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US5811112A
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Oil-in-water cosmetic emulsions containing a stabilized protease
Assignee: Chesebrough Ponds USA Inc
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Filing: 1997-05-30
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Granted: 1998-09-22
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Expires: 2017-05-30
Abstract
Abstract Cosmetic oil-in-water emulsions which are intended to be left on the skin after application (not rinsed off) the emulsions incorporating a stabilized protease. The cosmetic emulsions useful in treatment of dry, flaky, rough, aged, wrinkled or cellulotic skin.
Inventors
- 👤 Prem Chandar
- 👤 Norman Kramer Richardson
- 👤 Alyse Battaglia
- 👤 Karla Jean Cicciari
- 👤 Kara Newell El-Kadi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 15:56
CPC Classifications
A; A61; A61Q; A61Q19/00; A61Q19/007; A61K; A61K8/00; A61K8/02; A61K8/04; A61K8/06; A61K8/062; A61K8/18; A61K8/30; A61K8/64; A61K8/66; A61Q19/08; A61K2800/00; A61K2800/40; A61K2800/52
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
109 words
An oil-in-water emulsion for a leave-on skin care composition the emulsion comprising: (a) from 1 wt % to 10 wt. % of droplets comprising a solid anhydrous protease distributed in a hydrophobic carrier, wherein the carrier has a melting point in the range of from 30° C. to about 80° C.; (b) at least 60% of water; (c) from 1 to 40 wt. % of an emollient which has a melting point in the range of from 30° C. to 80° C., wherein the emollient contains a hydrophobic hydrocarbon backbone and a hydrophilic polar headgroup, and wherein the emollient lowers the water activity of the emulsion to below 0.99.
Claim 2
Dependent Claim
109 words
An oil-in-water emulsion for a leave-on skin care composition the emulsion comprising: (a) from 1 wt % to 10 wt. % of droplets comprising a solid anhydrous protease distributed in a hydrophobic carrier, wherein the carrier has a melting point in the range of from 30° C. to about 80° C.; (b) at least 60% of water; (c) from 1 to 40 wt. % of an emollient which has a melting point in the range of from 30° C. to 80° C., wherein the emollient contains a hydrophobic hydrocarbon backbone and a hydrophilic polar headgroup, and wherein the emollient lowers the water activity of the emulsion to below 0.99.
Claim 3
Dependent Claim
22 words
The composition of claim 1, wherein the Caseinolytic Activity of the protease is at least 900 glycine unit per gram (GU/g) emulsion.
Claim 4
Dependent Claim
32 words
The composition of claim 1 wherein at least 10% of the Caseinolytic Activity of the protease is maintained on storage at an ambient temperature of 20°-25° C. for at least 6 months.
Claim 5
Dependent Claim
44 words
The composition of claim 1 wherein the protease: (1) has optimum activity between pH 5 and 9; (2) has specific activity greater than 8×10 5 GU/g of protease (3) has a broad substrate specificity as defined by an independence of specificity on primary structure.
Claim 6
Dependent Claim
15 words
The composition of claim 1 wherein the emulsion contains at least 80 wt. % water.
Claim 7
Dependent Claim
50 words
The composition of claim 1 wherein the emollient is selected from the group consisting of fatty acids, fatty alcohols, fatty acid esters of glycerol, fatty alcohol esters of glycerol, fatty alcohol esters of ethylene glycol, fatty alcohol esters of propylene glycol, fatty alcohol esters of lactyl lactate, and mixtures thereof.
Claim 8
Dependent Claim
13 words
The composition of claim 1, wherein the composition further contains a water-binding agent.
Claim 9
Dependent Claim
28 words
The composition of claim 6 wherein the water binding agent is selected from the group consisting of glycerol, a hydrophilic polymer, a clay, a gum, and mixtures thereof.
Claim 10
Dependent Claim
20 words
The composition of claim 1, wherein the size of the droplets ranges from about 100 μM to about 1,000 μM.
Claim 11
Dependent Claim
25 words
A cosmetic method of treating dry, flaky, cellulotic rough, aged, or wrinkled skin, the method comprising applying to the skin the composition of claim 1.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-09-21 | 2002-03-23 | 2002-09-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-09-21 | 2006-03-23 | 2006-09-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-09-21 | 2010-03-23 | 2010-09-22 | $7700.00 | Window Closed / Lapsed |