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US5807261A Expired / Lapsed US ⏱️ 0.0 years remaining

Noninvasive system for characterizing tissue in vivo

Assignee: JB IP Acquisition LLC
•
Filing: 1995-06-07
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Granted: 1998-09-15
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Expires: 2015-06-07
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Abstract

Abstract A tool for nondestructive interrogation of the tissue including a light source emitter and detector which may be mounted directly on the surgical tool in a tissue contacting surface for interrogation or mounted remotely and guided to the surgical field with fiber optic cables. The light source may be broadband and wavelength differentiation can be accomplished at the detector via filters or gratings, or using time, frequency, or space resolved methods. Alternatively, n discrete monochromatic light sources may be provided which are subsequently multiplexed into a single detector by time or by frequency multiplexing. The optical sensing elements can be built into a surgical tool end effector tip such as a tissue grasping tool which has cooperating jaws (bivalve or multi-element). In the preferred embodiment the light source (or the fiber optic guide) is mounted on one jaw and the detector (or fiber optic guide) is mounted in the opposing jaw so that the light emitter and detector are facing one another either directly (i.e., on the same optical axis when the tool is closed) or acutely (i.e., with intersecting optical axes so that the light emitted is detected). In this case, the sensor is working in a transmission modality. Arrangements with the optical components mounted on the same member of a single member or a multi member structure, operating in a reflective modality, are disclosed.

Inventors

  • 👤 David A. Benaron
  • 👤 Daniel S. Goldberger
  • 👤 David E. Goodman
  • 👤 Robert S. Smith

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 11:24
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/34; A61B17/3417; A61B17/3494; A61B18/00; A61B5/00; A61B5/0059; A61B5/0082; A61B5/0084; A61B5/0086; A61B5/68; A61B5/6846; A61B5/6847; A61B5/6848; G; G01; G01N; G01N21/00; G01N21/17; G01N21/47; G01N21/4795; A61B17/068; A61B17/28; A61B17/29; A61B17/3474; A61B18/04; A61B18/12; A61B18/14; A61B2017/00017; A61B2017/00022; A61B2017/00057; A61B2017/00061; A61B2017/00115; A61B2017/00119; A61B2017/00123; A61B17/00491; A61B2017/00504; A61B2017/00508; A61B2017/00535; A61B2017/00557; A61B90/00; A61B90/36; A61B90/361; A61B2090/3614; A61B2560/00; A61B2560/02; A61B2560/0266; A61B2560/0276; A61B2562/00; A61B2562/02; A61B2562/0233; A61B2562/0242; A61B2562/08; A61B5/0075

Claims Analysis

Total Claims: 28
Claim 1
Independent Claim 140 words
A system for characterizing tissue in vivo comprising: a source of electromagnetic radiation; a first window coupled to the source to launch the electromagnetic radiation into a tissue to be characterized; a second window to couple the electromagnetic radiation transmitted through said tissue; a spectrometer coupled to the second window, responsive to the coupled electromagnetic radiation, and having an output signal corresponding to a detection spectra of the tissue; a signal processor connected to the spectrometer output signal having a plurality of spectra records corresponding to a plurality of known tissue types, and operable to relate said detection spectra to said plurality of spectra records to identify the tissue illuminated as one of one of said plurality of known tissue types and none of said plurality of known tissue types, and generate an output signal characterizing the identified illuminated tissue.
Claim 2
Independent Claim 140 words
A system for characterizing tissue in vivo comprising: a source of electromagnetic radiation; a first window coupled to the source to launch the electromagnetic radiation into a tissue to be characterized; a second window to couple the electromagnetic radiation transmitted through said tissue; a spectrometer coupled to the second window, responsive to the coupled electromagnetic radiation, and having an output signal corresponding to a detection spectra of the tissue; a signal processor connected to the spectrometer output signal having a plurality of spectra records corresponding to a plurality of known tissue types, and operable to relate said detection spectra to said plurality of spectra records to identify the tissue illuminated as one of one of said plurality of known tissue types and none of said plurality of known tissue types, and generate an output signal characterizing the identified illuminated tissue.
Claim 3
Dependent Claim 29 words
The system of claim 1 wherein said plurality of spectra records includes a set of spectral records corresponding to distinct types of tissue classes, including ureter, liver, and kidney.
Claim 4
Dependent Claim 31 words
The system of claim 1 wherein said plurality of spectra records includes a set of spectral records corresponding to different pathological states of a selected tissue class including normal and cancerous.
Claim 5
Dependent Claim 62 words
The system of claim 1 wherein said plurality of spectra records includes a set of spectra records corresponding to a sequence of effects of a surgical intervention on a blood carrying tissue including normal blood flow, coagulated blood and over-coagulated blood in said tissue, wherein the blood carrying tissue contains at least one of an artery, a vein, and a capillary bed.
Claim 6
Dependent Claim 26 words
The system of claim 1 further comprising a display responsive to the signal processor output signal and having a display signal output characterizing the identified tissue.
Claim 7
Dependent Claim 37 words
The system of claim 5 wherein the display signal output is a data message selected from among the group consisting of a text message written on a video display, an audible message, and a visual non-text message.
Claim 8
Dependent Claim 38 words
The system of claim 1 further comprising: a surgical tool having a distal end; and a tip connected to the tool distal end, wherein the tip contains the first and second windows and has an end effector structure.
Claim 9
Dependent Claim 18 words
The system of claim 7 wherein said end effector structure further comprises means for performing a surgical intervention.
Claim 10
Dependent Claim 16 words
The system of claim 7 wherein the tip is detachably connected to the tool distal end.
Claim 11
Dependent Claim 49 words
The system of claim 7 wherein the tip further comprises an end effector structure selected from among the group consisting of a forceps, a knife, a scissors, a probe, a suction probe, an irrigation probe, an electrocautery tool, an electrosurgery tool, a hemostatic tool, a retractor and a clamp.
Claim 12
Dependent Claim 45 words
The system of claim 7 wherein the second window further comprises a first fiber optic guide in said tip, the system further comprising a second fiber optic guide optically connected to the first fiber optic guide to transmit the coupled electromagnetic radiation to the spectrometer.
Claim 13
Dependent Claim 35 words
The system of claim 7 wherein the spectrometer further comprises an optical demultiplexer separating the coupled electromagnetic radiation into at least two distinct wavelengths, said at least two distinct wavelengths corresponding to the detection spectra.
Claim 14
Dependent Claim 19 words
The system of claim 12 wherein the optical demultiplexer is one of a synchronous demultiplexer and a frequency demultiplexor.
Claim 15
Dependent Claim 16 words
The system of claim 7 wherein the source of electromagnetic radiation is a broadband light source.
Claim 16
Dependent Claim 19 words
The system of claim 7 wherein the source of electromagnetic radiation is a plurality of discrete light wavelength sources.
Claim 17
Dependent Claim 25 words
The system of claim 7 wherein the tip further comprises an identification code containing information corresponding to a plurality of operating characteristics of the tip.
Claim 18
Dependent Claim 77 words
The system of claim 7 wherein the signal processor further comprises an interlock output having a first signal in response to the identified tissue being one of a subset of the plurality of known tissue types, and wherein the tool further comprises a control system operating the tip to perform the surgical intervention, the control system having an input receiving the interlock output signal and being responsive to said interlock first signal to modify the surgical intervention.
Claim 19
Dependent Claim 26 words
The system of claim 17 wherein the tool further comprises a cutting instrument and is responsive to the interlock signal by not cutting the identified tissue.
Claim 20
Dependent Claim 48 words
The system of claim 7 wherein the tool further comprises an information code comprising data corresponding to a plurality of operating characteristics of the surgical tool, wherein the signal processor is responsive to said information code to adjust said signal processor operation according to said tool operating characteristics.
Claim 21
Dependent Claim 57 words
The system of claim 7 wherein the surgical tool further comprises an optical demultiplexor separating the detected electromagnetic radiation into at least two distinct wavelengths of the detected electromagnetic radiation, said at least two distinct wavelengths corresponding to the detection spectra, wherein the spectrometer further comprises an input signal corresponding to said at least two distinct wavelengths.
Claim 22
Dependent Claim 19 words
The system of claim 20 wherein the optical demultiplexor is one of a synchronous demultiplexor and a frequency demultiplexor.
Claim 23
Dependent Claim 59 words
The system of claim 7 wherein the tool contains the source of electromagnetic radiation, the tip further comprises a first fiber optic guide coupling the source in the tool to the first window in the tip, and the system further comprises a light source controller operatively connected to said tool to cause the source to emit the electromagnetic radiation.
Claim 24
Dependent Claim 49 words
The system of claim 22 wherein the tip further comprises a second fiber optic guide coupled to the second window in said tip, the system further comprising a third fiber optic guide optically connected to the first fiber optic guide to transmit the coupled electromagnetic radiation to the spectrometer.
Claim 25
Dependent Claim 52 words
The system of claim 22 wherein the surgical tool further comprises an optical demultiplexor separating the coupled electromagnetic radiation into at least two distinct wavelengths, said at least two distinct wavelengths corresponding to the detection spectra, wherein the spectrometer further comprises an input signal corresponding to said at least two distinct wavelengths.
Claim 26
Independent Claim 202 words
A system for characterizing tissue in vivo comprising: a source of electromagnetic radiation; a first window coupled to the source to launch the electromagnetic radiation into a tissue to be characterized; a second window to couple the electromagnetic radiation transmitted through said tissue; a spectrometer coupled to the second window, responsive to the coupled electromagnetic radiation, and having an output signal corresponding to a detection spectra of the tissue; a signal processor connected to the spectrometer output signal having a plurality of spectra records corresponding to a plurality of known tissue types, and operable to relate said detection spectra to said plurality of spectra records to identify the tissue illuminated as one of one of said plurality of known tissue types and none of said plurality of known tissue types, and generate an output signal characterizing the identified illuminated tissue; a surgical tool having a distal end; and a tip connected to the tool distal end, wherein the tip contains the first and second windows and has an end effector structure, wherein the tip contains the source of electromagnetic radiation; and a light source controller operatively connected to said source of electromagnetic radiation to cause the source to emit the electromagnetic radiation.
Claim 27
Independent Claim 202 words
A system for characterizing tissue in vivo comprising: a source of electromagnetic radiation; a first window coupled to the source to launch the electromagnetic radiation into a tissue to be characterized; a second window to couple the electromagnetic radiation transmitted through said tissue; a spectrometer coupled to the second window, responsive to the coupled electromagnetic radiation, and having an output signal corresponding to a detection spectra of the tissue; a signal processor connected to the spectrometer output signal having a plurality of spectra records corresponding to a plurality of known tissue types, and operable to relate said detection spectra to said plurality of spectra records to identify the tissue illuminated as one of one of said plurality of known tissue types and none of said plurality of known tissue types, and generate an output signal characterizing the identified illuminated tissue; a surgical tool having a distal end; and a tip connected to the tool distal end, wherein the tip contains the first and second windows and has an end effector structure, wherein the tip contains the source of electromagnetic radiation; and a light source controller operatively connected to said source of electromagnetic radiation to cause the source to emit the electromagnetic radiation.
Claim 28
Dependent Claim 16 words
The system of claim 25 wherein the source of electromagnetic radiation is a broadband light source.

References Cited (Backward Citations)

US2437916A Cited
US3674008A Cited
US3847483A Cited
US3961621A Cited
US3963019A Cited
US3941121A Cited
US4085756A Cited
US4421106A Cited
US4322164A Cited
US4295470A Cited
US4380240A Cited
US4269192A Cited
US4191191A Cited
US4273127A Cited
US4416285A Cited
US4299230A Cited
US4290433A Cited
US4311138A Cited
US4410020A Cited
US4356682A Cited
US4350148A Cited
US4509368A Cited
US4759348A Cited
US4448194A Cited
US4471781A Cited
US4658825A Cited
US4617940A Cited
US4532935A Cited
US4555179A Cited
US4527569A Cited
US4633885A Cited
US4502487A Cited
US4601710A Cited
US4601710B1 Cited
US5002051A Cited
US5140984A Cited
US4854320A Cited
US4539586B1 Cited
US4539586A Cited
US5140989A Cited
US5139025A Cited
US4622974A Cited
US4667229A Cited
US4773097A Cited
US4948974A Cited
US5088493A Cited
US4566438A Cited
US4682585A Cited
US5199431A Cited
US4763662A Cited
US4650327A Cited
US4930516B1 Cited
US4930516A Cited
US5000752A Cited
US4864648A Cited
US4765736A Cited
US4887606A Cited
US4902280A Cited
US5030206A Cited
US4784150A Cited
US4810875A Cited
US4872187A Cited
US4805623A Cited
US4917097A Cited
US5053016A Cited
US4910404A Cited
US4951677A Cited
US4959063A Cited
US4905668A Cited
US5137355A Cited
US4981138A Cited
US5066288A Cited
US5112330A Cited
US5057695A Cited
US5119815A Cited
US4972827A Cited
US4911148A Cited
US4945895A Cited
US5002557A Cited
US5099123A Cited
US4975581A Cited
DE3920706A1 Cited
US4970757A Cited
US4998527A Cited
US5104383A Cited
US5078712A Cited
US5131398A Cited
US5070874A Cited
US5219345A Cited
US5037433A Cited
US5152278A Cited
US5114407A Cited
US5154709A Cited
US5100402A Cited
US5116353B1 Cited
US5116353A Cited
US5030207A Cited
US5271380A Cited
US5213105A Cited
US5104382A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2001-09-14 2002-03-16 2002-09-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2005-09-14 2006-03-16 2006-09-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2009-09-14 2010-03-16 2010-09-15 $7700.00 Window Closed / Lapsed

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