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US5773563A Expired / Lapsed US ⏱️ 0.0 years remaining

Absorbable ε-caprolactone polymers

Assignee: Poly Med Inc
•
Filing: 1996-06-03
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Granted: 1998-06-30
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Expires: 2016-06-03
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Abstract

Abstract Crystane, low melting ε-Caprolactone polymers which undergo accelerated hydrolysis, and their use as lubricant coatings and/or as coatings containing bioactive agents, as carriers of viable cells, and as coatings for open-cell microporous template or constucts for tissue regeneration; the polymers bearing basic functionalities can be linked ionically or covalently to the ester chain which induces autocatalyzed hydrolysis.

Inventors

  • 👤 Shalaby W. Shalaby

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 14:18
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/28; A61L27/34; A61L17/00; A61L17/06; A61L17/10; A61L17/12; A61L17/14; A61L17/145; A61L24/00; A61L24/04; A61L24/046; A61L27/14; A61L27/18; A61L27/50; A61L29/00; A61L29/08; A61L29/085; C; C08; C08G; C08G63/00; C08G63/91; C08G63/912

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 25 words
Crystalline nitrogenous polyesters comprising predominantly ε-caprolactone polymer sequences linked ionically or covalently to amine-bearing structures which represent 1 to 20 percent of the total weight.
Claim 2
Dependent Claim 25 words
Crystalline nitrogenous polyesters comprising predominantly ε-caprolactone polymer sequences linked ionically or covalently to amine-bearing structures which represent 1 to 20 percent of the total weight.
Claim 3
Dependent Claim 23 words
The nitrogenous polyester polymers of claim 1, wherin the amine-bearing structures represent 2 to 10 percent of the total weight of the system.
Claim 4
Dependent Claim 26 words
The nitrogenous polyester polymers of claim 1, wherein the amount of ε-caprolactone-based components of the polymer represent 90 to 99 percent of the polyester chain sequences.
Claim 5
Dependent Claim 26 words
The nitrogenous polyester polymers of claim 1, wherein the amount of ε-caprolactone-based components of the polymer represent 95 to 99 percent of the polyester chain sequences.
Claim 6
Dependent Claim 20 words
The nitrogenous polyester polymers of claim 1, wherein a minor component of the polyester chain is made of glycolate sequences.
Claim 7
Dependent Claim 17 words
The nitrogenous polyester polymers of claim 1, wherein the polyester chain is terminated with a carboxyl group.
Claim 8
Dependent Claim 28 words
The nitrogenous polyester polymers of claim 1, wherein the polyester chain is terminated with a carboxyl group and wherein the polyester is ionically linked to an amine-bearing molecule.
Claim 9
Dependent Claim 29 words
The nitrogenous polyester polymers of claim 1, wherein the polyester chain is terminated with a carboxyl group and the polyester is ionically linked to lysine or its potassium salt.
Claim 10
Dependent Claim 18 words
The nitrogenous polyester polymers of claim 1, wherein the amine-bearing structures are covalently bonded to the chain end.
Claim 11
Dependent Claim 27 words
The nitrogenous polyester polymers of claim 1, wherein the amine-bearing structures are covalently bonded to the chain end and the amine-bearing structure is based on 1-methyl-4-aminomethyl piperidine.
Claim 12
Dependent Claim 20 words
The nitrogenous polyester polymers of claim 1, wherein the amine-bearing structures are internally placed in the polyester through covalent bonding.
Claim 13
Dependent Claim 15 words
The nitrogenous polyester polymers of claim 1, wherein the amine-bearing structure is based on 3,3'-diamino-N-methyl-dipropylamine.
Claim 14
Dependent Claim 22 words
The nitrogenous polyester polymers of claim 1 having an inherent viscosity on hexafluoroisopropyl alcohol at (0.1 g/dl concentration) of 0.05 to 0.35.
Claim 15
Dependent Claim 23 words
The nitrogenous polyester polymers of claim 1 having an inherent viscosity on hexafluoroisopropyl alcohol at (0.1 g/dl concentration) of 0.1 to 0.20 dl/g.

References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2001-06-29 2001-12-29 2002-06-30 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2005-06-29 2005-12-29 2006-06-30 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2009-06-29 2009-12-29 2010-06-30 $7700.00 Window Closed / Lapsed

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