Patent US5700901A successfully refreshed from Google Patents.
US5700901A
Expired / Lapsed
US
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Resorbable mouldings and process for producing them
Assignee: Boehringer Ingelheim GmbH
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Filing: 1995-01-11
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Granted: 1997-12-23
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Expires: 2015-01-11
Abstract
Abstract The invention relates to resorbable mouldings and processes for producing them.
Inventors
- 👤 Achim Hurst
- 👤 Wladis Winkler-Gwienek
- 👤 Berthold Buchholz
- 👤 Dieter Bendix
- 👤 Gunther Entenmann
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 16:13
CPC Classifications
A; A61; A61L; A61L31/00; A61L31/14; A61L31/148; A61L31/04; A61L31/041; A61L31/06
Claims Analysis
Total Claims: 27
Claim 1
Independent Claim
64 words
A process for producing resorbable moldings which comprises feeding a polylactide to an injection molding means operating under pressure and at a cylinder temperature of at least 175° C. to produce a resorbable molding having an inherent viscosity between 0.8 and 4.5 dl/g., an initial tensile strength of at least 45N/mm 2 , and an initial bending strength of at least 90N/mm 2 .
Claim 2
Dependent Claim
64 words
A process for producing resorbable moldings which comprises feeding a polylactide to an injection molding means operating under pressure and at a cylinder temperature of at least 175° C. to produce a resorbable molding having an inherent viscosity between 0.8 and 4.5 dl/g., an initial tensile strength of at least 45N/mm 2 , and an initial bending strength of at least 90N/mm 2 .
Claim 3
Dependent Claim
10 words
A resorbable molding produced by the process of claim 1.
Claim 4
Dependent Claim
37 words
The process of claim 1 in which the polylactide comprises poly(L-lactide), poly(D-lactide) or copolymers derived therefrom with other comonomers in the form of copolymerizable cyclic esters, the proportion of comonomer being not more than 30% by weight.
Claim 5
Dependent Claim
10 words
A resorbable molding produced by the process of claim 3.
Claim 6
Dependent Claim
30 words
The process of claim 3 in which the comonomer is selected from the group consisting of D,L-lactide, meso-lactide, glycolide, dioxanone, trimethylene carbonate, and lactones of β-hydroxybutyric acid and β-hydroxyvaleric acid.
Claim 7
Dependent Claim
10 words
A resorbable molding produced by the process of claim 5.
Claim 8
Dependent Claim
42 words
A process for producing resorbable moldings which comprises feeding a mixture of a polylactide or copolymers derived therefrom and solid particles of a high molecular weight resorbable polyester additive to an injection molding means operating under pressure to produce a resorbable molding.
Claim 9
Dependent Claim
42 words
A process for producing resorbable moldings which comprises feeding a mixture of a polylactide or copolymers derived therefrom and solid particles of a high molecular weight resorbable polyester additive to an injection molding means operating under pressure to produce a resorbable molding.
Claim 10
Dependent Claim
28 words
The process claim 7 wherein the high molecular weight resorbable polyester additive is present in an effective amount to increase the tensile strength and percentage elongation after fracture.
Claim 11
Dependent Claim
22 words
The process of claim 8 wherein the additive is present in an amount of from 1 to 30% by weight of additive.
Claim 12
Dependent Claim
22 words
The process of claim 8 wherein the additive is present in an amount of from 1 to 15% by weight of additive.
Claim 13
Dependent Claim
10 words
A resorbable molding produced by the process of claim 7.
Claim 14
Dependent Claim
29 words
The process of claim 7 wherein the high molecular weight additive is selected from the group consisting of poly(D,L-lactide), poly(D-lactide), poly(meso-lactide), polyglycolide, polytrimethylene carbonate, polydioxanone, poly-ε-caprolactone and mixtures thereof.
Claim 15
Dependent Claim
38 words
The process of claim 7 wherein the additive is a copolymer selected from the group consisting of poly(L-lactide-co-D,L-lactide), poly(L-lactide-co-meso-lactide), poly(L-lactide-co-glycolide), poly(L-lactide-co-trimethylene carbonate), poly(L-lactide-co-ε-caprolactone), poly(D,L-lactide-co-meso-lactide), poly(D,L-lactide-co-glycolide), poly(D,L-lactide-co-trimethylene carbonate), poly(D,L-lactide-co-ε-caprolactone), poly(meso-lactide-co-glycolide), poly(meso-lactide-co-trimethylene carbonate), poly(meso-lactide-co-ε-caprolactone), poly(glycolide-co-trimethylene carbonate), poly(glycolide-co-ε-caprolactone) and mixtures thereof.
Claim 16
Dependent Claim
34 words
A process for producing resorbable moldings which comprises feeding a mixture of a polylactide and acetyltributyl-citrate, glycerol triacetate or mixtures thereof to an injection molding means operating under pressure to produce a resorbable molding.
Claim 17
Dependent Claim
34 words
A process for producing resorbable moldings which comprises feeding a mixture of a polylactide and acetyltributyl-citrate, glycerol triacetate or mixtures thereof to an injection molding means operating under pressure to produce a resorbable molding.
Claim 18
Dependent Claim
10 words
A resorbable molding produced by the process of claim 14.
Claim 19
Dependent Claim
62 words
A resorbable moulding based on poly(lactide), or copolymers derived thereof, characterised in that it contains a high molecular additive consisting of a resorbable polyester in an effective amount in order to increase the tensile strength and percentage elongation after fracture, whereas poly (p-dioxaonone) is disclaimed as additive and the content of glycolide of the total composition is less than 65% by weight.
Claim 20
Dependent Claim
39 words
A moulding according to claim 16, characterised in that it consists of poly(L-lactide, poly(D-lactide) or copolymers derived therefrom with other comonomers in the form of copolymerisable cyclic esters the proportion of comonomer being not more than 30% by weight.
Claim 21
Dependent Claim
26 words
A moulding according to claim 17, characterised in that the comonomer is D,L-lactide, meso-lactide, glycolide, dioxanone, trimethylenecarbonate or a lactone of β-hydroxybutyric acid and/or β-hydroxyvaleric acid.
Claim 22
Dependent Claim
18 words
A resorbable moulding according to claims 16, 17 or 18 characterised in that it contains poly(L-lactide) or poly(L-lactide-co-D,L-lactide).
Claim 23
Dependent Claim
25 words
A resorbable moulding according to claim 19, characterised in that the high molecular additive is poly(D,L-lactide), poly(D-lactide), poly(meso-lactide), polyglycolide, polytrimethylene carbonate, polycaprolactone or mixtures thereof.
Claim 24
Dependent Claim
39 words
A resorbable moulding according to claims 16, 17 or 18 characterised in that the additive is a copolymer selected from the group consisting of poly(L-lactide-co-D,L-lactide) poly(L-lactide-co-meso-lactide) poly(L-lactide-co-glycolide) poly(L-lactide-c-trimethylene carbonate) poly(L-lactide-co-ε,-caprolactone) poly(D,L-lactide-co-meso-lactide) poly(D,L-lactide-co-glycolide) poly(D,L-lactide-co-trimethylene carbonate) poly(D,L-lactide-co-ε-caprolactone) poly(meso-lactide-co-glycolide poly(meso-lactide-co-trimethylene carbonate) poly(meso-lactide-co-ε-caprolactone).
Claim 25
Dependent Claim
20 words
A resorbable moulding according to claim 16, characterised in that it contains 1 to 85% by weight of the additive.
Claim 26
Dependent Claim
33 words
A moulding according to claim 16, characterised in that it has a elongation after fracture of at least 2% in the initial state and under physiological conditions for a period of 8 weeks.
Claim 27
Dependent Claim
18 words
The moulding according to claim 17, wherein the proportion of comonomer is not more than 15% by weight.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-12-22 | 2001-06-23 | 2001-12-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-12-22 | 2005-06-23 | 2005-12-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-12-22 | 2009-06-23 | 2009-12-23 | $7700.00 | Window Closed / Lapsed |