, said container being sealed by a penetrable stopper, and the filling mechanism comprising means for penetrating the stopper, said penetrating means being in communication with the reservoir to allow the medicament to be transferred from the container to the reservoir via the filling mechanism.
Claim 41
Dependent Claim
32 words
A medicament delivery device according to claim 38, wherein the container is capable of sliding within the housing, and the stopper makes a leakproof sliding fit with the interior of the container.
Claim 42
Dependent Claim
65 words
A medicament delivery device according to claim 39, wherein the housing is provided with a bore which receives the container and the penetrating means is disposed on a stop within the bore, such that the stopper is penetrated and abuts against the stop when the container is pushed along the bore, the penetrated stopper acting as a piston to deliver the medicament from the container.
Claim 43
Dependent Claim
40 words
A medicament delivery device according to claim 40, wherein the penetrating means comprises a hollow needle and the stop is a rod extending within the bore, the needle communicating with the reservoir via a conduit extending internally of the rod.
Claim 44
Dependent Claim
36 words
A medicament delivery kit comprising: (a) A medicament delivery device according to claim 38; and (b) a container sealed by a penetrable stopper which stopper makes a leakproof sliding fit with the interior of the container.
Claim 45
Dependent Claim
35 words
A medicament delivery device according to claim 42, wherein the medicament is selected from peptides, proteins, hormones, analgesics, anti-migraine agents, anti-coagulant narcotic antagonists, chelating agents, anti-anginal agents, chemotherapy agents, sedatives, anti-neoplastics, protaglandins and antidiuretic agents.
Claim 46
Dependent Claim
15 words
A medicament delivery device according claim 38, wherein the container is integral with the housing.
Claim 47
Dependent Claim
22 words
A medicament delivery device according claim 38, wherein the container is separate from the housing and is mounted thereon prior to use.
Claim 48
Dependent Claim
35 words
A medicament delivery device according to claim 38, wherein the container protrudes from the housing prior to use and moves to a recessed position within the housing when the reservoir is filled with the medicament.
Claim 49
Dependent Claim
24 words
A medicament delivery device according to claim 38, wherein the penetrating means penetrates partially into but not entirely through the stopper prior to use.
Claim 50
Dependent Claim
21 words
A medicament delivery device according to claim 29, wherein the driving means is located intermediate the reservoir and the skin-contacting surface.
Claim 51
Dependent Claim
25 words
A medicament delivery device according to claim 48, wherein the driving means has a substantially flat configuration and is disposed parallel to the skin-contacting surface.
Claim 52
Dependent Claim
19 words
A medicament delivery device according to claim 49, wherein the driving means is located immediately above the skin-contacting surface.
Claim 53
Dependent Claim
16 words
A medicament delivery device according to claim 29, wherein the driving means comprises a swellable gel.
Claim 54
Dependent Claim
40 words
A medicament delivery device according to claim 51, wherein the swellable gel swells on contact with a liquid and the driving means further comprises a container containing such a liquid, and means for bringing the liquid and gel into contact.
Claim 55
Dependent Claim
32 words
A medicament delivery device according claim 29, wherein the medicament is provided in the form of a solid material which is reconstituted to a liquid form prior to use of the device.
Claim 56
Dependent Claim
17 words
A medicament delivery device according to claim 53, wherein the medicament is provided as a lyophilised solid.
Claim 57
Dependent Claim
60 words
A medicament delivery device according to claim 29, wherein the skin-contacting surface is in the form of a cover attached to the housing, said cover being movable between first and second positions, the needle being concealed by said cover when the cover is in said first position, and the needle being exposed when the cover is in said second position.
Claim 58
Dependent Claim
20 words
A medicament delivery device according to claim 55, wherein said cover is mounted on the housing by a hinge mechanism.
Claim 59
Dependent Claim
27 words
A medicament delivery device according to claim 56, wherein said cover is provided with a snap mechanism allowing it to snap between said first and second positions.
Claim 60
Dependent Claim
27 words
A medicament delivery device according to claim 55, wherein said cover is provided with a snap mechanism allowing it to snap between said first and second positions.
Claim 61
Dependent Claim
25 words
A medicament delivery device according claim 29, wherein a portion of the housing is transparent or translucent thereby allowing visual inspection of the reservoir contents.
Claim 62
Dependent Claim
35 words
A medicament delivery device according to claim 29, wherein the medicament is selected from peptides, proteins, hormones, analgesics, anti-migraine agents, anti-coagulant narcotic antagonists, chelating agents, anti-anginal agents, chemotherapy agents, sedatives, anti-neoplastics, protaglandins and antidiuretic agents.
Claim 63
Dependent Claim
33 words
A medicament delivery device according to claim 29, wherein the medicament is provided in the form of a semi-solid material which is reconstituted to a liquid form prior to use of the device.
Claim 64
Dependent Claim
118 words
A medicament delivery kit comprising: (a) a medicament delivery device comprising a housing, a reservoir within the housing, a filling mechanism for the reservoir integral with the housing and gas generated means for driving the medicament from the filled reservoir, the filling mechanism being adapted to receive a container for the medicament, said container being sealed by a penetrable stopper, and the filling mechanism comprising means for penetrating the stopper, said penetrating means being in communication with the reservoir to allow the medicament to be transferred from the container to the reservoir via the filling mechanism; and (b) a container sealed by a penetrable stopper which stopper makes a leakproof sliding fit with the interior of the container.
Claim 65
Dependent Claim
118 words
A medicament delivery kit comprising: (a) a medicament delivery device comprising a housing, a reservoir within the housing, a filling mechanism for the reservoir integral with the housing and gas generated means for driving the medicament from the filled reservoir, the filling mechanism being adapted to receive a container for the medicament, said container being sealed by a penetrable stopper, and the filling mechanism comprising means for penetrating the stopper, said penetrating means being in communication with the reservoir to allow the medicament to be transferred from the container to the reservoir via the filling mechanism; and (b) a container sealed by a penetrable stopper which stopper makes a leakproof sliding fit with the interior of the container.
Claim 66
Dependent Claim
35 words
A medicament delivery kit according to claim 62, wherein the medicament is selected from peptides, proteins, hormones, analgesics, anti-migraine agents, anti-coagulant narcotic antagonists, chelating agents, anti-anginal agents, chemotherapy agents, sedatives, anti-neoplastics, protaglandins and antidiuretic agents.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-09-28 | 2002-03-30 | 2002-09-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-09-28 | 2006-03-30 | 2006-09-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-09-28 | 2010-03-30 | 2010-09-29 | $7700.00 | Window Closed / Lapsed |