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US5690691A
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Gastro-intestinal pacemaker having phased multi-point stimulation
Assignee: VIRGINIA PATENT FOUNDATION UNIVERSITY OF
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Filing: 1996-05-08
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Granted: 1997-11-25
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Expires: 2016-05-08
Abstract
Abstract A portable or implantable gastric pacemaker includes multiple electrodes that are positionable on the inner or outer surface of an organ in the gastro-intestinal tract and which are individually programmed to deliver a phased electrical stimulation to pace peristaltic movement of material through the GI tract. The pacemaker will accommodate variations in pulse amplitudes, pulse durations, pulse periods, and relative pulse phasing among the electrodes. Computer control can be used to adjust and vary all stimulation parameters delivered by the electrodes to achieve effective treatment and re-training of an organ for natural pacing. The pacemaker can be programmed with parameters to enhance or accelerate peristaltic movement through the gastric tract or to attenuate the peristaltic movement to treat such conditions eating disorders or diarrhea.
Inventors
- 👤 Jian Dez Chen
- 👤 Richard W. McCallum
- 👤 Ronald Williams
- 👤 Robert Ross
- 👤 Zhiyue Lin
- 👤 Jonathan Tillack
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 10:05
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/36; A61N1/36007
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
104 words
A method for electrically stimulating at least one organ in the gastro-intestinal tract for peristaltic movement, comprising the steps of: connecting a plurality of electrodes to at least one organ in the gastro-intestinal tract of a patient along a peristaltic flow path, each of said plurality of electrodes being connected at a different location along said peristaltic flow path; and providing electrical pulses to said organ from each one of said plurality of electrodes, said electrical pulsed provided by said plurality of electrodes being in a phased relationship according to a desired peristaltic flow through said at least one organ in said gastrointestinal tract.
Claim 2
Independent Claim
104 words
A method for electrically stimulating at least one organ in the gastro-intestinal tract for peristaltic movement, comprising the steps of: connecting a plurality of electrodes to at least one organ in the gastro-intestinal tract of a patient along a peristaltic flow path, each of said plurality of electrodes being connected at a different location along said peristaltic flow path; and providing electrical pulses to said organ from each one of said plurality of electrodes, said electrical pulsed provided by said plurality of electrodes being in a phased relationship according to a desired peristaltic flow through said at least one organ in said gastrointestinal tract.
Claim 3
Dependent Claim
34 words
The method of claim 1 further comprising the step of independently regulating a pulse amplitude, a pulse timing, and a pulse duration for said electrical pulses for each one of said plurality of electrodes.
Claim 4
Dependent Claim
58 words
A method for electrically stimulating an organ as recited in claim 2 wherein said organ is a stomach and further comprising the step of selecting a pulse amplitude in the range of 0.1 to 10 mA and a pulse duration in the range of 10 to 1000 ms for at least one electrode of said plurality of electrodes.
Claim 5
Dependent Claim
51 words
A method for electrically stimulating an organ as recited in claim 1 wherein said organ is a stomach and further comprising the step of selecting a pulse frequency of 1.5 to 4 cycles per minute for each electrode in said plurality of electrodes with a selected phase offset between adjacent electrodes.
Claim 6
Dependent Claim
52 words
A method for electrically stimulating an organ as recited in claim 1 wherein said organ is a small intestine and further comprising the step of selecting a pulse frequency of 9 to 12.5 cycles per minute for each electrode in said plurality of electrodes with a selected phase offset between adjacent electrodes.
Claim 7
Dependent Claim
74 words
The method of claim 1 further comprising the steps of: locating said plurality of electrodes on said organ with at least a first electrode being relatively closer to a distal end of said gastrointestinal tract than a second electrode and said second electrode being relatively more forward in said gastrointestinal tract than said first electrode; and developing a phased pulse regimentation of said organ which progresses from said first electrode to said second electrode.
Claim 8
Dependent Claim
23 words
The method of claim 6 wherein said second electrode provides a relatively higher amplitude pulse stimulation to said organ than said first electrode.
Claim 9
Dependent Claim
74 words
The method of claim 1 further comprising the steps of: locating said plurality of electrodes on said organ with at least a first electrode being relatively closer to a distal end of said gastrointestinal tract than a second electrode and said second electrode being relatively more forward in said gastrointestinal tract than said first electrode; and developing a phased pulse regimentation of said organ which progresses from said second electrode to said first electrode.
Claim 10
Dependent Claim
23 words
The method of claim 8 wherein said second electrode provides a relatively higher amplitude pulse stimulation to said organ than said first electrode.
Claim 11
Dependent Claim
74 words
A gastric pacemaker for controlling the peristaltic pace of digestive organs, comprising: a plurality of stimulation electrodes sequentially positionable on at least one digestive organ along a peristaltic flow path; controller for controlling electrical pulse parameters for each of said plurality of stimulation electrodes in a phased relationship according to a desired peristaltic flow; and circuitry for providing electrical pulses to each of said plurality of stimulation electrodes in accordance with said phased relationship.
Claim 12
Dependent Claim
74 words
A gastric pacemaker for controlling the peristaltic pace of digestive organs, comprising: a plurality of stimulation electrodes sequentially positionable on at least one digestive organ along a peristaltic flow path; controller for controlling electrical pulse parameters for each of said plurality of stimulation electrodes in a phased relationship according to a desired peristaltic flow; and circuitry for providing electrical pulses to each of said plurality of stimulation electrodes in accordance with said phased relationship.
Claim 13
Dependent Claim
30 words
A gastric pacemaker as recited in claim 10 further comprising a sensor electrode connectable to said digestive organ for sensing a response of said organ to an electrical pulse stimulation.
Claim 14
Dependent Claim
35 words
A gastric pacemaker as recited in claim 10 wherein at least one of said plurality of stimulation electrodes also functions as a sensing electrode for sensing a response of said organ to an electrical pulse.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-11-24 | 2001-05-26 | 2001-11-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-11-24 | 2005-05-26 | 2005-11-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-11-24 | 2009-05-26 | 2009-11-25 | $7700.00 | Window Closed / Lapsed |